Cui H et al. |
[Experimental study of the permeability of Fel Ursi's in eye]. |
2006 |
Zhonghua Yan Ke Za Zhi |
pmid:17386143
|
Shi Z et al. |
[Tauroursodeoxycholic acid suppresses endoplasmic reticulum stress in pulmonary tissues of intermittent hypoxia mice]. |
2015 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:26643417
|
Park JY et al. |
Bile acid analysis in biliary tract cancer. |
2006 |
Yonsei Med. J. |
pmid:17191311
|
Beuers U |
Effects of bile acids on hepatocellular signaling and secretion. |
1997 Jul-Aug |
Yale J Biol Med |
pmid:9626754
|
Roma MG et al. |
Dynamic localization of hepatocellular transporters in health and disease. |
2008 |
World J. Gastroenterol. |
pmid:19058304
|
Roda A et al. |
A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon. |
2007 |
World J. Gastroenterol. |
pmid:17373743
|
Gnewuch C et al. |
Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease. |
2009 |
World J. Gastroenterol. |
pmid:19575493
|
Ramalho RM et al. |
Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. |
2008 |
Trends Mol Med |
pmid:18218342
|
Ejiri S et al. |
Cellular distribution of thrombomodulin as an early marker for warm ischemic liver injury in porcine liver transplantation: protective effect of prostaglandin I2 analogue and tauroursodeoxycholic acid. |
2001 |
Transplantation |
pmid:11330532
|
Ishigami F et al. |
Bile salt tauroursodeoxycholic acid modulation of Bax translocation to mitochondria protects the liver from warm ischemia-reperfusion injury in the rat. |
2001 |
Transplantation |
pmid:11740392
|
Calmus Y and Podevin P |
Tauroursodeoxycholic acid for the cytoprotection of liver grafts during cold storage: a new aspect of its anti-apoptotic properties? |
2001 |
Transplantation |
pmid:11408962
|
Falasca L et al. |
Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: a pilot study in transplant recipients. |
2001 |
Transplantation |
pmid:11397961
|
Falasca L et al. |
Tauroursodeoxycholate reduces ischemic damage in human allografts: a biochemical and ultrastructural study. |
2000 |
Transplant. Proc. |
pmid:10700964
|
Baiocchi L et al. |
TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway. |
2008 |
Transpl. Int. |
pmid:18435680
|
Hertl M et al. |
Tauroursodeoxycholate ameliorates reperfusion injury after pig liver transplantation. |
1999 |
Transpl. Int. |
pmid:10654358
|
Crocenzi FA et al. |
Role of bile salts in colchicine-induced hepatotoxicity. Implications for hepatocellular integrity and function. |
1997 |
Toxicology |
pmid:9230445
|
Wong MK et al. |
Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells. |
2016 |
Toxicol. Sci. |
pmid:26803847
|
Zhang Y et al. |
Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury. |
2012 |
Toxicol. Sci. |
pmid:22461449
|
Rolo AP et al. |
Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis. |
2004 |
Toxicol. Sci. |
pmid:14976352
|
Cho JG et al. |
Tauroursodeoxycholic acid, a bile acid, promotes blood vessel repair by recruiting vasculogenic progenitor cells. |
2015 |
Stem Cells |
pmid:25407160
|
Hakim F et al. |
Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice. |
2015 |
Sleep |
pmid:25325461
|
Hohenester S et al. |
Primary biliary cirrhosis. |
2009 |
Semin Immunopathol |
pmid:19603170
|
Ozcan U et al. |
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. |
2006 |
Science |
pmid:16931765
|
Kawasaki N et al. |
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue. |
2012 |
Sci Rep |
pmid:23150771
|
Muramatsu-Kato K et al. |
Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress. |
2015 |
Sci Rep |
pmid:26581663
|
Ishimura S et al. |
Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury. |
2014 |
Sci Rep |
pmid:25373918
|
Kim JS et al. |
Tauroursodeoxycholic acid enhances the pre-implantation embryo development by reducing apoptosis in pigs. |
2012 |
Reprod. Domest. Anim. |
pmid:22151574
|
Rodrigues CM et al. |
Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12721362
|
Purkayastha S et al. |
Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:21282643
|
Keene CD et al. |
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12149470
|
Dubrey S et al. |
The transthyretin amyloidoses: advances in therapy. |
2015 |
Postgrad Med J |
pmid:26048914
|
Trottier J et al. |
Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. |
2011 |
PLoS ONE |
pmid:21760958
|
Ma Y et al. |
Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. |
2012 |
PLoS ONE |
pmid:22493744
|
Yang JS et al. |
Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice. |
2010 |
PLoS ONE |
pmid:21079772
|
Úriz M et al. |
Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat. |
2011 |
