Haneda Y et al. |
Leukotriene D4 enhances tumor necrosis factor-α-induced vascular endothelial growth factor production in human monocytes/macrophages. |
2011 |
Cytokine |
pmid:21482134
|
Spector SL |
Leukotriene activity modulation in asthma. |
1997 |
Drugs |
pmid:9279501
|
Ciana P et al. |
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. |
2006 |
EMBO J. |
pmid:16990797
|
Traianedes K et al. |
5-Lipoxygenase metabolites inhibit bone formation in vitro. |
1998 |
Endocrinology |
pmid:9645691
|
Hazel BA et al. |
Induction of granulocytic differentiation in a mouse model by benzene and hydroquinone. |
1996 |
Environ. Health Perspect. |
pmid:9118902
|
Ballart B et al. |
Synthesis and pharmacological evaluation of new 4-2-(7-heterocyclemethoxynaftalen-2-ylmethoxy)ethylbenzoic acids as LTD(4)-antagonists. |
2000 |
Eur J Med Chem |
pmid:10858604
|
Thioudellet C et al. |
Molecular and functional characterization of recombinant human gamma-glutamyltransferase. Coupling of its activity to glutathione levels in V79 cells. |
1994 |
Eur. J. Biochem. |
pmid:7913033
|
Lankisch TO et al. |
High-affinity cholecystokinin type A receptor/cytosolic phospholipase A2 pathways mediate Ca2+ oscillations via a positive feedback regulation by calmodulin kinase in pancreatic acini. |
1999 |
Eur. J. Cell Biol. |
pmid:10535305
|
Massoumi R and Sjölander A |
The inflammatory mediator leukotriene D4 triggers a rapid reorganisation of the actin cytoskeleton in human intestinal epithelial cells. |
1998 |
Eur. J. Cell Biol. |
pmid:9716265
|
Ibe BO et al. |
Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. |
1994 |
Eur. J. Clin. Invest. |
pmid:8187808
|
Dahlén B et al. |
Salbutamol but not ipratropium abolishes leukotriene D4-induced gas exchange abnormalities in asthma. |
2012 |
Eur. J. Clin. Pharmacol. |
pmid:22457014
|
Przylipiak A et al. |
Influence of leukotrienes on in vitro growth of human mammary carcinoma cell line MCF-7. |
1998 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:9550202
|
Sugahara S et al. |
Kinins are involved in the development of allergic nasal hyperresponsiveness in guinea pigs. |
2003 |
Eur. J. Pharmacol. |
pmid:12969770
|
Rehn M and Diener M |
Cysteinyl leukotrienes mediate the response of submucosal ganglia from rat colon to bradykinin. |
2012 |
Eur. J. Pharmacol. |
pmid:22366210
|
Yoshikawa S et al. |
Modulation of acetylcholine release from the myenteric plexus of guinea-pig ileum by 5-lipoxygenase metabolites of arachidonic acid. |
1993 |
Eur. J. Pharmacol. |
pmid:8223906
|
Tudhope SR et al. |
BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. |
1994 |
Eur. J. Pharmacol. |
pmid:7698171
|
Bäck M et al. |
The cysteinyl-leukotriene receptor antagonist BAY u9773 is a competitive antagonist of leukotriene C4 in the guinea-pig ileum. |
1996 |
Eur. J. Pharmacol. |
pmid:8982726
|
Ohbayashi H et al. |
Compared effects of natriuretic peptides on ovalbumin-induced asthmatic model. |
1998 |
Eur. J. Pharmacol. |
pmid:9617752
|
Rehni AK et al. |
Pharmacological modulation of leukotriene D(4) attenuates the development of opioid dependence in a mouse model of naloxone-induced opioid withdrawal syndrome. |
2008 |
Eur. J. Pharmacol. |
pmid:18840427
|
Mizutani N et al. |
Effect of TA-270, a novel quinolinone derivative, on antigen-induced nasal blockage in a guinea pig model of allergic rhinitis. |
2009 |
Eur. J. Pharmacol. |
pmid:19022242
|
Dahlén SE |
Treatment of asthma with antileukotrienes: first line or last resort therapy? |
2006 |
Eur. J. Pharmacol. |
pmid:16510137
