2-propyl-2-pentenoic acid

2-propyl-2-pentenoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 111 references associated with 2-propyl-2-pentenoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Aires CC et al. Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes. 2008 FEBS Lett. pmid:18775709
Eyal S et al. Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives. 2005 Biochem. Pharmacol. pmid:15857614
Silva MF et al. Differential effect of valproate and its Delta2- and Delta4-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids. 2001 Chem. Biol. Interact. pmid:11566289
Wong H et al. Ontogeny of valproic acid disposition and metabolism: a developmental study in postnatal lambs and adult sheep. 2000 Drug Metab. Dispos. pmid:10901700
Sokolova S et al. Comparison of effects of valproate and trans-2-en-valproate on different forms of epileptiform activity in rat hippocampal and temporal cortex slices. 1998 Epilepsia pmid:9578041
Scism JL et al. Effects of probenecid on brain-cerebrospinal fluid-blood distribution kinetics of E-Delta 2-valproic acid in rabbits. 1997 Drug Metab. Dispos. pmid:9394022
Wamil AW et al. Trans-2-en-valproic acid limits action potential firing frequency in mouse central neurons in cell culture. 1997 J. Pharmacol. Exp. Ther. pmid:9067323
Fisher JE et al. Trans-2-ene-valproic acid is less behaviorally teratogenic than an equivalent dose of valproic acid in rats. 1994 Teratology pmid:7747269
Kassahun K et al. Metabolic activation of unsaturated derivatives of valproic acid. Identification of novel glutathione adducts formed through coenzyme A-dependent and -independent processes. 1994 Chem. Biol. Interact. pmid:8168173
Lücke A et al. Diffusion analysis of valproate and trans-2-en-valproate in agar and in cerebral cortex of the rat. 1993 Brain Res. pmid:8131047