2-hydroxyglutaric acid

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Metabolic Diseases D008659 12 associated lipids
Phenylketonurias D010661 7 associated lipids
Hyperoxaluria D006959 3 associated lipids
Canavan Disease D017825 2 associated lipids
Tyrosinemias D020176 2 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Durán RV and Hall MN Glutaminolysis feeds mTORC1. 2012 Cell Cycle pmid:23095634
Lazovic J et al. Detection of 2-hydroxyglutaric acid in vivo by proton magnetic resonance spectroscopy in U87 glioma cells overexpressing isocitrate dehydrogenase-1 mutation. 2012 Neuro-oncology pmid:23090985
Fathi AT et al. Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response. 2012 Blood pmid:23074281
Yang H et al. IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives. 2012 Clin. Cancer Res. pmid:23071358
Sasaki M et al. D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. 2012 Genes Dev. pmid:22925884
Yang M et al. The emerging role of fumarate as an oncometabolite. 2012 Front Oncol pmid:22866264
Li Y et al. Combined inactivation of the Clostridium cellulolyticum lactate and malate dehydrogenase genes substantially increases ethanol yield from cellulose and switchgrass fermentations. 2012 Biotechnol Biofuels pmid:22214220
Borger DR et al. Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping. 2012 Oncologist pmid:22180306
Luchman HA et al. An in vivo patient-derived model of endogenous IDH1-mutant glioma. 2012 Neuro-oncology pmid:22166263
Borodovsky A et al. Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2. 2012 Curr Opin Oncol pmid:22080945