2-hydroxyglutaric acid

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Metabolic Diseases D008659 12 associated lipids
Phenylketonurias D010661 7 associated lipids
Hyperoxaluria D006959 3 associated lipids
Canavan Disease D017825 2 associated lipids
Tyrosinemias D020176 2 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Chotirat S et al. Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. 2012 J Hematol Oncol pmid:22397365
Kranendijk M et al. Progress in understanding 2-hydroxyglutaric acidurias. 2012 J. Inherit. Metab. Dis. pmid:22391998
Constantin A et al. Identifying malignant transformations in recurrent low grade gliomas using high resolution magic angle spinning spectroscopy. 2012 Artif Intell Med pmid:22387185
Tefferi A et al. IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F. 2012 Leukemia pmid:21912393
Lecoeur H et al. HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase. 2012 Cell Death Dis pmid:22419111
Saccenti E et al. Simplivariate models: uncovering the underlying biology in functional genomics data. 2011 PLoS ONE pmid:21698241
Fong MY et al. Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer. 2011 PLoS ONE pmid:21625518
Bhatia S et al. Mycosporine and mycosporine-like amino acids: A paramount tool against ultra violet irradiation. 2011 Pharmacogn Rev pmid:22279371
D'Alò F et al. Similarities and differences between therapy-related and elderly acute myeloid leukemia. 2011 Mediterr J Hematol Infect Dis pmid:22220249
Ohka F et al. The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma. 2011 PLoS ONE pmid:21829728
Marie SK and Shinjo SM Metabolism and brain cancer. 2011 Clinics (Sao Paulo) pmid:21779721
Araújo WL et al. Analysis of a range of catabolic mutants provides evidence that phytanoyl-coenzyme A does not act as a substrate of the electron-transfer flavoprotein/electron-transfer flavoprotein:ubiquinone oxidoreductase complex in Arabidopsis during dark-induced senescence. 2011 Plant Physiol. pmid:21788362
Scott JG et al. Production of 2-hydroxyglutarate by isocitrate dehydrogenase 1-mutated gliomas: an evolutionary alternative to the Warburg shift? 2011 Neuro-oncology pmid:21784755
Bralten LB et al. Absence of common somatic alterations in genes on 1p and 19q in oligodendrogliomas. 2011 PLoS ONE pmid:21760942
Lages E et al. MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. 2011 PLoS ONE pmid:21655185
Passamonti F et al. Myeloproliferative neoplasms: from JAK2 mutations discovery to JAK2 inhibitor therapies. 2011 Oncotarget pmid:21646683
Krell D et al. Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. 2011 PLoS ONE pmid:21625441
Yan W et al. Oncogene addiction in gliomas: implications for molecular targeted therapy. 2011 J. Exp. Clin. Cancer Res. pmid:21575270
Ramezani M et al. Glutamate racemization and catabolism in Fusobacterium varium. 2011 FEBS J. pmid:21575137
O'Keefe LV et al. Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. 2011 Hum. Mol. Genet. pmid:21075834