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Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione. |
2001 |
Hepatology |
pmid:11679967
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Heubi JE et al. |
Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease. |
2002 |
J. Pediatr. |
pmid:12183720
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Duan WM et al. |
Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease. |
2002 |
Cell Transplant |
pmid:12075985
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Xiao ZL et al. |
Effects of bile acids on the muscle functions of guinea pig gallbladder. |
2002 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12065295
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Glasova H et al. |
Tauroursodeoxycholic acid mobilizes alpha-PKC after uptake in human HepG2 hepatoma cells. |
2002 |
Eur. J. Clin. Invest. |
pmid:12059989
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Noé J et al. |
Functional expression of the canalicular bile salt export pump of human liver. |
2002 |
Gastroenterology |
pmid:12404240
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Piepoli AL et al. |
Tauroursodeoxycholic acid reduces damaging effects of taurodeoxycholic acid on fundus gastric mucosa. |
2002 |
Arch. Physiol. Biochem. |
pmid:12221520
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Pandak WM et al. |
Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes. |
2002 |
Hepatology |
pmid:12029625
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Azzaroli F et al. |
Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes. |
2002 |
Hepatology |
pmid:12085348
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Milkiewicz P et al. |
Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways. |
2002 |
Gut |
pmid:12077103
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Graf D et al. |
Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. |
2002 |
Gastroenterology |
pmid:11984527
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Yamashita Y et al. |
High metabolic function of primary human and porcine hepatocytes in a polyurethane foam/spheroid culture system in plasma from patients with fulminant hepatic failure. |
2002 |
Cell Transplant |
pmid:12162378
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Veggi LM et al. |
Dapsone-induced cholestasis and impairment of bile salt output in the rat. |
2002 |
Biochem. Pharmacol. |
pmid:11996898
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Kim YH and Shin MJ |
Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes. |
2002 |
Exp. Mol. Med. |
pmid:12085987
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Neuroprotection by a bile acid in an acute stroke model in the rat. |
2002 |
J. Cereb. Blood Flow Metab. |
pmid:11919517
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Carubbi F et al. |
Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line. |
2002 |
Biochim. Biophys. Acta |
pmid:11923098
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Xie Q et al. |
Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. |
2002 |
Hepatology |
pmid:12198651
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Venneman NG et al. |
Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles. |
2002 |
Biochim. Biophys. Acta |
pmid:12117566
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Keene CD et al. |
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12149470
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Alpini G et al. |
Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha. |
2002 |
Hepatology |
pmid:11981754
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Kok T et al. |
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice. |
2003 |
Biochem. J. |
pmid:12381268
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Rodrigues CM et al. |
Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria. |
2003 |
Biochemistry |
pmid:12627974
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Rodrigues CM et al. |
Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12721362
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Häussinger D et al. |
Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis. |
2003 |
Gastroenterology |
pmid:12730886
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Baiocchi L et al. |
Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats. |
2003 |
J. Hepatol. |
pmid:12547401
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Chen W et al. |
Bile acids for viral hepatitis. |
2003 |
Cochrane Database Syst Rev |
pmid:12804455
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Chignard N et al. |
Bile salts potentiate adenylyl cyclase activity and cAMP-regulated secretion in human gallbladder epithelium. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12421748
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Tessier E et al. |
High-performance liquid chromatographic mass spectrometric method for the determination of ursodeoxycholic acid and its glycine and taurine conjugates in human plasma. |
2003 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:14643509
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Schoemaker MH et al. |
Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation. |
2003 |
J. Hepatol. |
pmid:12873810
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Komichi D et al. |
Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes. |
2003 |
Dig. Dis. Sci. |
pmid:14714619
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Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets. |
2003 |
J. Biol. Chem. |
pmid:12626520
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Reinehr R et al. |
Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation. |
2003 |
Gastroenterology |
pmid:12949729
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Ma J et al. |
Inhibitory effects of ursodeoxycholic acid on the induction of nitric oxide synthase in vascular smooth muscle cells. |
2003 |
Eur. J. Pharmacol. |
pmid:12620498
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Tsuboi K et al. |
Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity. |
2003 |
Hepatol. Res. |
pmid:12644037
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Sánchez Pozzi EJ et al. |
Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12663690
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Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion. |
2003 |
Life Sci. |
pmid:12527037
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Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis. |
2003 |
J. Clin. Invest. |
pmid:14623915
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Solá S et al. |
Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway. |
2003 Sep-Dec |
Mol. Med. |
pmid:15208744
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Castro RE et al. |
The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons. |
2004 |
J. Pharmacol. Exp. Ther. |
pmid:15190125
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Ramalho RM et al. |
Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 cells. |
2004 |
J. Neurochem. |
pmid:15255934
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Kubitz R et al. |
Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase. |
2004 |
Gastroenterology |
pmid:14762791
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Solá S et al. |
Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes. |
2004 |
Biochemistry |
pmid:15222754
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Klett EL et al. |
A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. |
2004 |
BMC Med |
pmid:15040800
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Schoemaker MH et al. |
Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways. |
2004 |
Hepatology |
pmid:15185297
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Lee DK et al. |
[Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8]. |
2004 |
Korean J Gastroenterol |
pmid:15034288
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Henzel K et al. |
Toxicity of ethanol and acetaldehyde in hepatocytes treated with ursodeoxycholic or tauroursodeoxycholic acid. |
2004 |
Biochim. Biophys. Acta |
pmid:14741743
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Ma J et al. |
Ursodeoxycholic acid inhibits endothelin-1 production in human vascular endothelial cells. |
2004 |
Eur. J. Pharmacol. |
pmid:15556138
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Marumo T et al. |
Biliary excretion of bile acids and organic anions in rats with dichloroethylene-induced bile canalicular injury. |
2004 |
J. Gastroenterol. |
pmid:15549452
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Rolo AP et al. |
Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis. |
2004 |
Toxicol. Sci. |
pmid:14976352
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Tachizawa H et al. |
Effects of colchicine on the maximum biliary excretion of cholephilic compounds in rats. |
2004 |
J. Gastroenterol. Hepatol. |
pmid:15304119
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