2-hydroxyglutaric acid

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Phenylketonurias D010661 7 associated lipids
Canavan Disease D017825 2 associated lipids
Metabolic Diseases D008659 12 associated lipids
Tyrosinemias D020176 2 associated lipids
Hyperoxaluria D006959 3 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
pmid:15824270
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Struys EA et al. Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma-hydroxybutyric acidurias. 2005 J. Inherit. Metab. Dis. pmid:16435184
Read MH et al. Clinical, biochemical, magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) findings in a fourth case of combined D- and L-2 hydroxyglutaric aciduria. 2005 J. Inherit. Metab. Dis. pmid:16435212
Struys EA et al. D-2-hydroxyglutaric aciduria in three patients with proven SSADH deficiency: genetic coincidence or a related biochemical epiphenomenon? 2006 Mol. Genet. Metab. pmid:16442322
pmid:16460720
Heux S et al. Cofactor engineering in Saccharomyces cerevisiae: Expression of a H2O-forming NADH oxidase and impact on redox metabolism. 2006 Metab. Eng. pmid:16473032
pmid:16483879
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Boiangiu CD et al. Sodium ion pumps and hydrogen production in glutamate fermenting anaerobic bacteria. 2005 J. Mol. Microbiol. Biotechnol. pmid:16645308
pmid:16722976
pmid:16769228
pmid:16802109
pmid:16814516
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Pearson LA et al. Characterization of the 2-hydroxy-acid dehydrogenase McyI, encoded within the microcystin biosynthesis gene cluster of Microcystis aeruginosa PCC7806. 2007 J. Biol. Chem. pmid:17142460
pmid:17249667
Penderis J et al. L-2-hydroxyglutaric aciduria: characterisation of the molecular defect in a spontaneous canine model. 2007 J. Med. Genet. pmid:17475916
pmid:17537659
Butler JE et al. Genomic and microarray analysis of aromatics degradation in Geobacter metallireducens and comparison to a Geobacter isolate from a contaminated field site. 2007 BMC Genomics pmid:17578578
pmid:17603759
pmid:17876720
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pmid:17917788
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Bal D et al. Investigation of a wide spectrum of inherited metabolic disorders by 13C NMR spectroscopy. 2008 Acta Biochim. Pol. pmid:18217108
Hans M et al. Spectroscopic evidence for an all-ferrous [4Fe-4S]0 cluster in the superreduced activator of 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans. 2008 J. Biol. Inorg. Chem. pmid:18274792
pmid:18295785
pmid:18343698
Hagos Y et al. Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias. 2008 Pflugers Arch. pmid:18365245
Kalliri E et al. Identification of Escherichia coli YgaF as an L-2-hydroxyglutarate oxidase. 2008 J. Bacteriol. pmid:18390652
pmid:18404412
Kahmen A et al. Foliar delta(15)N values characterize soil N cycling and reflect nitrate or ammonium preference of plants along a temperate grassland gradient. 2008 Oecologia pmid:18414899
pmid:18415700
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pmid:18671189
Rönicke R et al. Abeta mediated diminution of MTT reduction--an artefact of single cell culture? 2008 PLoS ONE pmid:18800168
Hageman JA et al. Simplivariate models: ideas and first examples. 2008 PLoS ONE pmid:18810272
pmid:18931888
pmid:19005678