| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Watt SM and Simmonds WJ | Effects of four taurine-conjugated bile acids on mucosal uptake and lymphatic absorption of cholesterol in the rat. | 1984 | J. Lipid Res. | pmid:6736779 |
| Stiehl A et al. | Effect of ursodeoxycholic acid on biliary bile acid and bile lipid composition in gallstone patients. | 1984 Jan-Feb | Hepatology | pmid:6693062 |
| Hofmann AF | Medical treatment of cholesterol gallstones by bile desaturating agents. | 1984 Sep-Oct | Hepatology | pmid:6384003 |
| Garcia-Marin JJ et al. | Role of H+ transport in ursodeoxycholate-induced biliary HCO-3 secretion in the rat. | 1985 | Am. J. Physiol. | pmid:2994491 |
| Eto T and Tompkins RK | Inhibition of pepsin activity by ursodeoxycholic acids and chenodeoxycholic acids. | 1985 | Am. J. Surg. | pmid:3933371 |
| Walker S et al. | Absorption of urso- and chenodeoxycholic acid and their taurine and glycine conjugates in rat jejunum, ileum, and colon. | 1985 | Digestion | pmid:4018444 |
| Kitani K et al. | Tauroursodeoxycholate prevents biliary protein excretion induced by other bile salts in the rat. | 1985 | Am. J. Physiol. | pmid:2984943 |
| Kitani K et al. | Differing transport maxima values for taurine-conjugated bile salts in rats and hamsters. | 1986 | Am. J. Physiol. | pmid:3789151 |
| Alvaro D et al. | Influence of tauroursodeoxycholic and taurodeoxycholic acids on hepatic metabolism and biliary secretion of phosphatidylcholine in the isolated rat liver. | 1986 | Biochim. Biophys. Acta | pmid:3756193 |
| Marteau C et al. | Effect of various bile salts on calcium concentration and calcium carbonate saturation of rat bile. | 1988 | J. Hepatol. | pmid:3183351 |
| Aldini R et al. | Uptake of bile acids by perfused rat liver: evidence of a structure-activity relationship. | 1989 | Hepatology | pmid:2807164 |
| Farges O et al. | Permeability of the rat biliary tree to ursodeoxycholic acid. | 1989 | Am. J. Physiol. | pmid:2705526 |
| Schmucker DL et al. | Hepatic injury induced by bile salts: correlation between biochemical and morphological events. | 1990 | Hepatology | pmid:2227821 |
| Schölmerich J et al. | Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver. | 1990 | J. Hepatol. | pmid:2365980 |
| Perez Barriocanal F et al. | Influence of backward perfusion on ursodeoxycholate-induced choleresis in isolated in situ rat liver. | 1990 | J. Hepatol. | pmid:2254627 |
| Zhao XM and Montet JC | Effects of bile salt supplementation on biliary secretion in estrogen-treated rats. | 1990 | J. Nutr. Biochem. | pmid:15539232 |
| Beuers U et al. | Tauroursodeoxycholic acid inhibits the cytosolic Ca++ increase in human neutrophils stimulated by formyl-methionyl-leucyl-phenylalanine. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2222431 |
| Utili R et al. | Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts. | 1990 | Hepatology | pmid:2347547 |
| Chazouillères O et al. | Effect of bile acids on ischemia-reperfusion liver injury. | 1991 | J. Hepatol. | pmid:1808225 |
| Deroubaix X et al. | Saturation of hepatic transport of taurocholate in rats in vivo. | 1991 | Am. J. Physiol. | pmid:1996639 |