| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Diabetes (3)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shen S et al. | Ursolic acid induces autophagy in U87MG cells via ROS-dependent endoplasmic reticulum stress. | 2014 | Chem. Biol. Interact. | pmid:24802810 |
| Lee ES et al. | Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24973711 |
| Penno CA et al. | 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. | 2014 | Mol Metab | pmid:25061560 |
| Cheng X et al. | Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum. | 2014 | J. Pharmacol. Exp. Ther. | pmid:25034404 |
| Cho EJ et al. | Tauroursodeoxycholic acid attenuates progression of steatohepatitis in mice fed a methionine-choline-deficient diet. | 2014 | Dig. Dis. Sci. | pmid:24865256 |
| Xavier JM et al. | Tauroursodeoxycholic acid increases neural stem cell pool and neuronal conversion by regulating mitochondria-cell cycle retrograde signaling. | 2014 | Cell Cycle | pmid:25483094 |
| Ishimura S et al. | Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury. | 2014 | Sci Rep | pmid:25373918 |
| Debattisti V et al. | Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion. | 2014 | J. Cell Biol. | pmid:24469638 |
| Myronovych A et al. | Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. | 2014 | Obesity (Silver Spring) | pmid:23804416 |
| Hamano M et al. | Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis. | 2014 | J. Gastroenterol. | pmid:23512345 |
| Simoni P et al. | A new point-of-care portable immunosensor for non-invasive assessment of oro-ileal transit time by oral fluid tauroursodeoxycholate measurement after its oral load. | 2013 Jul-Aug | J Pharm Biomed Anal | pmid:23587552 |
| Pan XL et al. | Efficacy and safety of tauroursodeoxycholic acid in the treatment of liver cirrhosis: a double-blind randomized controlled trial. | 2013 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:23592128 |
| Belaidi E et al. | Endoplasmic reticulum stress contributes to heart protection induced by cyclophilin D inhibition. | 2013 | Basic Res. Cardiol. | pmid:23744057 |
| Omura T et al. | Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23416354 |
| Beuers U | β1 integrin is a long-sought sensor for tauroursodeoxycholic acid. | 2013 | Hepatology | pmid:23456677 |
| Cai Z et al. | Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23928865 |
| Gaspar JM et al. | Tauroursodeoxycholic acid protects retinal neural cells from cell death induced by prolonged exposure to elevated glucose. | 2013 | Neuroscience | pmid:24012838 |
| Xu H et al. | The ER luminal binding protein (BiP) alleviates Cd(2+)-induced programmed cell death through endoplasmic reticulum stress-cell death signaling pathway in tobacco cells. | 2013 | J. Plant Physiol. | pmid:23867017 |
| Takeda N et al. | Altered unfolded protein response is implicated in the age-related exacerbation of proteinuria-induced proximal tubular cell damage. | 2013 | Am. J. Pathol. | pmid:23871833 |
| Fang L et al. | Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells. | 2013 | PLoS ONE | pmid:23977286 |