PLoS ONE |
pmid:22194894
|
Sheu ML et al. |
Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth. |
2007 |
PLoS ONE |
pmid:17971859
|
Nguyen MT et al. |
Regulation of chemokine and chemokine receptor expression by PPARγ in adipocytes and macrophages. |
2012 |
PLoS ONE |
pmid:22529965
|
Mantopoulos D et al. |
Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. |
2011 |
PLoS ONE |
pmid:21961034
|
Fernández-Sánchez L et al. |
Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats. |
2017 |
PLoS ONE |
pmid:28542454
|
Zhang JY et al. |
Inhibition of endoplasmic reticulum stress improves mouse embryo development. |
2012 |
PLoS ONE |
pmid:22808162
|
Rani S et al. |
Tauroursodeoxycholic acid (TUDCA) attenuates pressure overload-induced cardiac remodeling by reducing endoplasmic reticulum stress. |
2017 |
PLoS ONE |
pmid:28426781
|
Groenendyk J et al. |
Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis. |
2016 |
PLoS ONE |
pmid:27441395
|
Fang L et al. |
Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. |
2013 |
PLoS ONE |
pmid:23593240
|
Turdi S et al. |
Tauroursodeoxycholic acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular Ca2+ anomalies. |
2013 |
PLoS ONE |
pmid:23667647
|
Gómez-Vicente V et al. |
Neuroprotective Effect of Tauroursodeoxycholic Acid on N-Methyl-D-Aspartate-Induced Retinal Ganglion Cell Degeneration. |
2015 |
PLoS ONE |
pmid:26379056
|
Koyama S et al. |
Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells. |
2015 |
PLoS ONE |
pmid:26288223
|
Yao XH et al. |
Prenatal ethanol exposure causes glucose intolerance with increased hepatic gluconeogenesis and histone deacetylases in adult rat offspring: reversal by tauroursodeoxycholic acid. |
2013 |
PLoS ONE |
pmid:23544086
|
Yu KN et al. |
Titanium Dioxide Nanoparticles Induce Endoplasmic Reticulum Stress-Mediated Autophagic Cell Death via Mitochondria-Associated Endoplasmic Reticulum Membrane Disruption in Normal Lung Cells. |
2015 |
PLoS ONE |
pmid:26121477
|
Cheng S et al. |
Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stress. |
2015 |
PLoS ONE |
pmid:25915041
|
Gupta S et al. |
Prevention of acute kidney injury by tauroursodeoxycholic acid in rat and cell culture models. |
2012 |
PLoS ONE |
pmid:23152827
|
Mališová L et al. |
Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes. |
2013 |
PLoS ONE |
pmid:24312631
|
Fang L et al. |
Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells. |
2013 |
PLoS ONE |
pmid:23977286
|
Ropelle ER et al. |
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition. |
2010 |
PLoS Biol. |
pmid:20808781
|
Yang X et al. |
Activation of autophagy by unfolded proteins during endoplasmic reticulum stress. |
2016 |
Plant J. |
pmid:26616142
|
Tanaka Y et al. |
The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice. |
2015 |
Pharmacol. Res. |
pmid:26005208
|
Xiang X et al. |
Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans. |
2009 |
Pharmacogenet. Genomics |
pmid:19387419
|
Megaraj V et al. |
Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2). |
2011 |
Pharmacogenet. Genomics |
pmid:21691255
|
Daood MJ et al. |
Lipid peroxidation is not the primary mechanism of bilirubin-induced neurologic dysfunction in jaundiced Gunn rat pups. |
2012 |
Pediatr. Res. |
pmid:22902434
|
Malo A et al. |
4-Phenylbutyric acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini. |
2013 |
Pancreas |
pmid:22889983
|
van Minnen LP et al. |
Cholesterol crystals enhance and phospholipids protect against pancreatitis induced by hydrophobic bile salts: a rat model study. |
2006 |
Pancreas |
pmid:16670619
|
Vandewynckel YP et al. |
Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure. |
2015 |
Oncotarget |
pmid:26293671
|
Jiao P et al. |
FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways. |
2011 |
Obesity (Silver Spring) |
pmid:20829802
|
Myronovych A et al. |
Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. |
2014 |
Obesity (Silver Spring) |
pmid:23804416
|
Zhang J et al. |
Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes. |
2016 |
Nutrients |
pmid:27669287
|
Kim GW et al. |
Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity. |
2016 |
Nutr Diabetes |
pmid:27214655
|
Hu J et al. |
Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23(erl/erl) mice. |
2016 |
Neuroscience |
pmid:26748055
|
Gaspar JM et al. |
Tauroursodeoxycholic acid protects retinal neural cells from cell death induced by prolonged exposure to elevated glucose. |
2013 |
Neuroscience |
pmid:24012838
|
Yan F et al. |
Endoplasmic reticulum stress is associated with neuroprotection against apoptosis via autophagy activation in a rat model of subarachnoid hemorrhage. |
