Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

Cross Reference

Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

Download all related citations
Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
Campbell NB et al. Physiological concentrations of bile salts inhibit recovery of ischemic-injured porcine ileum. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15087278
Mühlbauer M et al. Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14726307
Cao W et al. Expression of bile acid receptor TGR5 in gastric adenocarcinoma. 2013 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:23238937
Zhou Y et al. Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs. 2010 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20203063
Cai SY et al. The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. 2007 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:17567710
Venkatasubramanian J et al. Differences in Ca(2+) signaling underlie age-specific effects of secretagogues on colonic Cl(-) transport. 2001 Am. J. Physiol., Cell Physiol. pmid:11171585
Kanchanapoo J et al. Role of protein kinase C-delta in the age-dependent secretagogue action of bile acids in mammalian colon. 2007 Am. J. Physiol., Cell Physiol. pmid:17898130
Lang J et al. Synergistic effect of hydrochloric acid and bile acids on the pars esophageal mucosa of the porcine stomach. 1998 Am. J. Vet. Res. pmid:9736398
Reiner JL et al. Determination of perfluorinated compounds in human plasma and serum Standard Reference Materials using independent analytical methods. 2011 Anal Bioanal Chem pmid:21912833
Ruhaak LR et al. Glycan labeling strategies and their use in identification and quantification. 2010 Anal Bioanal Chem pmid:20225063
Tiss A et al. Effects of gum arabic on lipase interfacial binding and activity. 2001 Anal. Biochem. pmid:11412003
Schägger H and von Jagow G Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form. 1991 Anal. Biochem. pmid:1812789
Rani K et al. Measurement of bile acid in serum and bile with arylamine-glass-bound 3alpha-hydroxysteroid dehydrogenase and diaphorase. 2004 Anal. Biochem. pmid:15301946
Shaw R et al. Bile acids LIII. Application of reverse-phase high-pressure liquid chromatography to the analysis of conjugated bile acids in bile samples. 1978 Anal. Biochem. pmid:655409
Liang G et al. Highly sensitive chiral analysis of amino acids by in-line single drop microextraction and capillary electrophoresis with laser-induced fluorescence detection. 2010 Anal. Chim. Acta pmid:20850587
Fimognari C et al. Apoptosis and modulation of cell cycle control by bile acids in human leukemia T cells. 2009 Ann. N. Y. Acad. Sci. pmid:19723064
Strauch ED et al. NF-kappaB regulates intestinal epithelial cell and bile salt-induced migration after injury. 2003 Ann. Surg. pmid:12677145
Turner DJ et al. Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression. 2007 Ann. Surg. pmid:17435549
Mrówczynska L et al. Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts. 2005 Sep-Oct Anticancer Res. pmid:16101123
Chen S et al. Study on improvement of extracellular production of recombinant Thermobifida fusca cutinase by Escherichia coli. 2011 Appl. Biochem. Biotechnol. pmid:21594592
Brown AJ and Kolattukudy PE Evidence that pancreatic lipase is responsible for the hydrolysis of cutin, a biopolyester present in mammalian diet, and the role of bile salt and colipase in this hydrolysis. 1978 Arch. Biochem. Biophys. pmid:708069
Holmes EH and Macher BA Specificity of fucose transfer to GlcNAc residues of extended chain neolacto-series glycolipids catalyzed by human alpha 1-->3fucosyltransferases: effect of the lipidic environment on the myeloid enzyme form. 1993 Arch. Biochem. Biophys. pmid:8442661
Leclerc MC et al. Identification, characterization, and immunolocalization of a nucleoside triphosphate diphosphohydrolase in pig liver. 2000 Arch. Biochem. Biophys. pmid:10845716
