Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
Funaoka M et al. Tauroursodeoxycholic acid enhances phagocytosis of the cultured rat Kupffer cell. 1999 J. Gastroenterol. Hepatol. pmid:10440209
Bani D et al. The vasorelaxant hormone relaxin induces changes in liver sinusoid microcirculation: a morphologic study in the rat. 2001 J. Endocrinol. pmid:11739020
Girardet JM et al. Study of mechanism of lipolysis inhibition by bovine milk proteose-peptone component 3. 1993 J. Dairy Sci. pmid:8408864
Meira SM et al. Probiotic potential of Lactobacillus spp. isolated from Brazilian regional ovine cheese. 2012 J. Dairy Res. pmid:23171587
Stange EF et al. Role of primary and secondary bile acids as feedback inhibitors of bile acid synthesis in the rat in vivo. 1989 J. Clin. Invest. pmid:2738150
Reichen J Role of the hepatic artery in canalicular bile formation by the perfused rat liver. A multiple indicator dilution study. 1988 J. Clin. Invest. pmid:3284914
Devor DC et al. Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84) 1993 J. Clin. Invest. pmid:7693758
Dharmsathaphorn K et al. Cl- secretion induced by bile salts. A study of the mechanism of action based on a cultured colonic epithelial cell line. 1989 J. Clin. Invest. pmid:2547841
Gaskin KJ et al. Colipase and maximally activated pancreatic lipase in normal subjects and patients with steatorrhea. 1982 J. Clin. Invest. pmid:7056854
Field M Bile salt-induced diarrhea: the cellular mechanism. 1993 J. Clin. Invest. pmid:8227323
Johnson LF and Harmon JW Experimental esophagitis in a rabbit model. Clinical relevance. 1986 J. Clin. Gastroenterol. pmid:3090135
Aumatell A and Wells RJ Determination of a cardiac antiarrhythmic, tricyclic antipsychotics and antidepressants in human and animal urine by micellar electrokinetic capillary chromatography using a bile salt. 1995 J. Chromatogr. B, Biomed. Appl. pmid:7581909
Burkard I et al. Differentiated quantification of human bile acids in serum by high-performance liquid chromatography-tandem mass spectrometry. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:16182619
Naoi M et al. Microassay for GM1 ganglioside beta-galactosidase activity using high-performance liquid chromatography. 1988 J. Chromatogr. pmid:3133384
Carsberg CJ et al. Ultraviolet radiation-induced melanogenesis in human melanocytes. Effects of modulating protein kinase C. 1994 J. Cell. Sci. pmid:7531203
Raufman JP et al. Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling. 2008 J. Cell. Physiol. pmid:18064605
Keating N et al. Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells. 2009 J. Cell. Mol. Med. pmid:19583809
Martoni C et al. Investigation of microencapsulated BSH active lactobacillus in the simulated human GI tract. 2007 J. Biomed. Biotechnol. pmid:18273409
Crandall WV and Lowe ME Colipase residues Glu64 and Arg65 are essential for normal lipase-mediated fat digestion in the presence of bile salt micelles. 2001 J. Biol. Chem. pmid:11278590
Aubert E et al. Site-directed mutagenesis of the basic N-terminal cluster of pancreatic bile salt-dependent lipase. Functional significance. 2002 J. Biol. Chem. pmid:12110666
Pignol D et al. Critical role of micelles in pancreatic lipase activation revealed by small angle neutron scattering. 2000 J. Biol. Chem. pmid:10660587
Kispal G et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. 1986 J. Biol. Chem. pmid:3771531
Murakami K and Okuda K Purification and characterization of taurodeoxycholate 7 alpha-monooxygenase in rat liver. 1981 J. Biol. Chem. pmid:7263676
Freie AB et al. Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles. 2006 J. Biol. Chem. pmid:16431912
Momsen WE et al. Interfacial structure and lipase action. Characterization of taurodeoxycholate-didecanoylglycerol monolayers by physical and kinetic methods. 1979 J. Biol. Chem. pmid:479165
