| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Diabetes (3)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu Y et al. | Quercetin induces protective autophagy and apoptosis through ER stress via the p-STAT3/Bcl-2 axis in ovarian cancer. | 2017 | Apoptosis | pmid:28188387 |
| Fernández-Sánchez L et al. | Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats. | 2017 | PLoS ONE | pmid:28542454 |
| Rani S et al. | Tauroursodeoxycholic acid (TUDCA) attenuates pressure overload-induced cardiac remodeling by reducing endoplasmic reticulum stress. | 2017 | PLoS ONE | pmid:28426781 |
| Paridaens A et al. | Modulation of the Unfolded Protein Response by Tauroursodeoxycholic Acid Counteracts Apoptotic Cell Death and Fibrosis in a Mouse Model for Secondary Biliary Liver Fibrosis. | 2017 | Int J Mol Sci | pmid:28117681 |
| Xie C et al. | An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice. | 2017 | Diabetes | pmid:28223344 |
| Cheang WS et al. | PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice. | 2017 | Diabetes | pmid:27856609 |
| Guo Q et al. | Fibroblast growth factor 21 reverses suppression of adiponectin expression via inhibiting endoplasmic reticulum stress in adipose tissue of obese mice. | 2017 | Exp. Biol. Med. (Maywood) | pmid:27811171 |
| Contreras C et al. | Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity. | 2017 | Diabetes | pmid:27634226 |
| Zhang J et al. | Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation. | 2017 | Chem. Biol. Interact. | pmid:29031535 |
| Wong MK et al. | Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells. | 2016 | Toxicol. Sci. | pmid:26803847 |
| Keune WJ et al. | Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. | 2016 | Nat Commun | pmid:27075612 |
| Fu J et al. | Endoplasmic reticulum stress is involved in 2,4-dichlorophenol-induced hepatotoxicity. | 2016 | J Toxicol Sci | pmid:27853103 |
| Guo H et al. | Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury. | 2016 | Mediators Inflamm. | pmid:27721575 |
| Zhang J et al. | Tauroursodeoxycholic Acid Attenuates Renal Tubular Injury in a Mouse Model of Type 2 Diabetes. | 2016 | Nutrients | pmid:27669287 |
| Walsh LK et al. | Administration of tauroursodeoxycholic acid prevents endothelial dysfunction caused by an oral glucose load. | 2016 | Clin. Sci. | pmid:27503949 |
| Wei SG et al. | Endoplasmic reticulum stress increases brain MAPK signaling, inflammation and renin-angiotensin system activity and sympathetic nerve activity in heart failure. | 2016 | Am. J. Physiol. Heart Circ. Physiol. | pmid:27496879 |
| Groenendyk J et al. | Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis. | 2016 | PLoS ONE | pmid:27441395 |
| Yung HW et al. | Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants. | 2016 | Diabetologia | pmid:27406815 |
| Kim GW et al. | Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity. | 2016 | Nutr Diabetes | pmid:27214655 |
| Siddesha JM et al. | Effect of a chemical chaperone, tauroursodeoxycholic acid, on HDM-induced allergic airway disease. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27154200 |
| Memme JM et al. | Chronology of UPR activation in skeletal muscle adaptations to chronic contractile activity. | 2016 | Am. J. Physiol., Cell Physiol. | pmid:27122157 |
| Keestra-Gounder AM et al. | NOD1 and NOD2 signalling links ER stress with inflammation. | 2016 | Nature | pmid:27007849 |
| Flodby P et al. | The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. | 2016 | Am. J. Respir. Cell Mol. Biol. | pmid:26816051 |
| Ding W et al. | Involvement of Endoplasmic Reticulum Stress in Uremic Cardiomyopathy: Protective Effects of Tauroursodeoxycholic Acid. | 2016 | Cell. Physiol. Biochem. | pmid:26765262 |
| Hu J et al. | Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23(erl/erl) mice. | 2016 | Neuroscience | pmid:26748055 |
