2-hydroxyglutaric acid

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Metabolic Diseases D008659 12 associated lipids
Phenylketonurias D010661 7 associated lipids
Hyperoxaluria D006959 3 associated lipids
Canavan Disease D017825 2 associated lipids
Tyrosinemias D020176 2 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Tai H and Zhang Z A novel compound heterozygous mutation in a Chinese boy with L-2-hydroxyglutaric aciduria: a case study. 2015 BMC Neurol pmid:26208971
Fu X et al. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. 2015 Cell Metab. pmid:26190651
Hwang VJ et al. The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. 2015 Am. J. Physiol. Renal Physiol. pmid:26155843
Macaulay RJ Impending Impact of Molecular Pathology on Classifying Adult Diffuse Gliomas. 2015 Cancer Control pmid:26068765
Suijker J et al. The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo. 2015 Oncotarget pmid:26046462
Izquierdo-Garcia JL et al. IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism. 2015 Cancer Res. pmid:26045167
Pichumani K et al. Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas. 2015 Anal. Biochem. pmid:25908561
Lombardi G et al. Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma. 2015 Oncologist pmid:25862748
Pellegatta S et al. Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma. 2015 Acta Neuropathol Commun pmid:25849072
Ma S et al. D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. 2015 Oncotarget pmid:25825982