Patton JS et al. Binding of porcine pancreatic lipase and colipase in the absence of substrate studies by two-phase partition and affinity chromatography. 1978 J. Biol. Chem. pmid:659413
Campbell CH and Rome LH Coated vesicles from rat liver and calf brain contain lysosomal enzymes bound to mannose 6-phosphate receptors. 1983 J. Biol. Chem. pmid:6138357
Shefer S et al. Metabolism of iso-bile acids in the rat. 1982 J. Biol. Chem. pmid:7035450
Schmidt DR et al. Regulation of bile acid synthesis by fat-soluble vitamins A and D. 2010 J. Biol. Chem. pmid:20233723
Voronina SG et al. Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells: comparison of different modes of evaluating DeltaPsim. 2004 J. Biol. Chem. pmid:15084611
Camarota LM et al. Carboxyl ester lipase cofractionates with scavenger receptor BI in hepatocyte lipid rafts and enhances selective uptake and hydrolysis of cholesteryl esters from HDL3. 2004 J. Biol. Chem. pmid:15105424
Bourbon-Freie A et al. Trp-107 and trp-253 account for the increased steady state fluorescence that accompanies the conformational change in human pancreatic triglyceride lipase induced by tetrahydrolipstatin and bile salt. 2009 J. Biol. Chem. pmid:19346257
Li SC et al. A protein activator for the enzymic hydrolysis of GM2 ganglioside. 1981 J. Biol. Chem. pmid:7240201
Kobayashi T and Suzuki K A taurodeoxycholate-activated galactosylceramidase in the murine intestine. 1981 J. Biol. Chem. pmid:7451495
Figge A et al. Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis. 2004 J. Biol. Chem. pmid:14570929
Hino A et al. Effects of deoxycholic acid and its epimers on lipid peroxidation in isolated rat hepatocytes. 2001 J. Biochem. pmid:11328589
Kupper J et al. The flagellar bundle of Halobacterium salinarium is inserted into a distinct polar cap structure. 1994 J. Bacteriol. pmid:8051038
Strauch ED et al. Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa B-induced expression of transforming growth factor-beta. 2003 J. Am. Coll. Surg. pmid:14644286
Helgason T et al. Impact of surfactant properties on oxidative stability of beta-carotene encapsulated within solid lipid nanoparticles. 2009 J. Agric. Food Chem. pmid:19691283
Xu Y et al. Freeze-dried grape powder attenuates mitochondria- and oxidative stress-mediated apoptosis in liver cells. 2009 J. Agric. Food Chem. pmid:19754144
Orioni B et al. Polymorphic behavior in protein-surfactant mixtures: the water-bovine serum albumin-sodium taurodeoxycholate system. 2006 J Phys Chem B pmid:16800527
Hanus M and Zhorov E Bile acid salt binding with colesevelam HCl is not affected by suspension in common beverages. 2006 J Pharm Sci pmid:16937334
Roda A et al. Effect of basic cholane derivatives on intestinal cholic acid metabolism: in vitro and in vivo activity. 1992 J Pharm Sci pmid:1640360
Selvam S et al. A photophysical study on the role of bile salt hydrophobicity in solubilizing amphotericin B aggregates. 2009 J Pharm Sci pmid:19283765
Dai J et al. Impact of bile acids on the growth of human cholangiocarcinoma via FXR. 2011 J Hematol Oncol pmid:21988803
Khafagy el-S et al. Effect of cell-penetrating peptides on the nasal absorption of insulin. 2009 J Control Release pmid:18930084
Aguirre TAS et al. Coated minispheres of salmon calcitonin target rat intestinal regions to achieve systemic bioavailability: Comparison between intestinal instillation and oral gavage. 2016 J Control Release pmid:27480451
Song KH et al. Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts. 2005 J Control Release pmid:15979756
Borné J et al. Vesicle formation and other structures in aqueous dispersions of monoolein and sodium oleate. 2003 J Colloid Interface Sci pmid:16256485
Asaro F et al. 23Na and 35/37Cl as NMR probes of growth and shape of sodium taurodeoxycholate micellar aggregates in the presence of NaCl. 2013 J Colloid Interface Sci pmid:23127873