| Yang X et al. | Activation of autophagy by unfolded proteins during endoplasmic reticulum stress. | 2016 | Plant J. | pmid:26616142 |
| Zhou Q et al. | Effect of Tauroursodeoxycholic Acid and 4-Phenylbutyric Acid on Metabolism of Copper and Zinc in Type 1 Diabetic Mice Model. | 2016 | Biol Trace Elem Res | pmid:26282527 |
| Elia AE et al. | Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis. | 2016 | Eur. J. Neurol. | pmid:25664595 |
| Ma H et al. | A multicenter, randomized, double-blind trial comparing the efficacy and safety of TUDCA and UDCA in Chinese patients with primary biliary cholangitis. | 2016 | Medicine (Baltimore) | pmid:27893675 |
| Yang Z et al. | Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling. | 2015 | FEBS J. | pmid:25611565 |
| Tanaka Y et al. | The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice. | 2015 | Pharmacol. Res. | pmid:26005208 |
| Cortez LM et al. | Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease. | 2015 | J. Virol. | pmid:25972546 |
| Dubrey S et al. | The transthyretin amyloidoses: advances in therapy. | 2015 | Postgrad Med J | pmid:26048914 |
| Sommerfeld A et al. | Tauroursodeoxycholate Protects Rat Hepatocytes from Bile Acid-Induced Apoptosis via β1-Integrin- and Protein Kinase A-Dependent Mechanisms. | 2015 | Cell. Physiol. Biochem. | pmid:26044599 |
| Dong Y et al. | Neuroprotective effects and impact on caspase-12 expression of tauroursodeoxycholic acid after acute spinal cord injury in rats. | 2015 | Int J Clin Exp Pathol | pmid:26884858 |
| Shi Z et al. | [Tauroursodeoxycholic acid suppresses endoplasmic reticulum stress in pulmonary tissues of intermittent hypoxia mice]. | 2015 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:26643417 |
| Muramatsu-Kato K et al. | Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress. | 2015 | Sci Rep | pmid:26581663 |
| Gómez-Vicente V et al. | Neuroprotective Effect of Tauroursodeoxycholic Acid on N-Methyl-D-Aspartate-Induced Retinal Ganglion Cell Degeneration. | 2015 | PLoS ONE | pmid:26379056 |
| Vandewynckel YP et al. | Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure. | 2015 | Oncotarget | pmid:26293671 |
| Koyama S et al. | Gefitinib and Erlotinib Lead to Phosphorylation of Eukaryotic Initiation Factor 2 Alpha Independent of Epidermal Growth Factor Receptor in A549 Cells. | 2015 | PLoS ONE | pmid:26288223 |
| Yu KN et al. | Titanium Dioxide Nanoparticles Induce Endoplasmic Reticulum Stress-Mediated Autophagic Cell Death via Mitochondria-Associated Endoplasmic Reticulum Membrane Disruption in Normal Lung Cells. | 2015 | PLoS ONE | pmid:26121477 |
| Bikbova G et al. | Altered Expression of NF- κ B and SP1 after Exposure to Advanced Glycation End-Products and Effects of Neurotrophic Factors in AGEs Exposed Rat Retinas. | 2015 | J Diabetes Res | pmid:26078979 |
| Cai Z et al. | Involvement of Endoplasmic Reticulum Stress-Mediated C/EBP Homologous Protein Activation in Coxsackievirus B3-Induced Acute Viral Myocarditis. | 2015 | Circ Heart Fail | pmid:25985795 |
| Oishi N et al. | XBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death. | 2015 | Cell Death Dis | pmid:25973683 |
| Cheng S et al. | Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stress. | 2015 | PLoS ONE | pmid:25915041 |
| Xu LH et al. | Critical Role of Endoplasmic Reticulum Stress in Chronic Intermittent Hypoxia-Induced Deficits in Synaptic Plasticity and Long-Term Memory. | 2015 | Antioxid. Redox Signal. | pmid:25843188 |
| Liu F et al. | Tauroursodeoxycholic acid attenuates inorganic phosphate-induced osteoblastic differentiation and mineralization in NIH3T3 fibroblasts by inhibiting the ER stress response PERK-eIF2α-ATF4 pathway. | 2015 | Drug Discov Ther | pmid:25788050 |
| Xia H et al. | Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress. | 2015 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:25519733 |
