| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Amaral JD et al. | p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. | 2007 | J. Biol. Chem. | pmid:17881359 |
| Sheu ML et al. | Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth. | 2007 | PLoS ONE | pmid:17971859 |
| Wei H et al. | ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones. | 2008 | Hum. Mol. Genet. | pmid:17989065 |
| Watanabe N and Lam E | BAX inhibitor-1 modulates endoplasmic reticulum stress-mediated programmed cell death in Arabidopsis. | 2008 | J. Biol. Chem. | pmid:18039663 |
| Chazouillères O et al. | Effect of bile acids on ischemia-reperfusion liver injury. | 1991 | J. Hepatol. | pmid:1808225 |
| Pusl T et al. | Tauroursodeoxycholic acid reduces bile acid-induced apoptosis by modulation of AP-1. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18164257 |
| Lawless MW et al. | Tauroursodeoxycholic acid: relieving the pathogenesis of HFE C282Y hereditary hemochromatosis. | 2008 | Hepatology | pmid:18203149 |
| Mannack G et al. | Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver. | 2008 | Cell. Physiol. Biochem. | pmid:18209481 |
| Ramalho RM et al. | Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. | 2008 | Trends Mol Med | pmid:18218342 |
| Colak A et al. | Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats. | 2008 | J Clin Neurosci | pmid:18343118 |
| Ramalho RM et al. | Apoptosis in transgenic mice expressing the P301L mutated form of human tau. | 2008 May-Jun | Mol. Med. | pmid:18368144 |
| Baiocchi L et al. | TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway. | 2008 | Transpl. Int. | pmid:18435680 |
| Phillips MJ et al. | Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30. | 2008 | Invest. Ophthalmol. Vis. Sci. | pmid:18436848 |
| Monte MJ et al. | Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18467501 |
| Park IH et al. | Ursodeoxycholic acid prevents apoptosis of mouse sensory neurons induced by cisplatin by reducing P53 accumulation. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18558085 |
| Macedo B et al. | Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy. | 2008 | Biochim. Biophys. Acta | pmid:18572024 |
| Wimmer R et al. | Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver. | 2008 | Gut | pmid:18583398 |
| Chen Y et al. | Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes. | 2008 | Am. J. Nephrol. | pmid:18648192 |
| Udawatte C et al. | Taurine suppresses the spread of cell death in electrically coupled RPE cells. | 2008 | Mol. Vis. | pmid:18958305 |
| Roma MG et al. | Dynamic localization of hepatocellular transporters in health and disease. | 2008 | World J. Gastroenterol. | pmid:19058304 |