(2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin

Introduction

To understand associated biological information of (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Glucose Intolerance D018149 13 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin?

There are no associated biomedical information in the current reference collection.

What functions are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin

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Authors Title Published Journal PubMed Link
Kodedová M and Sychrová H Synthetic antimicrobial peptides of the halictines family disturb the membrane integrity of Candida cells. 2017 Biochim. Biophys. Acta pmid:28600071
Blachnio-Zabielska AU et al. The Crucial Role of C18-Cer in Fat-Induced Skeletal Muscle Insulin Resistance. 2016 Cell. Physiol. Biochem. pmid:27960149
Aburasayn H et al. Targeting ceramide metabolism in obesity. 2016 Am. J. Physiol. Endocrinol. Metab. pmid:27382035
García-Marqués S et al. Sng1 associates with Nce102 to regulate the yeast Pkh-Ypk signalling module in response to sphingolipid status. 2016 Biochim. Biophys. Acta pmid:27033517
Stefanovic M et al. Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma. 2016 Oncotarget pmid:26811497
Mallela SK et al. Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae. 2016 PLoS ONE pmid:26752183
Chauhan N et al. Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1. 2016 J. Biol. Chem. pmid:26634277
Salaun E et al. Myriocin prevents muscle ceramide accumulation but not muscle fiber atrophy during short-term mechanical unloading. 2016 J. Appl. Physiol. pmid:26542521
Lindahl L et al. Sphingolipids contribute to acetic acid resistance in Zygosaccharomyces bailii. 2016 Biotechnol. Bioeng. pmid:26416641
Yin S et al. Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells. 2016 Arch. Toxicol. pmid:25925693
Babenko NA and Kharchenko VS Effects of inhibitors of key enzymes of sphingolipid metabolism on insulin-induced glucose uptake and glycogen synthesis in liver cells of old rats. 2015 Biochemistry Mosc. pmid:25754045
Cozza G et al. A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins. 2015 Biochim. Biophys. Acta pmid:25936777
Wang J et al. Fungal metabolite myriocin promotes human herpes simplex virus-2 infection. 2015 Life Sci. pmid:25447452
Martínez L et al. Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. 2015 Oncotarget pmid:26539645
Hodson AE et al. Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function. 2015 Cardiovasc Diabetol pmid:26682540
Perdoni F et al. Antifungal activity of Myriocin on clinically relevant Aspergillus fumigatus strains producing biofilm. 2015 BMC Microbiol. pmid:26519193
Athanasopoulos A et al. Characterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis. 2015 Sci Rep pmid:26468899
Jun BK et al. Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia. 2015 J. Neurosci. pmid:26446223
Kurek K et al. Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance. 2015 J Diabetes Res pmid:26380311
Bharath LP et al. Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo. 2015 Diabetes pmid:26253611
Aktepe TE et al. Differential utilisation of ceramide during replication of the flaviviruses West Nile and dengue virus. 2015 Virology pmid:26122470
Kasumov T et al. Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. 2015 PLoS ONE pmid:25993337
Nelson MB et al. Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-product signaling in a ceramide-dependent manner. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:25957215
Gupta SD et al. Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells. 2015 J. Biol. Chem. pmid:25395622
Samokhvalov V et al. PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. 2015 Toxicol. Lett. pmid:25300478
Hamada Y et al. Involvement of de novo ceramide synthesis in pro-inflammatory adipokine secretion and adipocyte-macrophage interaction. 2014 J. Nutr. Biochem. pmid:25283329
Chow SE et al. Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells. 2014 Apoptosis pmid:24264887
Swinnen E et al. The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. 2014 Mol. Biol. Cell pmid:24196832
Tippetts TS et al. Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. 2014 BMC Cardiovasc Disord pmid:25416336
Raichur S et al. CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. 2014 Cell Metab. pmid:25295789
Thatcher MO et al. Ceramides mediate cigarette smoke-induced metabolic disruption in mice. 2014 Am. J. Physiol. Endocrinol. Metab. pmid:25269485
Surlow BA et al. Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation. 2014 J. Biol. Chem. pmid:25258318
Li W et al. Endogenous ceramide contributes to the transcytosis of oxLDL across endothelial cells and promotes its subendothelial retention in vascular wall. 2014 Oxid Med Cell Longev pmid:24817993
Correnti JM et al. Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice. 2014 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:24742988
Kurek K et al. Inhibition of ceramide de novo synthesis with myriocin affects lipid metabolism in the liver of rats with streptozotocin-induced type 1 diabetes. 2014 Biomed Res Int pmid:24701589
Curto MÁ et al. Membrane organization and cell fusion during mating in fission yeast requires multipass membrane protein Prm1. 2014 Genetics pmid:24514900
Yamane-Sando Y et al. Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion. 2014 Microbiologyopen pmid:24510621
Tong M et al. Therapeutic reversal of chronic alcohol-related steatohepatitis with the ceramide inhibitor myriocin. 2014 Int J Exp Pathol pmid:24456332
Caretti A et al. Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis. 2014 Biochim. Biophys. Acta pmid:24141140
Kasumov T et al. 2H2O-based high-density lipoprotein turnover method for the assessment of dynamic high-density lipoprotein function in mice. 2013 Arterioscler. Thromb. Vasc. Biol. pmid:23766259
Meszaros P et al. Long term myriocin treatment increases MRP1 transport activity. 2013 Int. J. Biochem. Cell Biol. pmid:23178537
Zhang O et al. Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence. 2013 Mol. Microbiol. pmid:23980754
Mikłosz A et al. Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubes. 2013 PLoS ONE pmid:24376889
de Melo NR et al. Myriocin significantly increases the mortality of a non-mammalian model host during Candida pathogenesis. 2013 PLoS ONE pmid:24260135
Lizarazo D et al. Ceramide inhibitor myriocin restores insulin/insulin growth factor signaling for liver remodeling in experimental alcohol-related steatohepatitis. 2013 J. Gastroenterol. Hepatol. pmid:23802886
Liu J et al. Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan. 2013 Aging Cell pmid:23725375
Worgall TS et al. Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity. 2013 Sci Transl Med pmid:23698380
Huang X et al. Reducing signs of aging and increasing lifespan by drug synergy. 2013 Aging Cell pmid:23601176
Tafesse FG et al. Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:23576732
Dekker MJ et al. Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. 2013 Atherosclerosis pmid:23466071