|
Hattori T et al. |
Effects of H2O2 on membrane potential of smooth muscle cells in rabbit mesenteric resistance artery. |
2003 |
Eur. J. Pharmacol. |
pmid:12620501
|
Hori M et al. |
NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. |
2009 |
Eur. J. Pharmacol. |
pmid:19616537
|
Sakata K and Bäck M |
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma. |
2002 |
Eur. J. Pharmacol. |
pmid:11834255
|
Sakai H et al. |
Augmented venous responsiveness to leukotriene D(4) in nasal septal mucosae of repeatedly antigen-challenged rats. |
2010 |
Eur. J. Pharmacol. |
pmid:20638382
|
Tsopanoglou NE et al. |
Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction. |
1994 |
Eur. J. Pharmacol. |
pmid:7523148
|
Takami M and Tsukada W |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents. |
1999 |
Eur. J. Pharmacol. |
pmid:10082207
|
Mizutani N et al. |
Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs. |
2008 |
Eur. J. Pharmacol. |
pmid:18191833
|
Arakawa H et al. |
Effect of maturation on airway plasma exudation induced by eicosanoids in guinea pig. |
1994 |
Eur. J. Pharmacol. |
pmid:7982451
|
Neves JS et al. |
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats. |
2005 |
Eur. J. Pharmacol. |
pmid:15792791
|
Ferrari F et al. |
Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity. |
2004 |
Eur. J. Pharmacol. |
pmid:15541426
|
Bäck M et al. |
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes. |
2000 |
Eur. J. Pharmacol. |
pmid:10936497
|
Kumasawa F et al. |
Apoptosis signal-regulating kinase 1 in leukotriene D(4)-induced activator protein-1 activation in airway smooth muscle cells. |
2005 |
Eur. J. Pharmacol. |
pmid:15970283
|
Bäck M et al. |
Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes. |
2000 |
Eur. J. Pharmacol. |
pmid:10936498
|
Gorenne I et al. |
Antagonism of leukotriene responses in human airways by BAY x7195. |
1995 |
Eur. J. Pharmacol. |
pmid:7796856
|
Saegusa S et al. |
Leukotriene D(4)-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells. |
2001 |
Eur. J. Pharmacol. |
pmid:11226389
|
Diener M and Scharrer E |
The leukotriene D4 receptor blocker, SK&F 104353, inhibits volume regulation in isolated crypts from the rat distal colon. |
1993 |
Eur. J. Pharmacol. |
pmid:8405093
|
Stengel PW et al. |
Inhaled anandamide reduces leukotriene D4-induced airway obstruction in guinea pigs. |
2007 |
Eur. J. Pharmacol. |
pmid:17166495
|
Fernandez J et al. |
Isoquercitrin from Argemone platyceras inhibits carbachol and leukotriene D4-induced contraction in guinea-pig airways. |
2005 |
Eur. J. Pharmacol. |
pmid:16202993
|
Tamaoka M et al. |
The epidermal growth factor receptor mediates allergic airway remodelling in the rat. |
2008 |
Eur. Respir. J. |
pmid:18653647
|
Ishikawa J et al. |
Involvement of endogenous tachykinins in LTD4-induced airway responses. |
1996 |
Eur. Respir. J. |
pmid:8730008
|
Kubes P |
Nitric oxide and microvascular permeability: a continuing dilemma. |
1997 |
Eur. Respir. J. |
pmid:9032483
|
Kageyama N et al. |
Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators. |
1997 |
Eur. Respir. J. |
pmid:9032485
|
Meliton AY et al. |
Leukotriene D4 activates {beta}2-integrin adhesion in human polymorphonuclear leukocytes. |
2010 |
Eur. Respir. J. |
pmid:19679609
|
Diamant Z et al. |
Effect of an inhaled neutral endopeptidase inhibitor, thiorphan, on airway responsiveness to leukotriene D4 in normal and asthmatic subjects. |
1994 |
Eur. Respir. J. |
pmid:8013602
|
Dahlén B et al. |
The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. |
