Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
pmid:
Fadden K et al. Steroid metabolism along the gastrointestinal tract of the cannulated pig. 1999 Eur. J. Cancer Prev. pmid:10091041
Araya Z and Wikvall K 6alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. 1999 Biochim. Biophys. Acta pmid:10216279
Narain PK et al. Cholesterol enhances membrane-damaging properties of model bile by increasing the intervesicular-intermixed micellar concentration of hydrophobic bile salts. 1999 J. Surg. Res. pmid:10334899
Funaoka M et al. Tauroursodeoxycholic acid enhances phagocytosis of the cultured rat Kupffer cell. 1999 J. Gastroenterol. Hepatol. pmid:10440209
Alvarez C and Bass BL Role of transforming growth factor-beta in growth and injury response of the pancreatic duct epithelium in vitro. 1999 Mar-Apr J. Gastrointest. Surg. pmid:10457343
Paolini M et al. Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes. 1999 Hepatology pmid:10462380
Frijters CM et al. The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids. 1999 J. Lipid Res. pmid:10552998
Martinez-Diez MC et al. Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture. 2000 Biochim. Biophys. Acta pmid:10657584
Pignol D et al. Critical role of micelles in pancreatic lipase activation revealed by small angle neutron scattering. 2000 J. Biol. Chem. pmid:10660587
Pérez Méndez S et al. Enantiomeric resolution of selenoamino acid derivatives by micellar electrokinetic chromatography (MEKC) with sodium dodecyl sulphate and a mixture of beta-cyclodextrin and taurodeoxycholic acid as chiral selectors. 2000 Biomed. Chromatogr. pmid:10664549
Foley DP et al. Bile acids in xenogeneic ex-vivo liver perfusion: function of xenoperfused livers and compatibility with human bile salts and porcine livers. 2000 Transplantation pmid:10670634
Paolini M et al. Mechanism for the prevention of cholestasis involving cytochrome P4503A overexpression. 2000 J. Investig. Med. pmid:10695269
Hertl M et al. Hydrophilic bile salts protect bile duct epithelium during cold preservation: a scanning electron microscopy study. 2000 Liver Transpl. pmid:10719022
Hrbasová M et al. Artificial lipid-protein complexes accelerate cholesterol crystallisation in model bile. 2000 Int. J. Biochem. Cell Biol. pmid:10785358
Leclerc MC et al. Identification, characterization, and immunolocalization of a nucleoside triphosphate diphosphohydrolase in pig liver. 2000 Arch. Biochem. Biophys. pmid:10845716
Spinosa MR et al. On the fate of ingested Bacillus spores. 2000 Res. Microbiol. pmid:10919516
Song C et al. Selective activation of liver X receptor alpha by 6alpha-hydroxy bile acids and analogs. 2000 Steroids pmid:10936612
Ohlsson B et al. Acute taurodeoxycholate-induced pancreatitis in the rat is associated with hyperCCKemia. 2000 Int. J. Pancreatol. pmid:10952401
Dominguez C et al. Interactions of bile salt micelles and colipase studied through intermolecular nOes. 2000 FEBS Lett. pmid:11018532
Grill JP et al. Bile salt toxicity to some bifidobacteria strains: role of conjugated bile salt hydrolase and pH. 2000 Can. J. Microbiol. pmid:11068673
Dastgheib S et al. Analyses of glycosphingolipids using clam, Mercenaria mercenaria, ceramide glycanase. 2000 Meth. Enzymol. pmid:11070873
de las Heras G et al. [Selective intestinal bacterial decontamination in experimental acute pancreatitis]. 2000 Gastroenterol Hepatol pmid:11149219
Venkatasubramanian J et al. Differences in Ca(2+) signaling underlie age-specific effects of secretagogues on colonic Cl(-) transport. 2001 Am. J. Physiol., Cell Physiol. pmid:11171585
Kahn ME et al. Possible mechanisms of diarrheal side effects associated with the use of a novel chemotherapeutic agent, flavopiridol. 2001 Clin. Cancer Res. pmid:11234889
Sunami Y et al. Gallbladder dysfunction enhances physical density but not biochemical metastability of biliary vesicles. 2000 Dig. Dis. Sci. pmid:11258563
Crandall WV and Lowe ME Colipase residues Glu64 and Arg65 are essential for normal lipase-mediated fat digestion in the presence of bile salt micelles. 2001 J. Biol. Chem. pmid:11278590
Radwan MA and Aboul-Enein HY The effect of absorption enhancers on the initial degradation kinetics of insulin by alpha-chymotrypsin. 2001 Int J Pharm pmid:11292547
Strauch ED et al. Bile salt stimulates intestinal epithelial cell migration through TGFbeta after wounding. 2001 J. Surg. Res. pmid:11319879
