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Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma. |
2016 |
Neuro-oncology |
pmid:27154922
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Chaturvedi A et al. |
Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate. |
2016 |
Leukemia |
pmid:27063596
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Fiehn O et al. |
Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. |
2016 |
Elife |
pmid:26943899
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Wang P et al. |
Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents. |
2015 |
Cell Rep |
pmid:26686626
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Oizel K et al. |
D-2-Hydroxyglutarate does not mimic all the IDH mutation effects, in particular the reduced etoposide-triggered apoptosis mediated by an alteration in mitochondrial NADH. |
2015 |
Cell Death Dis |
pmid:25811801
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Keum YS and Choi BY |
Isocitrate dehydrogenase mutations: new opportunities for translational research. |
2015 |
BMB Rep |
pmid:25787993
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Shi X et al. |
Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish. |
2015 |
Blood |
pmid:25778530
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Rzem R et al. |
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair. |
2015 |
PLoS ONE |
pmid:25763823
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Hirata M et al. |
Mutant IDH is sufficient to initiate enchondromatosis in mice. |
2015 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:25730874
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Charitou P et al. |
FOXOs support the metabolic requirements of normal and tumor cells by promoting IDH1 expression. |
2015 |
EMBO Rep. |
pmid:25648147
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