2014 |
Neurosci. Lett. |
pmid:24513235
|
Lo AC et al. |
Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice. |
2013 |
Neurobiol. Dis. |
pmid:22974733
|
Ramalho RM et al. |
Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice. |
2013 |
Neurobiol. Aging |
pmid:22621777
|
Keestra-Gounder AM et al. |
NOD1 and NOD2 signalling links ER stress with inflammation. |
2016 |
Nature |
pmid:27007849
|
Bracha AL et al. |
Carbon metabolism-mediated myogenic differentiation. |
2010 |
Nat. Chem. Biol. |
pmid:20081855
|
Keune WJ et al. |
Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. |
2016 |
Nat Commun |
pmid:27075612
|
Fimognari C et al. |
Micronuclei induction, cell cycle delay and apoptosis as markers of cellular stress caused by ursodeoxycholic acid in human lymphocytes. |
2001 |
Mutat. Res. |
pmid:11448637
|
Udawatte C et al. |
Taurine suppresses the spread of cell death in electrically coupled RPE cells. |
2008 |
Mol. Vis. |
pmid:18958305
|
Boatright JH et al. |
Tool from ancient pharmacopoeia prevents vision loss. |
2006 |
Mol. Vis. |
pmid:17213800
|
Qi HP et al. |
Ursodeoxycholic acid prevents selenite-induced oxidative stress and alleviates cataract formation: In vitro and in vivo studies. |
2012 |
Mol. Vis. |
pmid:22275806
|
Zhou L et al. |
Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance. |
2009 |
Mol. Pharmacol. |
pmid:19541767
|
Vaidya SS and Gerk PM |
Lack of interaction between tauroursodeoxycholate and ATP-binding cassette transporter isoform G2 (ABCG2). |
2006 May-Jun |
Mol. Pharm. |
pmid:16749862
|
Castro-Caldas M et al. |
Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease. |
2012 |
Mol. Neurobiol. |
pmid:22773138
|
Nunes AF et al. |
TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice. |
2012 |
Mol. Neurobiol. |
pmid:22438081
|
Solá S et al. |
Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway. |
2003 Sep-Dec |
Mol. Med. |
pmid:15208744
|
Ramalho RM et al. |
Apoptosis in transgenic mice expressing the P301L mutated form of human tau. |
2008 May-Jun |
Mol. Med. |
pmid:18368144
|
Solá S et al. |
Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid beta-peptide-induced apoptosis. |
2006 |
Mol. Endocrinol. |
pmid:16728529
|
Penno CA et al. |
11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. |
2014 |
Mol Metab |
pmid:25061560
|
Nguyen LB et al. |
Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in the rat ileum: effects of bile acids and lovastatin. |
1994 |
Metab. Clin. Exp. |
pmid:7968602
|
Ma H et al. |
A multicenter, randomized, double-blind trial comparing the efficacy and safety of TUDCA and UDCA in Chinese patients with primary biliary cholangitis. |
2016 |
Medicine (Baltimore) |
pmid:27893675
|
Guo H et al. |
Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury. |
2016 |
Mediators Inflamm. |
pmid:27721575
|
Montagnani M et al. |
A new model for portal protein profile analysis in course of ileal intraluminal bile acid infusion using an in situ perfused rat intestine. |
2011 |
Med Chem |
pmid:21568879
|
Anderson CD et al. |
Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts. |
2011 |
Liver Transpl. |
pmid:21280192
|
Terry C et al. |
Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing. |
2005 |
Liver Transpl. |
pmid:16315306
|
Terry C et al. |
Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing. |
2006 |
Liver Transpl. |
pmid:16382475
|
Tsukahara K et al. |
Taurine conjugate of ursodeoxycholate plays a major role in the hepatoprotective effect against cholestasis induced by taurochenodeoxycholate in rats. |
1993 |
Liver |
pmid:8259039
|
Bouchard G et al. |
Influence of oral treatment with ursodeoxycholic and tauroursodeoxycholic acids on estrogen-induced cholestasis in rats: effects on bile formation and liver plasma membranes. |
1993 |
Liver |
pmid:8377596
|
Sánchez Pozzi EJ et al. |
Differential effect of ursodeoxycholate and its taurine conjugate on biliary transport maximum of bilirubin in the rat. |
1995 |
Life Sci. |
pmid:7643722
|
Lamireau T et al. |
Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. |
2003 |
Life Sci. |
pmid:12527037
|
López-Sánchez LM et al. |
Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis. |
2010 |
Lab. Invest. |
pmid:19806079
|
Dombrowski F et al. |
Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver. |
2006 |
Lab. Invest. |
pmid:16344857
|
Laukens D et al. |
Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death. |
2014 |
Lab. Invest. |
pmid:25310532
|
Kim HS et al. |
[Modulation of colon cancer cell invasiveness induced by deoxycholic acid]. |
2006 |
Korean J Gastroenterol |
pmid:16861876
|