1994 |
Eur. Respir. J. |
pmid:8162986
|
Casas A et al. |
Leukotriene D4-induced hypoxaemia in asthma is mediated by the cys-leukotriene1 receptor. |
2005 |
Eur. Respir. J. |
pmid:16135725
|
Salim T et al. |
The inflammatory mediator leukotriene D₄ induces subcellular β-catenin translocation and migration of colon cancer cells. |
2014 |
Exp. Cell Res. |
pmid:24211746
|
Massoumi R et al. |
Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin. |
2003 |
Exp. Cell Res. |
pmid:14499635
|
Thodeti CK et al. |
The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells. |
2001 |
Exp. Cell Res. |
pmid:11139333
|
Nielsen CK et al. |
Leukotriene D4 activates distinct G-proteins in intestinal epithelial cells to regulate stress fibre formation and to generate intracellular Ca2+ mobilisation and ERK1/2 activation. |
2005 |
Exp. Cell Res. |
pmid:15541723
|
Ramos-RamÃrez P et al. |
Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs. |
2013 |
Exp. Lung Res. |
pmid:23527782
|
McMahon B et al. |
Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation. |
2002 |
FASEB J. |
pmid:12223454
|
Carnini C et al. |
Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor. |
2011 |
FASEB J. |
pmid:21753081
|
Claesson HE et al. |
Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: novel insight into the inflammatory features of classical Hodgkin lymphoma. |
2008 |
FEBS J. |
pmid:18647347
|
Tanaka T et al. |
Protective effect of peptide leukotriene antagonist on renal failure induced by a tourniquet in rabbits. |
1995 |
Forensic Sci. Int. |
pmid:7875619
|
Kelley M et al. |
Induction of peroxisomal enzymes by a tetrazole-substituted 2-quinolinylmethoxy leukotriene D4 antagonist. |
1994 |
Fundam Appl Toxicol |
pmid:7982537
|
Bonnefoi MS et al. |
Subchronic toxicity studies with the leukotriene D4 antagonist RG 12525. |
1995 |
Fundam Appl Toxicol |
pmid:8566477
|
Martin CA et al. |
In vitro pharmacological effects of S 12370 (2-[4-benzhydryloxypiperidinoethyl]isoxindole; an antibronchoconstrictor agent) in normal and sensitized tissue. |
1996 |
Fundam Clin Pharmacol |
pmid:8902549
|
Honda I et al. |
Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction. |
1997 |
Fundam Clin Pharmacol |
pmid:9243258
|
Titos E et al. |
Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis. |
2000 |
Gastroenterology |
pmid:10982774
|
Kim N et al. |
Leukotriene D4-induced contraction of cat esophageal and lower esophageal sphincter circular smooth muscle. |
1998 |
Gastroenterology |
pmid:9753495
|
Ohd JF et al. |
Leukotrienes induce cell-survival signaling in intestinal epithelial cells. |
2000 |
Gastroenterology |
pmid:11040187
|
Huang XJ et al. |
Activation of CysLT receptors induces astrocyte proliferation and death after oxygen-glucose deprivation. |
2008 |
Glia |
pmid:17910051
|
Mion F et al. |
Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor. |
1994 |
Gut |
pmid:8174986
|
Wettstein M et al. |
Metabolism of cysteinyl leukotrienes in the perfused rat liver: the influence of endotoxin pretreatment and the cellular hydration state. |
1995 |
Hepatology |
pmid:7601416
|
Cincu RN et al. |
S-adenosyl-L-methionine protects the liver against the cholestatic, cytotoxic, and vasoactive effects of leukotriene D4: a study with isolated and perfused rat liver. |
1997 |
Hepatology |
pmid:9252142
|
Li X and Weinman SA |
Mrp2 modulates the activity of chloride channels in isolated hepatocytes. |
2002 |
Hepatology |
pmid:12085350
|
Wan D et al. |
The effects of montelukast on eosinophilic gastroenteritis in a mouse model. |