Hino A et al. Effects of deoxycholic acid and its epimers on lipid peroxidation in isolated rat hepatocytes. 2001 J. Biochem. pmid:11328589
pmid:11330410
Takikawa Y et al. The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes. 2001 Gastroenterology pmid:11375961
Moschetta A et al. Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo. 2001 J. Hepatol. pmid:11394647
Tiss A et al. Effects of gum arabic on lipase interfacial binding and activity. 2001 Anal. Biochem. pmid:11412003
Baumgartner U et al. Colchicine inhibits taurodeoxycholate transport in pericentral but not in periportal hepatocytes. 2001 Biochim. Biophys. Acta pmid:11420119
Lanzarotto F et al. Effect of chronic administration of tauro-hyodeoxycholic acid on biliary bile acid composition and on biliary lipid secretion in humans. 2001 Scand. J. Gastroenterol. pmid:11521991
Creveld LD et al. DSC studies of Fusarium solani pisi cutinase: consequences for stability in the presence of surfactants. 2001 Biophys. Chem. pmid:11527580
Baumgartner U et al. Pericentral hepatocytes translocate hydrophilic bile acids more rapidly than hydrophobic ones. 2001 Dig. Dis. Sci. pmid:11680582
van Erpecum KJ et al. Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles. 2001 J. Hepatol. pmid:11682027
Torchia EC et al. Differential modulation of cellular death and survival pathways by conjugated bile acids. 2001 BMC Biochem. pmid:11707155
Bani D et al. The vasorelaxant hormone relaxin induces changes in liver sinusoid microcirculation: a morphologic study in the rat. 2001 J. Endocrinol. pmid:11739020
Scheibner J et al. Indirect evidence that intestinal bile salt absorption in rats and hamsters is under positive feedback control. 2001 Z Gastroenterol pmid:11778152
Rao YP et al. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. 2002 Hepatology pmid:11826403
Dib M et al. Role of mast cells in the development of pancreatitis-induced multiple organ dysfunction. 2002 Br J Surg pmid:11856129
Lin JM et al. Comparison of three different anionic surfactants for the separation of hydrophobic compounds by nonaqueous capillary electrophoresis. 2002 Electrophoresis pmid:11870742
Carubbi F et al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. 2002 Biochim. Biophys. Acta pmid:11923098
Voronina S et al. Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology. 2002 J. Physiol. (Lond.) pmid:11927668
Graf D et al. Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. 2002 Gastroenterology pmid:11984527
pmid:11991004
pmid:12007103
Pandak WM et al. Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes. 2002 Hepatology pmid:12029625
Aubert E et al. Site-directed mutagenesis of the basic N-terminal cluster of pancreatic bile salt-dependent lipase. Functional significance. 2002 J. Biol. Chem. pmid:12110666
pmid:12115803
Venneman NG et al. Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles. 2002 Biochim. Biophys. Acta pmid:12117566
Yapoudjian S et al. Surface fluorescence resonance energy transfer studies on interfacial adsorption of Thermomyces (humicola) lanuginosa lipase, using monomolecular films of cis-parinaric acid. 2002 Biopolymers pmid:12209462
Piepoli AL et al. Tauroursodeoxycholic acid reduces damaging effects of taurodeoxycholic acid on fundus gastric mucosa. 2002 Arch. Physiol. Biochem. pmid:12221520
Hartmann G et al. Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia. 2002 J. Pharmacol. Exp. Ther. pmid:12235261
pmid:12240947
Okolo C et al. Effects of bile acids on dog pancreatic duct epithelial cell secretion and monolayer resistance. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12381517
Artusi M et al. Buccal delivery of thiocolchicoside: in vitro and in vivo permeation studies. 2003 Int J Pharm pmid:12480286
Lamireau T et al. Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. 2003 Life Sci. pmid:12527037
Baiocchi L et al. Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats. 2003 J. Hepatol. pmid:12547401
Um JY et al. In vitro cellular interaction and absorption of dispersed cubic particles. 2003 Int J Pharm pmid:12593938
Haraldsen P et al. Multimodal management - of value in fulminant acute pancreatitis? 2003 Pancreatology pmid:12649560
Sánchez Pozzi EJ et al. Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis. 2003 J. Pharmacol. Exp. Ther. pmid:12663690