Shim WS et al. Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract. 2008 Arch. Pharm. Res. pmid:18481027
Chae HW et al. Effect of ion-pair formation with bile salts on the in vitro cellular transport of berberine. 2008 Arch. Pharm. Res. pmid:18277615
Piepoli AL et al. Tauroursodeoxycholic acid reduces damaging effects of taurodeoxycholic acid on fundus gastric mucosa. 2002 Arch. Physiol. Biochem. pmid:12221520
Bernstein C et al. Carcinogenicity of deoxycholate, a secondary bile acid. 2011 Arch. Toxicol. pmid:21267546
De Bernardi di Valserra M et al. Chronic toxicity of taurohyodeoxycholic acid in rats. 1993 Arzneimittelforschung pmid:8216447
Feletti F et al. Chronic toxicity of taurohyodeoxycholic acid in dogs. 1993 Arzneimittelforschung pmid:8216448
Feletti F et al. Reproductive toxicity of taurohyodeoxycholic acid. 1993 Arzneimittelforschung pmid:8216449
Tripodi AS et al. In vitro and in vivo mutagenicity studies on taurohyodeoxycholic acid. 1993 Arzneimittelforschung pmid:8216450
Li YT et al. Occurrence of ceramide-glycanase in the earthworm, Lumbricus terrestris. 1987 Biochem. Biophys. Res. Commun. pmid:3689409
Noshiro M et al. The involvement of cytochrome b5 in 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol 25-hydroxylation and taurodeoxycholate 7 alpha-hydroxylation of rat liver. 1982 Biochem. Biophys. Res. Commun. pmid:7115387
Raufman JP et al. Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cells. 2011 Biochem. Biophys. Res. Commun. pmid:22027145
Murakami K et al. Partial purification and characterization of taurodeoxycholate 7 alpha-monooxygenase. 1980 Biochem. Biophys. Res. Commun. pmid:7396953
Verkade HJ et al. Interactions between organic anions, micelles and vesicles in model bile systems. 1996 Biochem. J. pmid:9003381
McIntyre JC et al. The role of aromatic side chain residues in micelle binding by pancreatic colipase. Fluorescence studies of the porcine and equine proteins. 1987 Biochem. J. pmid:3663193
Yedgar S and Gatt S Enzymic hydrolysis of sphingomyelin in the presence of bile salts. 1980 Biochem. J. pmid:6248032
Castro J et al. A small component of the endoplasmic reticulum is required for store-operated Ca2+ channel activation in liver cells: evidence from studies using TRPV1 and taurodeoxycholic acid. 2009 Biochem. J. pmid:19007332
Gatt S et al. Effect of bile salts on the hydrolysis of gangliosides, glycoproteins and neuraminyl-lactose by the neuraminidase of Clostridium perfringens. 1981 Biochem. J. pmid:6272704
Piessen G et al. Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. 2007 Biochem. J. pmid:17037983
Campbell CH et al. Incorporation of mannose 6-phosphate receptors into liposomes. Receptor topography and binding of alpha-mannosidase. 1983 Biochem. J. pmid:6311183
Fluharty AL et al. Bile salt activation of cerebroside sulphate sulphohydrolase. 1980 Biochem. J. pmid:6109529
Cheng K et al. Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line. 2007 Biochem. Pharmacol. pmid:17222808
Leveau P et al. Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant. 2005 Biochem. Pharmacol. pmid:15826603
Narayanan VS and Storch J Fatty acid transfer in taurodeoxycholate mixed micelles. 1996 Biochemistry pmid:8652524
Aeed PA et al. Effect of membrane perturbants on the activity and phase distribution of inositol phosphorylceramide synthase; development of a novel assay. 2004 Biochemistry pmid:15222759
Donovan JM and Jackson AA Transbilayer movement of fully ionized taurine-conjugated bile salts depends upon bile salt concentration, hydrophobicity, and membrane cholesterol content. 1997 Biochemistry pmid:9298964
Wieloch T et al. High-resolution proton magnetic resonance study of porcine colipase and its interactions with taurodeoxycholate. 1979 Biochemistry pmid:570855
Albalak A et al. Effects of submicellar bile salt concentrations on biological membrane permeability to low molecular weight non-ionic solutes. 1996 Biochemistry pmid:8672496