2-hydroxyglutaric acid

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Canavan Disease D017825 2 associated lipids
Tyrosinemias D020176 2 associated lipids
Hyperoxaluria D006959 3 associated lipids
Phenylketonurias D010661 7 associated lipids
Metabolic Diseases D008659 12 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Li L et al. Treatment with a Small Molecule Mutant IDH1 Inhibitor Suppresses Tumorigenic Activity and Decreases Production of the Oncometabolite 2-Hydroxyglutarate in Human Chondrosarcoma Cells. 2015 PLoS ONE pmid:26368816
Rzem R et al. A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair. 2015 PLoS ONE pmid:25763823
Saccenti E et al. Simplivariate models: uncovering the underlying biology in functional genomics data. 2011 PLoS ONE pmid:21698241
Fong MY et al. Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer. 2011 PLoS ONE pmid:21625518
Ohka F et al. The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma. 2011 PLoS ONE pmid:21829728
Lages E et al. MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. 2011 PLoS ONE pmid:21655185
Krell D et al. Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. 2011 PLoS ONE pmid:21625441
Jin G et al. 2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations. 2011 PLoS ONE pmid:21326614
Hageman JA et al. Simplivariate models: ideas and first examples. 2008 PLoS ONE pmid:18810272
Rönicke R et al. Abeta mediated diminution of MTT reduction--an artefact of single cell culture? 2008 PLoS ONE pmid:18800168