MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Glucose Intolerance | D018149 | 13 associated lipids |
To understand associated biological information of (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with (2s,3r,4r,6e)-2-amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid;isp-i;thermozymocidin
MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Glucose Intolerance | D018149 | 13 associated lipids |
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Kodedová M and Sychrová H | Synthetic antimicrobial peptides of the halictines family disturb the membrane integrity of Candida cells. | 2017 | Biochim. Biophys. Acta | pmid:28600071 |
Blachnio-Zabielska AU et al. | The Crucial Role of C18-Cer in Fat-Induced Skeletal Muscle Insulin Resistance. | 2016 | Cell. Physiol. Biochem. | pmid:27960149 |
Aburasayn H et al. | Targeting ceramide metabolism in obesity. | 2016 | Am. J. Physiol. Endocrinol. Metab. | pmid:27382035 |
GarcÃa-Marqués S et al. | Sng1 associates with Nce102 to regulate the yeast Pkh-Ypk signalling module in response to sphingolipid status. | 2016 | Biochim. Biophys. Acta | pmid:27033517 |
Stefanovic M et al. | Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma. | 2016 | Oncotarget | pmid:26811497 |
Mallela SK et al. | Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae. | 2016 | PLoS ONE | pmid:26752183 |
Chauhan N et al. | Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1. | 2016 | J. Biol. Chem. | pmid:26634277 |
Salaun E et al. | Myriocin prevents muscle ceramide accumulation but not muscle fiber atrophy during short-term mechanical unloading. | 2016 | J. Appl. Physiol. | pmid:26542521 |
Lindahl L et al. | Sphingolipids contribute to acetic acid resistance in Zygosaccharomyces bailii. | 2016 | Biotechnol. Bioeng. | pmid:26416641 |
Yin S et al. | Fumonisin B1 induces autophagic cell death via activation of ERN1-MAPK8/9/10 pathway in monkey kidney MARC-145 cells. | 2016 | Arch. Toxicol. | pmid:25925693 |
Babenko NA and Kharchenko VS | Effects of inhibitors of key enzymes of sphingolipid metabolism on insulin-induced glucose uptake and glycogen synthesis in liver cells of old rats. | 2015 | Biochemistry Mosc. | pmid:25754045 |
Cozza G et al. | A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins. | 2015 | Biochim. Biophys. Acta | pmid:25936777 |
Wang J et al. | Fungal metabolite myriocin promotes human herpes simplex virus-2 infection. | 2015 | Life Sci. | pmid:25447452 |
MartÃnez L et al. | Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. | 2015 | Oncotarget | pmid:26539645 |
Hodson AE et al. | Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function. | 2015 | Cardiovasc Diabetol | pmid:26682540 |
Perdoni F et al. | Antifungal activity of Myriocin on clinically relevant Aspergillus fumigatus strains producing biofilm. | 2015 | BMC Microbiol. | pmid:26519193 |
Athanasopoulos A et al. | Characterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis. | 2015 | Sci Rep | pmid:26468899 |
Jun BK et al. | Substrate Availability of Mutant SPT Alters Neuronal Branching and Growth Cone Dynamics in Dorsal Root Ganglia. | 2015 | J. Neurosci. | pmid:26446223 |
Kurek K et al. | Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance. | 2015 | J Diabetes Res | pmid:26380311 |
Bharath LP et al. | Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo. | 2015 | Diabetes | pmid:26253611 |
Aktepe TE et al. | Differential utilisation of ceramide during replication of the flaviviruses West Nile and dengue virus. | 2015 | Virology | pmid:26122470 |
Kasumov T et al. | Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. | 2015 | PLoS ONE | pmid:25993337 |
Nelson MB et al. | Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-product signaling in a ceramide-dependent manner. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:25957215 |
Gupta SD et al. | Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells. | 2015 | J. Biol. Chem. | pmid:25395622 |
Samokhvalov V et al. | PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. | 2015 | Toxicol. Lett. | pmid:25300478 |
Hamada Y et al. | Involvement of de novo ceramide synthesis in pro-inflammatory adipokine secretion and adipocyte-macrophage interaction. | 2014 | J. Nutr. Biochem. | pmid:25283329 |
Chow SE et al. | Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells. | 2014 | Apoptosis | pmid:24264887 |
Swinnen E et al. | The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. | 2014 | Mol. Biol. Cell | pmid:24196832 |
Tippetts TS et al. | Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. | 2014 | BMC Cardiovasc Disord | pmid:25416336 |
Raichur S et al. | CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. | 2014 | Cell Metab. | pmid:25295789 |
Thatcher MO et al. | Ceramides mediate cigarette smoke-induced metabolic disruption in mice. | 2014 | Am. J. Physiol. Endocrinol. Metab. | pmid:25269485 |
Surlow BA et al. | Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation. | 2014 | J. Biol. Chem. | pmid:25258318 |
Li W et al. | Endogenous ceramide contributes to the transcytosis of oxLDL across endothelial cells and promotes its subendothelial retention in vascular wall. | 2014 | Oxid Med Cell Longev | pmid:24817993 |
Correnti JM et al. | Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:24742988 |
Kurek K et al. | Inhibition of ceramide de novo synthesis with myriocin affects lipid metabolism in the liver of rats with streptozotocin-induced type 1 diabetes. | 2014 | Biomed Res Int | pmid:24701589 |
Curto MÃ et al. | Membrane organization and cell fusion during mating in fission yeast requires multipass membrane protein Prm1. | 2014 | Genetics | pmid:24514900 |
Yamane-Sando Y et al. | Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion. | 2014 | Microbiologyopen | pmid:24510621 |
Tong M et al. | Therapeutic reversal of chronic alcohol-related steatohepatitis with the ceramide inhibitor myriocin. | 2014 | Int J Exp Pathol | pmid:24456332 |
Caretti A et al. | Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis. | 2014 | Biochim. Biophys. Acta | pmid:24141140 |
Kasumov T et al. | 2H2O-based high-density lipoprotein turnover method for the assessment of dynamic high-density lipoprotein function in mice. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23766259 |
Meszaros P et al. | Long term myriocin treatment increases MRP1 transport activity. | 2013 | Int. J. Biochem. Cell Biol. | pmid:23178537 |
Zhang O et al. | Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence. | 2013 | Mol. Microbiol. | pmid:23980754 |
Mikłosz A et al. | Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubes. | 2013 | PLoS ONE | pmid:24376889 |
de Melo NR et al. | Myriocin significantly increases the mortality of a non-mammalian model host during Candida pathogenesis. | 2013 | PLoS ONE | pmid:24260135 |
Lizarazo D et al. | Ceramide inhibitor myriocin restores insulin/insulin growth factor signaling for liver remodeling in experimental alcohol-related steatohepatitis. | 2013 | J. Gastroenterol. Hepatol. | pmid:23802886 |
Liu J et al. | Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan. | 2013 | Aging Cell | pmid:23725375 |
Worgall TS et al. | Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity. | 2013 | Sci Transl Med | pmid:23698380 |
Huang X et al. | Reducing signs of aging and increasing lifespan by drug synergy. | 2013 | Aging Cell | pmid:23601176 |
Tafesse FG et al. | Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23576732 |
Dekker MJ et al. | Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. | 2013 | Atherosclerosis | pmid:23466071 |