Taurodeoxycholic acid

Taurodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Taurodeoxycholic acid is associated with abnormalities such as Ischemia and Wiskott-Aldrich Syndrome. The involved functions are known as Cell Proliferation, Transcriptional Activation, Phosphorylation, Anabolism and Biochemical Pathway. Taurodeoxycholic acid often locates in Body tissue, Epithelium, Blood, Mucous Membrane and Hepatic. The associated genes with Taurodeoxycholic acid are NOX5 gene, GPBAR1 gene, NR1H4 gene and SLC33A1 gene. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid.

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Introduction

To understand associated biological information of Taurodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Taurodeoxycholic acid?

Taurodeoxycholic acid is suspected in Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Taurodeoxycholic acid

MeSH term MeSH ID Detail
Colitis, Ulcerative D003093 24 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Cholestasis D002779 23 associated lipids
Birth Weight D001724 23 associated lipids
Shock, Hemorrhagic D012771 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Tay-Sachs Disease D013661 2 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Taurodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Taurodeoxycholic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Taurodeoxycholic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Taurodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Taurodeoxycholic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Taurodeoxycholic acid

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Per page 10 20 50 100 | Total 449
Authors Title Published Journal PubMed Link
Shekels LL et al. Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids. 1996 J. Lab. Clin. Med. pmid:8592097
Narayanan VS and Storch J Fatty acid transfer in taurodeoxycholate mixed micelles. 1996 Biochemistry pmid:8652524
Muraca M et al. Protective effect of tauroursodeoxycholate against acute gastric mucosal injury induced by hydrophobic bile salts. 1996 Dig. Dis. Sci. pmid:8654150
Albalak A et al. Effects of submicellar bile salt concentrations on biological membrane permeability to low molecular weight non-ionic solutes. 1996 Biochemistry pmid:8672496
Smit JW et al. Does the HMG-CoA reductase inhibitor pravastatin influence nucleation of cholesterol crystals in supersaturated model bile? 1996 Eur J Gastroenterol Hepatol pmid:8724016
Oude Elferink RP et al. Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein. 1996 J. Lipid Res. pmid:8725158
Heuman DM et al. Adsorption of mixtures of bile salt taurine conjugates to lecithin-cholesterol membranes: implications for bile salt toxicity and cytoprotection. 1996 J. Lipid Res. pmid:8728319
Trawick JD et al. Rat hepatoma L35 cells, a liver-differentiated cell line, display resistance to bile acid repression of cholesterol 7 alpha-hydroxylase. 1996 J. Lipid Res. pmid:8728321
DeLong LJ and Nichols JW Time-resolved fluorescence anisotropy of fluorescent-labeled lysophospholipid and taurodeoxycholate aggregates. 1996 Biophys. J. pmid:8785303
Van Erpecum KJ et al. Effects of bile salt hydrophobicity on crystallization of cholesterol in model bile. 1996 Eur. J. Clin. Invest. pmid:8864423