| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Elanchezhian R et al. | Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells. | 2012 | Cell Death Dis | pmid:22513875 |
| Ma Y et al. | Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium. | 2012 | PLoS ONE | pmid:22493744 |
| Beriault DR and Werstuck GH | The role of glucosamine-induced ER stress in diabetic atherogenesis. | 2012 | Exp Diabetes Res | pmid:22474416 |
| Cai D and Liu T | Inflammatory cause of metabolic syndrome via brain stress and NF-κB. | 2012 | Aging (Albany NY) | pmid:22328600 |
| Nguyen MT et al. | Regulation of chemokine and chemokine receptor expression by PPARγ in adipocytes and macrophages. | 2012 | PLoS ONE | pmid:22529965 |
| Achard CS and Laybutt DR | Lipid-induced endoplasmic reticulum stress in liver cells results in two distinct outcomes: adaptation with enhanced insulin signaling or insulin resistance. | 2012 | Endocrinology | pmid:22374970 |
| Cursio R and Gugenheim J | Ischemia-Reperfusion Injury and Ischemic-Type Biliary Lesions following Liver Transplantation. | 2012 | J Transplant | pmid:22530107 |
| Obici L et al. | Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study. | 2012 | Amyloid | pmid:22551192 |
| Zhang T et al. | Chemical chaperone TUDCA preserves cone photoreceptors in a mouse model of Leber congenital amaurosis. | 2012 | Invest. Ophthalmol. Vis. Sci. | pmid:22531707 |
| Jiménez-Castro MB et al. | Tauroursodeoxycholic acid affects PPARγ and TLR4 in Steatotic liver transplantation. | 2012 | Am. J. Transplant. | pmid:22994543 |
| Zhang JY et al. | Effect of endoplasmic reticulum stress on porcine oocyte maturation and parthenogenetic embryonic development in vitro. | 2012 | Biol. Reprod. | pmid:22190710 |
| Younce C and Kolattukudy P | MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy. | 2012 | Cell. Physiol. Biochem. | pmid:22739135 |
| Roy A and Kolattukudy PE | Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy. | 2012 | Cell. Signal. | pmid:22820500 |
| Zhang Y et al. | Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury. | 2012 | Toxicol. Sci. | pmid:22461449 |
| Castro-Caldas M et al. | Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease. | 2012 | Mol. Neurobiol. | pmid:22773138 |
| Nunes AF et al. | TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice. | 2012 | Mol. Neurobiol. | pmid:22438081 |
| Tang C et al. | Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress. | 2012 | Diabetologia | pmid:22396011 |
| van Heumen BW et al. | Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells. | 2012 | Exp. Cell Res. | pmid:22366264 |
| Min JH et al. | Oral solubilized ursodeoxycholic acid therapy in amyotrophic lateral sclerosis: a randomized cross-over trial. | 2012 | J. Korean Med. Sci. | pmid:22323869 |
| Cheng F et al. | Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. | 2012 | Evid Based Complement Alternat Med | pmid:22536287 |