Kingsbury JM et al. |
Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability. |
2016 |
Hum. Mol. Genet. |
pmid:27427385
|
Jafari-Khouzani K et al. |
Volumetric relationship between 2-hydroxyglutarate and FLAIR hyperintensity has potential implications for radiotherapy planning of mutant IDH glioma patients. |
2016 |
Neuro-oncology |
pmid:27382115
|
Fujii T et al. |
Targeting isocitrate dehydrogenase (IDH) in cancer. |
2016 |
Discov Med |
pmid:27355333
|
Ricoult SJ et al. |
Sterol Regulatory Element Binding Protein Regulates the Expression and Metabolic Functions of Wild-Type and Oncogenic IDH1. |
2016 |
Mol. Cell. Biol. |
pmid:27354064
|
Teng X et al. |
Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis. |
2016 |
ACS Chem. Biol. |
pmid:27333189
|
Nagashima H et al. |
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma. |
2016 |
Neuro-oncology |
pmid:27154922
|
Chaturvedi A et al. |
Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate. |
2016 |
Leukemia |
pmid:27063596
|
Fiehn O et al. |
Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. |
2016 |
Elife |
pmid:26943899
|
Fathi AT et al. |
Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma. |
2016 |
Oncologist |
pmid:26834160
|
Heo H et al. |
On the Utility of Short Echo Time (TE) Single Voxel 1H-MRS in Non-Invasive Detection of 2-Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel. |
2016 |
PLoS ONE |
pmid:26820720
|
Becker-Kettern J et al. |
Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase. |
2016 |
J. Biol. Chem. |
pmid:26774271
|
Flavahan WA et al. |
Insulator dysfunction and oncogene activation in IDH mutant gliomas. |
2016 |
Nature |
pmid:26700815
|
Waitkus MS et al. |
Isocitrate dehydrogenase mutations in gliomas. |
2016 |
Neuro-oncology |
pmid:26188014
|
Wang P et al. |
Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. |
2015 |
Cell Rep |
pmid:26686626
|
Tateishi K et al. |
Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion. |
2015 |
Cancer Cell |
pmid:26678339
|
Pichumani K et al. |
Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas. |
2015 |
Anal. Biochem. |
pmid:25908561
|
Lombardi G et al. |
Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma. |
2015 |
Oncologist |
pmid:25862748
|
Pellegatta S et al. |
Effective immuno-targeting of the IDH1 mutation R132H in a murine model of intracranial glioma. |
2015 |
Acta Neuropathol Commun |
pmid:25849072
|
Ma S et al. |
D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. |
2015 |
Oncotarget |
pmid:25825982
|
Oizel K et al. |
D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH. |
2015 |
Cell Death Dis |
pmid:25811801
|