2-acetolactate

2-acetolactate is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 253 references associated with 2-acetolactate in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-acetolactate

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-acetolactate

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-acetolactate

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Authors Title Published Journal PubMed Link
Belenky I et al. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I. 2012 FEBS J. pmid:22443469
Fuchs TM et al. Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection. 2012 Front Microbiol pmid:22347216
Lee S et al. Synthesis of pure meso-2,3-butanediol from crude glycerol using an engineered metabolic pathway in Escherichia coli. 2012 Appl. Biochem. Biotechnol. pmid:22434350
Kusunoki K and Ogata T Construction of self-cloning bottom-fermenting yeast with low vicinal diketone production by the homo-integration of ILV5. 2012 Yeast pmid:23038161
Lamsen EN and Atsumi S Recent progress in synthetic biology for microbial production of C3-C10 alcohols. 2012 Front Microbiol pmid:22701113
Hu W et al. Selective editing of Val and Leu methyl groups in high molecular weight protein NMR. 2012 J. Biomol. NMR pmid:22532128
van Leeuwen BN et al. Fermentative production of isobutene. 2012 Appl. Microbiol. Biotechnol. pmid:22234536
Hagel JM et al. Expressed sequence tag analysis of khat (Catha edulis) provides a putative molecular biochemical basis for the biosynthesis of phenylpropylamino alkaloids. 2011 Genet. Mol. Biol. pmid:22215969
Schröder J et al. Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation. 2011 BMC Genomics pmid:22053731
McLeod A et al. Global transcriptome response in Lactobacillus sakei during growth on ribose. 2011 BMC Microbiol. pmid:21702908
Pal RR et al. Genetic components of stringent response in Vibrio cholerae. 2011 Indian J. Med. Res. pmid:21415497
McDowell ET et al. Comparative functional genomic analysis of Solanum glandular trichome types. 2011 Plant Physiol. pmid:21098679
Green JM and Owen MD Herbicide-resistant crops: utilities and limitations for herbicide-resistant weed management. 2011 J. Agric. Food Chem. pmid:20586458
Amoêdo ND et al. Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. 2011 PLoS ONE pmid:21789245
Chen X et al. Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism. 2011 Biotechnol Biofuels pmid:21798060
Duong CT et al. Identification of Sc-type ILV6 as a target to reduce diacetyl formation in lager brewers' yeast. 2011 Metab. Eng. pmid:21824525
Smith KM et al. Engineering Corynebacterium glutamicum for isobutanol production. 2010 Appl. Microbiol. Biotechnol. pmid:20376637
Yu Q et al. AHAS herbicide resistance endowing mutations: effect on AHAS functionality and plant growth. 2010 J. Exp. Bot. pmid:20627897
Taghavi S et al. Genome sequence of the plant growth promoting endophytic bacterium Enterobacter sp. 638. 2010 PLoS Genet. pmid:20485560
Garg S et al. Thermodynamic analysis of regulation in metabolic networks using constraint-based modeling. 2010 BMC Res Notes pmid:20444261
Kissen R et al. Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. 2010 BMC Genomics pmid:20307264
Yamakawa H and Hakata M Atlas of rice grain filling-related metabolism under high temperature: joint analysis of metabolome and transcriptome demonstrated inhibition of starch accumulation and induction of amino acid accumulation. 2010 Plant Cell Physiol. pmid:20304786
McKinlay JB et al. A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. 2010 BMC Genomics pmid:21118570
Dellomonaco C et al. The path to next generation biofuels: successes and challenges in the era of synthetic biology. 2010 Microb. Cell Fact. pmid:20089184
Barve A et al. A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli. 2010 Adv Appl Bioinform Chem pmid:21918631
Follmann M et al. Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis. 2009 BMC Genomics pmid:20025733
Bertalan M et al. Complete genome sequence of the sugarcane nitrogen-fixing endophyte Gluconacetobacter diazotrophicus Pal5. 2009 BMC Genomics pmid:19775431
Audic S et al. Brucella microti: the genome sequence of an emerging pathogen. 2009 BMC Genomics pmid:19653890
Wang JG et al. Crystal structures of two novel sulfonylurea herbicides in complex with Arabidopsis thaliana acetohydroxyacid synthase. 2009 FEBS J. pmid:19187232
Kenny JG et al. The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications. 2009 PLoS ONE pmid:19183815
Knill T et al. Arabidopsis thaliana encodes a bacterial-type heterodimeric isopropylmalate isomerase involved in both Leu biosynthesis and the Met chain elongation pathway of glucosinolate formation. 2009 Plant Mol. Biol. pmid:19597944
Kouskoumvekaki I et al. Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification. 2008 BMC Bioinformatics pmid:18226195
Tsang LH et al. Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants. 2008 PLoS ONE pmid:18846215
Barriuso-Iglesias M et al. Response of the cytoplasmic and membrane proteome of Corynebacterium glutamicum ATCC 13032 to pH changes. 2008 BMC Microbiol. pmid:19091079
Saw JH et al. Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1. 2008 Genome Biol. pmid:19014707
Moreno-Sánchez R et al. Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways. 2008 J. Biomed. Biotechnol. pmid:18629230
Le Bars D and Yvon M Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism. 2008 J. Appl. Microbiol. pmid:17850313
Chen LS et al. Harnessing naturally randomized transcription to infer regulatory relationships among genes. 2007 Genome Biol. pmid:17931418
Jamshidi N and Palsson BØ Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets. 2007 BMC Syst Biol pmid:17555602
Tsantili IC et al. Quantifying the metabolic capabilities of engineered Zymomonas mobilis using linear programming analysis. 2007 Microb. Cell Fact. pmid:17349037
Baykal A et al. Synthesis with good enantiomeric excess of both enantiomers of alpha-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases. 2006 Bioorg. Chem. pmid:17083961
Kulp DC and Jagalur M Causal inference of regulator-target pairs by gene mapping of expression phenotypes. 2006 BMC Genomics pmid:16719927
Oliveira AP et al. Modeling Lactococcus lactis using a genome-scale flux model. 2005 BMC Microbiol. pmid:15982422
Kobayashi K et al. Method for the simultaneous assay of diacetyl and acetoin in the presence of alpha-acetolactate: application in determining the kinetic parameters for the decomposition of alpha-acetolactate. 2005 J. Biosci. Bioeng. pmid:16233823
Nemeria N et al. Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity. 2005 J. Biol. Chem. pmid:15802265
Pang SS et al. The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate. 2004 J. Biol. Chem. pmid:14557277
Engel S et al. Role of a conserved arginine in the mechanism of acetohydroxyacid synthase: catalysis of condensation with a specific ketoacid substrate. 2004 J. Biol. Chem. pmid:15044456
Monnet C et al. Regulation of branched-chain amino acid biosynthesis by alpha-acetolactate decarboxylase in Streptococcus thermophilus. 2003 Lett. Appl. Microbiol. pmid:12753249
O'Sullivan SM et al. Purification and characterisation of acetolactate decarboxylase from Leuconostoc lactis NCW1. 2001 FEMS Microbiol. Lett. pmid:11164316
Sergienko EA and Jordan F Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products. 2001 Biochemistry pmid:11412091
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