Tauroursodeoxycholic acid

Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.

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Introduction

To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tauroursodeoxycholic acid?

Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid

MeSH term MeSH ID Detail
Hypertension D006973 115 associated lipids
Insulin Resistance D007333 99 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Tauroursodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tauroursodeoxycholic acid?

Related references are published most in these journals:

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What functions are associated with Tauroursodeoxycholic acid?


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What lipids are associated with Tauroursodeoxycholic acid?

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What genes are associated with Tauroursodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tauroursodeoxycholic acid?

Disease model

Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with Tauroursodeoxycholic acid

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Authors Title Published Journal PubMed Link
Crocenzi FA et al. Galactosamine prevents ethinylestradiol-induced cholestasis. 2006 Drug Metab. Dispos. pmid:16554370
Plösch T et al. Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16614371
Petruzzelli M et al. Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury. 2006 Dig. Dis. Sci. pmid:16615001
van Minnen LP et al. Cholesterol crystals enhance and phospholipids protect against pancreatitis induced by hydrophobic bile salts: a rat model study. 2006 Pancreas pmid:16670619
Solá S et al. Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid beta-peptide-induced apoptosis. 2006 Mol. Endocrinol. pmid:16728529
Kosters A et al. The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice. 2006 J. Lipid Res. pmid:16741293
Vaidya SS and Gerk PM Lack of interaction between tauroursodeoxycholate and ATP-binding cassette transporter isoform G2 (ABCG2). 2006 May-Jun Mol. Pharm. pmid:16749862
Zhang W et al. Binding studies of bile acids using the native fluorescence of the tryptophan residue Of Bax protein. 2006 Biosci. Rep. pmid:16850250
Kim HS et al. [Modulation of colon cancer cell invasiveness induced by deoxycholic acid]. 2006 Korean J Gastroenterol pmid:16861876
pmid:16872555