Strauch ED et al. NF-kappaB regulates intestinal epithelial cell and bile salt-induced migration after injury. 2003 Ann. Surg. pmid:12677145
Baumgartner U et al. Repetitive short-term bile duct obstruction and relief causes reproducible and reversible bile acid regurgitation. 2003 J. Surg. Res. pmid:12697405
Song IS et al. Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers. 2003 Pharm. Res. pmid:12739767
Moschetta A et al. Basolateral Ca2+-dependent K+-channels play a key role in Cl- secretion induced by taurodeoxycholate from colon mucosa. 2003 Mar-Apr Biol. Cell pmid:12799067
Smídková M et al. Effect of drugs on cholesterol crystallization in an artificial bile model and relation of this effect to drug binding to albumin. 2003 Fundam Clin Pharmacol pmid:12803572
Chen W and Gluud C Bile acids for primary sclerosing cholangitis. 2003 Cochrane Database Syst Rev pmid:12804480
Zheng ZY and Bernstein C Bile salt/acid induction of DNA damage in bacterial cells: effect of taurine conjugation. 1992 Nutr Cancer pmid:1437652
Figge A et al. Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis. 2004 J. Biol. Chem. pmid:14570929
Strauch ED et al. Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa B-induced expression of transforming growth factor-beta. 2003 J. Am. Coll. Surg. pmid:14644286
pmid:14704997
Komichi D et al. Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes. 2003 Dig. Dis. Sci. pmid:14714619
Mühlbauer M et al. Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14726307
Yamaguchi J et al. Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression. 2004 Surgery pmid:14739857
Kubitz R et al. Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase. 2004 Gastroenterology pmid:14762791
Chen CC et al. Effects of nitric oxide synthase inhibitors on retrograde bile salt-induced pancreatitis rats. 2004 J Chin Med Assoc pmid:15077884
Voronina SG et al. Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim. 2004 J. Biol. Chem. pmid:15084611
Campbell NB et al. Physiological concentrations of bile salts inhibit recovery of ischemic-injured porcine ileum. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15087278
Camarota LM et al. Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3. 2004 J. Biol. Chem. pmid:15105424
Aeed PA et al. Effect of membrane perturbants on the activity and phase distribution of inositol phosphorylceramide synthase; development of a novel assay. 2004 Biochemistry pmid:15222759
Worku ML et al. Chemotactic response of Helicobacter pylori to human plasma and bile. 2004 J. Med. Microbiol. pmid:15272070
Rani K et al. Measurement of bile acid in serum and bile with arylamine-glass-bound 3alpha-hydroxysteroid dehydrogenase and diaphorase. 2004 Anal. Biochem. pmid:15301946
Fang Y et al. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes. 2004 Hepatology pmid:15382121
Matyash V et al. Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. 2004 PLoS Biol. pmid:15383841
Murata Y et al. Adsorption of bile acid by chitosan-orotic acid salt and its application as an oral preparation. 2004 Chem. Pharm. Bull. pmid:15467231
Stevens RD et al. Proton magnetic resonance studies of the aggregation of taurine-conjugated bile salts. 1992 J. Lipid Res. pmid:1552230
Toledo A et al. Taurodeoxycholate stimulates intestinal cell proliferation and protects against apoptotic cell death through activation of NF-kappaB. 2004 Dig. Dis. Sci. pmid:15573924
Jurek D et al. Bile acid induced gene expression in LT97 colonic adenoma cells. 2005 Food Chem. Toxicol. pmid:15582199
Lim HJ et al. Isolation of cholesterol-lowering lactic acid bacteria from human intestine for probiotic use. 2004 J. Vet. Sci. pmid:15613825
Trotta M et al. Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique. 2005 Int J Pharm pmid:15620868
pmid:15810635
pmid:15823032
Leveau P et al. Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant. 2005 Biochem. Pharmacol. pmid:15826603
Khurana S et al. Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. 2005 Eur. J. Pharmacol. pmid:15964566
Song KH et al. Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts. 2005 J Control Release pmid:15979756
Pomponio R et al. Microemulsion electrokinetic chromatography of corticosteroids. Effect of surfactants and cyclodextrins on the separation selectivity. 2005 J Chromatogr A pmid:16013593