| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
Total
2
Tauroursodeoxycholic acid
Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.
Cross Reference
Introduction
To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tauroursodeoxycholic acid?
Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Diabetes (3)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
- Others (5)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid
PubChem Associated disorders and diseases
What pathways are associated with Tauroursodeoxycholic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tauroursodeoxycholic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tauroursodeoxycholic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Tauroursodeoxycholic acid?
Disease model
Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Tauroursodeoxycholic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Basseri S and Austin RC | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. | 2012 | Biochem Res Int | pmid:22195283 |
| Kim JS et al. | Tauroursodeoxycholic acid enhances the pre-implantation embryo development by reducing apoptosis in pigs. | 2012 | Reprod. Domest. Anim. | pmid:22151574 |
| Zhang JY et al. | Effect of endoplasmic reticulum stress on porcine oocyte maturation and parthenogenetic embryonic development in vitro. | 2012 | Biol. Reprod. | pmid:22190710 |
| Gao X et al. | The nephroprotective effect of tauroursodeoxycholic acid on ischaemia/reperfusion-induced acute kidney injury by inhibiting endoplasmic reticulum stress. | 2012 | Basic Clin. Pharmacol. Toxicol. | pmid:22212133 |
| van Heumen BW et al. | Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells. | 2012 | Exp. Cell Res. | pmid:22366264 |
| Qi HP et al. | Ursodeoxycholic acid prevents selenite-induced oxidative stress and alleviates cataract formation: In vitro and in vivo studies. | 2012 | Mol. Vis. | pmid:22275806 |
| Min JH et al. | Oral solubilized ursodeoxycholic acid therapy in amyotrophic lateral sclerosis: a randomized cross-over trial. | 2012 | J. Korean Med. Sci. | pmid:22323869 |
| Bodewes FA et al. | Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in mice. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22301109 |
| Trottier J et al. | Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. | 2011 | PLoS ONE | pmid:21760958 |
| Leong ML et al. | Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain. | 2011 | J. Neurosci. | pmid:22114272 |
| Sökmen HM et al. | Situs inversus totalis and secondary biliary cirrhosis: a case report. | 2011 | Comp Hepatol | pmid:21813017 |
| Qiao X et al. | Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. | 2011 | J Chromatogr A | pmid:21111425 |
| Megaraj V et al. | Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2). | 2011 | Pharmacogenet. Genomics | pmid:21691255 |
| Fernández-Sánchez L et al. | Tauroursodeoxycholic acid prevents retinal degeneration in transgenic P23H rats. | 2011 | Invest. Ophthalmol. Vis. Sci. | pmid:21508111 |
| Berger E and Haller D | Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21605547 |
| Montagnani M et al. | A new model for portal protein profile analysis in course of ileal intraluminal bile acid infusion using an in situ perfused rat intestine. | 2011 | Med Chem | pmid:21568879 |
| Viana RJ et al. | Amyloid-β peptide-induced secretion of endoplasmic reticulum chaperone glycoprotein GRP94. | 2011 | J. Alzheimers Dis. | pmid:21750376 |
| Seyhun E et al. | Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis. | 2011 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:21778463 |
| Kim SY et al. | Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK via PKCα-mediated MKP-1 induction. | 2011 | Cardiovasc. Res. | pmid:21840882 |
| Mantopoulos D et al. | Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. | 2011 | PLoS ONE | pmid:21961034 |