MeSH term | MeSH ID | Detail |
---|---|---|
Insulin Resistance | D007333 | 99 associated lipids |
Hypertension | D006973 | 115 associated lipids |
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Insulin Resistance | D007333 | 99 associated lipids |
Hypertension | D006973 | 115 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ejiri S et al. | Cellular distribution of thrombomodulin as an early marker for warm ischemic liver injury in porcine liver transplantation: protective effect of prostaglandin I2 analogue and tauroursodeoxycholic acid. | 2001 | Transplantation | pmid:11330532 |
Calmus Y and Podevin P | Tauroursodeoxycholic acid for the cytoprotection of liver grafts during cold storage: a new aspect of its anti-apoptotic properties? | 2001 | Transplantation | pmid:11408962 |
Falasca L et al. | Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: a pilot study in transplant recipients. | 2001 | Transplantation | pmid:11397961 |
Ramalho RM et al. | Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. | 2008 | Trends Mol Med | pmid:18218342 |
Roma MG et al. | Dynamic localization of hepatocellular transporters in health and disease. | 2008 | World J. Gastroenterol. | pmid:19058304 |
Roda A et al. | A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon. | 2007 | World J. Gastroenterol. | pmid:17373743 |
Gnewuch C et al. | Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease. | 2009 | World J. Gastroenterol. | pmid:19575493 |
Beuers U | Effects of bile acids on hepatocellular signaling and secretion. | 1997 Jul-Aug | Yale J Biol Med | pmid:9626754 |
Park JY et al. | Bile acid analysis in biliary tract cancer. | 2006 | Yonsei Med. J. | pmid:17191311 |
Shi Z et al. | [Tauroursodeoxycholic acid suppresses endoplasmic reticulum stress in pulmonary tissues of intermittent hypoxia mice]. | 2015 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:26643417 |
Cui H et al. | [Experimental study of the permeability of Fel Ursi's in eye]. | 2006 | Zhonghua Yan Ke Za Zhi | pmid:17386143 |