| Shi Z et al. | Vasonatrin peptide attenuates myocardial ischemia-reperfusion injury in diabetic rats and underlying mechanisms. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:25485902 |
| Cho JG et al. | Tauroursodeoxycholic acid, a bile acid, promotes blood vessel repair by recruiting vasculogenic progenitor cells. | 2015 | Stem Cells | pmid:25407160 |
| Hakim F et al. | Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice. | 2015 | Sleep | pmid:25325461 |
| Oshitari T et al. | Increased expression of phosphorylated c-Jun and phosphorylated c-Jun N-terminal kinase associated with neuronal cell death in diabetic and high glucose exposed rat retinas. | 2014 | Brain Res. Bull. | pmid:24333191 |
| Shen S et al. | Ursolic acid induces autophagy in U87MG cells via ROS-dependent endoplasmic reticulum stress. | 2014 | Chem. Biol. Interact. | pmid:24802810 |
| Lee ES et al. | Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24973711 |
| Penno CA et al. | 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. | 2014 | Mol Metab | pmid:25061560 |
| Cheng X et al. | Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum. | 2014 | J. Pharmacol. Exp. Ther. | pmid:25034404 |
| Cho EJ et al. | Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine-choline-deficient diet. | 2014 | Dig. Dis. Sci. | pmid:24865256 |
| Xavier JM et al. | Tauroursodeoxycholic acid increases neural stem cell pool and neuronal conversion by regulating mitochondria-cell cycle retrograde signaling. | 2014 | Cell Cycle | pmid:25483094 |
| Ishimura S et al. | Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury. | 2014 | Sci Rep | pmid:25373918 |
| Noailles A et al. | Microglia activation in a model of retinal degeneration and TUDCA neuroprotective effects. | 2014 | J Neuroinflammation | pmid:25359524 |
| Yan F et al. | Endoplasmic reticulum stress is associated with neuroprotection against apoptosis via autophagy activation in a rat model of subarachnoid hemorrhage. | 2014 | Neurosci. Lett. | pmid:24513235 |
| Laukens D et al. | Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death. | 2014 | Lab. Invest. | pmid:25310532 |
| Park SW et al. | Rab11, but not Rab4, facilitates cyclic AMP- and tauroursodeoxycholate-induced MRP2 translocation to the plasma membrane. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25190474 |
| van der Harg JM et al. | The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress. | 2014 | Cell Death Dis | pmid:25165879 |
| Debattisti V et al. | Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion. | 2014 | J. Cell Biol. | pmid:24469638 |
| Yanguas-Casás N et al. | Tauroursodeoxycholic acid reduces glial cell activation in an animal model of acute neuroinflammation. | 2014 | J Neuroinflammation | pmid:24645669 |
| Cha BH et al. | The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress. | 2014 | Biomaterials | pmid:24424209 |
| Fu Y and Zhang T | Pathophysilogical mechanism and treatment strategies for Leber congenital amaurosis. | 2014 | Adv. Exp. Med. Biol. | pmid:24664772 |
| Myronovych A et al. | Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. | 2014 | Obesity (Silver Spring) | pmid:23804416 |
| Hamano M et al. | Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis. | 2014 | J. Gastroenterol. | pmid:23512345 |
| Simoni P et al. | A new point-of-care portable immunosensor for non-invasive assessment of oro-ileal transit time by oral fluid tauroursodeoxycholate measurement after its oral load. | 2013 Jul-Aug | J Pharm Biomed Anal | pmid:23587552 |
| Spitler KM et al. | Suppression of endoplasmic reticulum stress improves endothelium-dependent contractile responses in aorta of the spontaneously hypertensive rat. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23709602 |
| Dikkers A et al. | Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice. | 2013 | Hepatology | pmid:23401258 |
| Gohlke H et al. | α5 β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes. | 2013 | Hepatology | pmid:22865233 |
