| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Diabetes (3)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim JK | Inflammation and insulin resistance: an old story with new ideas. | 2010 | Korean Diabetes J | pmid:20617073 |
| Dong Y et al. | Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. | 2010 | Circulation | pmid:20124121 |
| Ceylan-Isik AF et al. | Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis. | 2010 | J. Mol. Cell. Cardiol. | pmid:19914257 |
| Ye R et al. | Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance. | 2010 | Diabetes | pmid:19808896 |
| Lim SC et al. | Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma. | 2010 | Int. J. Cancer | pmid:19728331 |
| Basiglio CL et al. | Tauroursodeoxycholate counteracts hepatocellular lysis induced by tensioactive bile salts by preventing plasma membrane-micelle transition. | 2010 | Chem. Biol. Interact. | pmid:20797393 |
| Fulda S et al. | Cellular stress responses: cell survival and cell death. | 2010 | Int J Cell Biol | pmid:20182529 |
| Malo A et al. | Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20671193 |
| Cardoso I et al. | Synergy of combined doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models. | 2010 | J Transl Med | pmid:20673327 |
| Bracha AL et al. | Carbon metabolism-mediated myogenic differentiation. | 2010 | Nat. Chem. Biol. | pmid:20081855 |
| López-Sánchez LM et al. | Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis. | 2010 | Lab. Invest. | pmid:19806079 |
| Cruz LN et al. | Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver. | 2010 | Hepatology | pmid:20578149 |
| Kars M et al. | Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. | 2010 | Diabetes | pmid:20522594 |
| Viana RJ et al. | Modulation of amyloid-β peptide-induced toxicity through inhibition of JNK nuclear localization and caspase-2 activation. | 2010 | J. Alzheimers Dis. | pmid:20847398 |
| Hua Y et al. | Tauroursodeoxycholic acid attenuates lipid accumulation in endoplasmic reticulum-stressed macrophages. | 2010 | J. Cardiovasc. Pharmacol. | pmid:19834331 |
| Ben Mosbah I et al. | Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion. | 2010 | Cell Death Dis | pmid:21364657 |
| Schmidt DR et al. | Regulation of bile acid synthesis by fat-soluble vitamins A and D. | 2010 | J. Biol. Chem. | pmid:20233723 |
| Hohenester S et al. | Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells. | 2010 | J. Hepatol. | pmid:20675006 |
| RodrÃguez-Ortigosa CM et al. | Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat. | 2010 | Hepatology | pmid:20683964 |
| Woo SJ et al. | Ursodeoxycholic acid and tauroursodeoxycholic acid suppress choroidal neovascularization in a laser-treated rat model. | 2010 | J Ocul Pharmacol Ther | pmid:20565307 |