| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Diabetes (3)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ramalho RM et al. | Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice. | 2013 | Neurobiol. Aging | pmid:22621777 |
| Balasubramanyam M et al. | Molecular intricacies and the role of ER stress in diabetes. | 2012 | Exp Diabetes Res | pmid:22701473 |
| Lenin R et al. | Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a "chemical chaperone" in human THP-1 monocytes. | 2012 | Exp Diabetes Res | pmid:22550476 |
| Xu J et al. | Endoplasmic reticulum stress and diabetic cardiomyopathy. | 2012 | Exp Diabetes Res | pmid:22144992 |
| Matsubara T et al. | TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. | 2012 | J. Lipid Res. | pmid:23034213 |
| Drack AV et al. | TUDCA slows retinal degeneration in two different mouse models of retinitis pigmentosa and prevents obesity in Bardet-Biedl syndrome type 1 mice. | 2012 | Invest. Ophthalmol. Vis. Sci. | pmid:22110077 |
| Amin A et al. | Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice. | 2012 | J. Pathol. | pmid:22081301 |
| Fonseca MB et al. | c-Jun regulates the stability of anti-apoptotic ΔNp63 in amyloid-β-induced apoptosis. | 2012 | J. Alzheimers Dis. | pmid:22045494 |
| Studer E et al. | Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. | 2012 | Hepatology | pmid:21932398 |
| Brites D | The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation. | 2012 | Front Pharmacol | pmid:22661946 |
| Farrell GC et al. | NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications. | 2012 | Gut Liver | pmid:22570745 |
| Hassan IH et al. | Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. | 2012 | J. Biol. Chem. | pmid:22194594 |
| Rieusset J et al. | Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22177958 |
| Cash JG et al. | Apolipoprotein E4 impairs macrophage efferocytosis and potentiates apoptosis by accelerating endoplasmic reticulum stress. | 2012 | J. Biol. Chem. | pmid:22730380 |
| Zhang JY et al. | Inhibition of endoplasmic reticulum stress improves mouse embryo development. | 2012 | PLoS ONE | pmid:22808162 |
| Galán M et al. | A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus. | 2012 | Hypertension | pmid:22665120 |
| Young CN et al. | ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension. | 2012 | J. Clin. Invest. | pmid:23064361 |
| Henkel AS et al. | Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22556147 |
| Daood MJ et al. | Lipid peroxidation is not the primary mechanism of bilirubin-induced neurologic dysfunction in jaundiced Gunn rat pups. | 2012 | Pediatr. Res. | pmid:22902434 |
| Cheng F et al. | Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. | 2012 | Evid Based Complement Alternat Med | pmid:22536287 |