Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
pmid:
Fadden K et al. Steroid metabolism along the gastrointestinal tract of the cannulated pig. 1999 Eur. J. Cancer Prev. pmid:10091041
Araya Z and Wikvall K 6alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. 1999 Biochim. Biophys. Acta pmid:10216279
Narain PK et al. Cholesterol enhances membrane-damaging properties of model bile by increasing the intervesicular-intermixed micellar concentration of hydrophobic bile salts. 1999 J. Surg. Res. pmid:10334899
Funaoka M et al. Tauroursodeoxycholic acid enhances phagocytosis of the cultured rat Kupffer cell. 1999 J. Gastroenterol. Hepatol. pmid:10440209
Alvarez C and Bass BL Role of transforming growth factor-beta in growth and injury response of the pancreatic duct epithelium in vitro. 1999 Mar-Apr J. Gastrointest. Surg. pmid:10457343
Paolini M et al. Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes. 1999 Hepatology pmid:10462380
Frijters CM et al. The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids. 1999 J. Lipid Res. pmid:10552998
Martinez-Diez MC et al. Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture. 2000 Biochim. Biophys. Acta pmid:10657584
Pignol D et al. Critical role of micelles in pancreatic lipase activation revealed by small angle neutron scattering. 2000 J. Biol. Chem. pmid:10660587
Pérez Méndez S et al. Enantiomeric resolution of selenoamino acid derivatives by micellar electrokinetic chromatography (MEKC) with sodium dodecyl sulphate and a mixture of beta-cyclodextrin and taurodeoxycholic acid as chiral selectors. 2000 Biomed. Chromatogr. pmid:10664549
Foley DP et al. Bile acids in xenogeneic ex-vivo liver perfusion: function of xenoperfused livers and compatibility with human bile salts and porcine livers. 2000 Transplantation pmid:10670634
Paolini M et al. Mechanism for the prevention of cholestasis involving cytochrome P4503A overexpression. 2000 J. Investig. Med. pmid:10695269
Hertl M et al. Hydrophilic bile salts protect bile duct epithelium during cold preservation: a scanning electron microscopy study. 2000 Liver Transpl. pmid:10719022
Hrbasová M et al. Artificial lipid-protein complexes accelerate cholesterol crystallisation in model bile. 2000 Int. J. Biochem. Cell Biol. pmid:10785358
Leclerc MC et al. Identification, characterization, and immunolocalization of a nucleoside triphosphate diphosphohydrolase in pig liver. 2000 Arch. Biochem. Biophys. pmid:10845716
Spinosa MR et al. On the fate of ingested Bacillus spores. 2000 Res. Microbiol. pmid:10919516
Song C et al. Selective activation of liver X receptor alpha by 6alpha-hydroxy bile acids and analogs. 2000 Steroids pmid:10936612
Ohlsson B et al. Acute taurodeoxycholate-induced pancreatitis in the rat is associated with hyperCCKemia. 2000 Int. J. Pancreatol. pmid:10952401
Dominguez C et al. Interactions of bile salt micelles and colipase studied through intermolecular nOes. 2000 FEBS Lett. pmid:11018532