2-hydroxyglutaric acid

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Metabolic Diseases D008659 12 associated lipids
Phenylketonurias D010661 7 associated lipids
Hyperoxaluria D006959 3 associated lipids
Tyrosinemias D020176 2 associated lipids
Canavan Disease D017825 2 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Roymoulik I et al. Rearrangement of L-2-hydroxyglutarate to L-threo-3-methylmalate catalyzed by adenosylcobalamin-dependent glutamate mutase. 2000 Biochemistry pmid:10956023
van der Knaap MS et al. D-2-Hydroxyglutaric aciduria: biochemical marker or clinical disease entity? 1999 Ann. Neurol. pmid:9894884
Zhao G and Winkler ME A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria. 1996 J. Bacteriol. pmid:8550422
Verhaeghe BJ et al. Solid-phase extraction with strong anion-exchange columns for selective isolation and concentration of urinary organic acids. 1988 Clin. Chem. pmid:3378323
Kaufman EE et al. Isolation and characterization of a hydroxyacid-oxoacid transhydrogenase from rat kidney mitochondria. 1988 J. Biol. Chem. pmid:3182820
Fernández-Briera A and Garrido-Pertierra A A degradation pathway of propionate in Salmonella typhimurium LT-2. 1988 Biochimie pmid:2844305
Kuhara T et al. Studies of urinary organic acid profiles of a patient with dihydrolipoyl dehydrogenase deficiency. 1983 Clin. Chim. Acta pmid:6688766
Buckel W The reversible dehydration of (R)-2-hydroxyglutarate to (E)-glutaconate. 1980 Eur. J. Biochem. pmid:7398622
REEVES HC et al. ALPHA-HYDROXYGLUTARATE: PRODUCT OF AN ENZYMATIC BETA-CONDENSATION BETWEEN GLYOXYLATE AND PROPIONYL-COENZYME A. 1963 J. Bacteriol. pmid:14086118
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