2-hydroxyglutaric acid

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Canavan Disease D017825 2 associated lipids
Tyrosinemias D020176 2 associated lipids
Hyperoxaluria D006959 3 associated lipids
Phenylketonurias D010661 7 associated lipids
Metabolic Diseases D008659 12 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Tomlinson L et al. Cannabinoid receptor antagonist-induced striated muscle toxicity and ethylmalonic-adipic aciduria in beagle dogs. 2012 Toxicol. Sci. pmid:22821849
Chang YJ et al. Complete genome sequence of Acidaminococcus fermentans type strain (VR4). 2010 Stand Genomic Sci pmid:21304687
Chovatia M et al. Complete genome sequence of Thermanaerovibrio acidaminovorans type strain (Su883). 2009 Stand Genomic Sci pmid:21304665
Wang F et al. Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. 2013 Science pmid:23558173
Rohle D et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. 2013 Science pmid:23558169
Losman JA et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. 2013 Science pmid:23393090
Kranendijk M et al. IDH2 mutations in patients with D-2-hydroxyglutaric aciduria. 2010 Science pmid:20847235
Elkhaled A et al. Magnetic resonance of 2-hydroxyglutarate in IDH1-mutated low-grade gliomas. 2012 Sci Transl Med pmid:22238333
Andronesi OC et al. Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy. 2012 Sci Transl Med pmid:22238332
Cheng QY et al. Sensitive Determination of Onco-metabolites of D- and L-2-hydroxyglutarate Enantiomers by Chiral Derivatization Combined with Liquid Chromatography/Mass Spectrometry Analysis. 2015 Sci Rep pmid:26458332