(2r, 3s)-2-hydroxybutane-1,2,3-tricarboxylate;2-hydroxybutane-1,2,3-tricarboxylate;2-methylcitrate

(2r, 3s)-2-hydroxybutane-1,2,3-tricarboxylate;2-hydroxybutane-1,2,3-tricarboxylate;2-methylcitrate is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 221 references associated with (2r, 3s)-2-hydroxybutane-1,2,3-tricarboxylate;2-hydroxybutane-1,2,3-tricarboxylate;2-methylcitrate in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for (2r, 3s)-2-hydroxybutane-1,2,3-tricarboxylate;2-hydroxybutane-1,2,3-tricarboxylate;2-methylcitrate

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (2r, 3s)-2-hydroxybutane-1,2,3-tricarboxylate;2-hydroxybutane-1,2,3-tricarboxylate;2-methylcitrate

MeSH term MeSH ID Detail
Vision Disorders D014786 10 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Pregnancy Complications D011248 19 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Total 5

PubChem Biomolecular Interactions and Pathways

All references with (2r, 3s)-2-hydroxybutane-1,2,3-tricarboxylate;2-hydroxybutane-1,2,3-tricarboxylate;2-methylcitrate

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Authors Title Published Journal PubMed Link
Peters H et al. A knock-out mouse model for methylmalonic aciduria resulting in neonatal lethality. 2003 J. Biol. Chem. pmid:14555645
Kölker S et al. Methylmalonic acid, a biochemical hallmark of methylmalonic acidurias but no inhibitor of mitochondrial respiratory chain. 2003 J. Biol. Chem. pmid:12972416
Grimek TL and Escalante-Semerena JC The acnD genes of Shewenella oneidensis and Vibrio cholerae encode a new Fe/S-dependent 2-methylcitrate dehydratase enzyme that requires prpF function in vivo. 2004 J. Bacteriol. pmid:14702315
Palacios S and Escalante-Semerena JC 2-Methylcitrate-dependent activation of the propionate catabolic operon (prpBCDE) of Salmonella enterica by the PrpR protein. 2004 Microbiology (Reading, Engl.) pmid:15528672
Lee SK and Keasling JD A propionate-inducible expression system for enteric bacteria. 2005 Appl. Environ. Microbiol. pmid:16269719
Campbell CD et al. Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency. 2005 Haematologica pmid:16464760
Ewering C et al. Metabolic engineering of strains of Ralstonia eutropha and Pseudomonas putida for biotechnological production of 2-methylcitric acid. 2006 Metab. Eng. pmid:16876450
Garvey GS et al. The three-dimensional crystal structure of the PrpF protein of Shewanella oneidensis complexed with trans-aconitate: insights into its biological function. 2007 Protein Sci. pmid:17567742
Plassmeier J et al. Investigation of central carbon metabolism and the 2-methylcitrate cycle in Corynebacterium glutamicum by metabolic profiling using gas chromatography-mass spectrometry. 2007 J. Biotechnol. pmid:17586079
Krawczyk H and Gradowska W 1H NMR spectra of methylcitric acid in urine. 2007 J. Inherit. Metab. Dis. pmid:17295121

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