Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
Baumgartner U et al. Colchicine inhibits taurodeoxycholate transport in pericentral but not in periportal hepatocytes. 2001 Biochim. Biophys. Acta pmid:11420119
Martinez-Diez MC et al. Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture. 2000 Biochim. Biophys. Acta pmid:10657584
Roy AB The sulphatase of ox liver. XXII. Further observations on the cerebroside sulphatase activity of sulphatase A. 1979 Biochim. Biophys. Acta pmid:36164
Oelberg DG et al. Bile salt-induced calcium fluxes in artificial phospholipid vesicles. 1988 Biochim. Biophys. Acta pmid:2827771
Aromataris EC et al. Store-operated Ca(2+) channels and Stromal Interaction Molecule 1 (STIM1) are targets for the actions of bile acids on liver cells. 2008 Biochim. Biophys. Acta pmid:18342630
Araya Z and Wikvall K 6alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. 1999 Biochim. Biophys. Acta pmid:10216279
Canioni P et al. Circular dichroism study of horse colipase interaction with bile salt. 1981 Biochim. Biophys. Acta pmid:7295779
Erlanson-Albertsson C Measurement of the binding of colipase to a triacylglycerol substrate. 1980 Biochim. Biophys. Acta pmid:7370284
Carubbi F et al. Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. 2002 Biochim. Biophys. Acta pmid:11923098
Alvaro D et al. Influence of tauroursodeoxycholic and taurodeoxycholic acids on hepatic metabolism and biliary secretion of phosphatidylcholine in the isolated rat liver. 1986 Biochim. Biophys. Acta pmid:3756193