| Wang R et al. | Defective canalicular transport and toxicity of dietary ursodeoxycholic acid in the abcb11-/- mouse: transport and gene expression studies. | 2013 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:23764895 |
| Pan XL et al. | Efficacy and safety of tauroursodeoxycholic acid in the treatment of liver cirrhosis: a double-blind randomized controlled trial. | 2013 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:23592128 |
| Kim KS et al. | Taurine may not alleviate hyperglycemia-mediated endoplasmic reticulum stress in human adipocytes. | 2013 | Adv. Exp. Med. Biol. | pmid:23392949 |
| Shin J et al. | SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease. | 2013 | Cell Rep | pmid:24210820 |
| Belaidi E et al. | Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition. | 2013 | Basic Res. Cardiol. | pmid:23744057 |
| Ramalho RM et al. | Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice. | 2013 | Neurobiol. Aging | pmid:22621777 |
| Zhu Q et al. | Tauroursodeoxycholate, a chemical chaperone, prevents palmitate-induced apoptosis in pancreatic β-cells by reducing ER stress. | 2013 | Exp. Clin. Endocrinol. Diabetes | pmid:22972029 |
| Lo AC et al. | Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice. | 2013 | Neurobiol. Dis. | pmid:22974733 |
| Schulz S et al. | Progressive stages of mitochondrial destruction caused by cell toxic bile salts. | 2013 | Biochim. Biophys. Acta | pmid:23685124 |
| Malo A et al. | 4-Phenylbutyric acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini. | 2013 | Pancreas | pmid:22889983 |
| Omura T et al. | Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23416354 |
| Beuers U | β1 integrin is a long-sought sensor for tauroursodeoxycholic acid. | 2013 | Hepatology | pmid:23456677 |
| Fang L et al. | Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. | 2013 | PLoS ONE | pmid:23593240 |
| Turdi S et al. | Tauroursodeoxycholic acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular Ca2+ anomalies. | 2013 | PLoS ONE | pmid:23667647 |
| Liang B et al. | Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23288166 |
| Dromparis P et al. | Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension. | 2013 | Circulation | pmid:23149668 |
| Panzhinskiy E et al. | Endoplasmic reticulum stress upregulates protein tyrosine phosphatase 1B and impairs glucose uptake in cultured myotubes. | 2013 | Diabetologia | pmid:23178931 |
| Yao XH et al. | Prenatal ethanol exposure causes glucose intolerance with increased hepatic gluconeogenesis and histone deacetylases in adult rat offspring: reversal by tauroursodeoxycholic acid. | 2013 | PLoS ONE | pmid:23544086 |
| Zhang J et al. | Autophagy is involved in endoplasmic reticulum stress-induced cell death of rat hepatocytes. | 2013 | J. Surg. Res. | pmid:23548375 |
| Mitra A et al. | Role of α-crystallin B as a regulatory switch in modulating cardiomyocyte apoptosis by mitochondria or endoplasmic reticulum during cardiac hypertrophy and myocardial infarction. | 2013 | Cell Death Dis | pmid:23559016 |
| Cai Z et al. | Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23928865 |
| Mališová L et al. | Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes. | 2013 | PLoS ONE | pmid:24312631 |
| Gaspar JM et al. | Tauroursodeoxycholic acid protects retinal neural cells from cell death induced by prolonged exposure to elevated glucose. | 2013 | Neuroscience | pmid:24012838 |
| Takeda N et al. | Altered unfolded protein response is implicated in the age-related exacerbation of proteinuria-induced proximal tubular cell damage. | 2013 | Am. J. Pathol. | pmid:23871833 |
| Kohli R et al. | A surgical model in male obese rats uncovers protective effects of bile acids post-bariatric surgery. | 2013 | Endocrinology | pmid:23592746 |
| Fang L et al. | Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells. | 2013 | PLoS ONE | pmid:23977286 |