2013 |
Immunopharmacol Immunotoxicol |
pmid:23240855
|
Kodani M et al. |
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes. |
2000 |
Immunopharmacology |
pmid:10996024
|
Pelclová D et al. |
Leukotrienes B4, C4, D4 and E4 in the exhaled breath condensate (EBC), blood and urine in patients with pneumoconiosis. |
2012 |
Ind Health |
pmid:22785421
|
Sylvin H et al. |
Cysteinyl leukotrienes in porcine acute allergic airway reactions: bronchial and vascular effects. |
2003 |
Inflamm. Res. |
pmid:12813622
|
Theron AJ et al. |
Leukotrienes C4 and D4 sensitize human neutrophils for hyperreactivity to chemoattractants. |
2009 |
Inflamm. Res. |
pmid:19184354
|
Mehta KA et al. |
Release performance of a poorly soluble drug from a novel, Eudragit-based multi-unit erosion matrix. |
2001 |
Int J Pharm |
pmid:11165089
|
Carvajal MT and Staniforth JN |
Interactions of water with the surfaces of crystal polymorphs. |
2006 |
Int J Pharm |
pmid:16298501
|
Georgitis JW et al. |
Chronic sinusitis: characterization of cellular influx and inflammatory mediators in sinus lavage fluid. |
1995 |
Int. Arch. Allergy Immunol. |
pmid:7719157
|
Matsuse H et al. |
Differential airway inflammatory responses in asthma exacerbations induced by respiratory syncytial virus and influenza virus a. |
2013 |
Int. Arch. Allergy Immunol. |
pmid:23689185
|
Takami M et al. |
Possible role of thromboxane A2 in hyperresponsiveness of isolated rat lung tissue in a Sephadex-induced eosinophilia model. |
1995 |
Int. Arch. Allergy Immunol. |
pmid:7536504
|
Ohshima N et al. |
A functional study on CysLT(1) receptors in human eosinophils. |
2002 |
Int. Arch. Allergy Immunol. |
pmid:12373000
|
Kouyama S et al. |
A contraction assay system using primary cultured mouse bronchial smooth muscle cells. |
2013 |
Int. Arch. Allergy Immunol. |
pmid:23711859
|
Iwamoto I et al. |
Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs. |
1995 |
Int. Arch. Allergy Immunol. |
pmid:7647588
|
Hashimoto K et al. |
Cysteinyl leukotrienes induce monocyte chemoattractant protein-1 in human monocyte/macrophages via mitogen-activated protein kinase and nuclear factor-kappaB pathways. |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19218821
|
Mori M et al. |
Eosinophil superoxide anion generation induced by adhesion molecules and leukotriene D4. |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19494502
|
Morishima H et al. |
Ligation of Toll-like receptor 3 differentially regulates M2 and M3 muscarinic receptor expression and function in human airway smooth muscle cells. |
2008 |
Int. Arch. Allergy Immunol. |
pmid:17851256
|
Matsuse H et al. |
Naturally occurring parainfluenza virus 3 infection in adults induces mild exacerbation of asthma associated with increased sputum concentrations of cysteinyl leukotrienes. |
2005 |
Int. Arch. Allergy Immunol. |
pmid:16215328
|
Kang BC et al. |
Experimental asthma developed by room air contamination with cockroach allergen. |
1996 |
Int. Arch. Allergy Immunol. |
pmid:8917126
|
Tudorić N et al. |
Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. |
1994 |
Int. Arch. Allergy Immunol. |
pmid:8111247
|
Kawada N et al. |
The effect of leukotriene D(4) inhalation on the antigen-induced airway hyperresponsiveness and inflammation in 5-lipoxygenase gene-deficient mice. |
2001 |
Int. Arch. Allergy Immunol. |
pmid:11815738
|
Nagata M et al. |
Effect of the cysteinyl leukotriene antagonist pranlukast on transendothelial migration of eosinophils. |
2005 |
Int. Arch. Allergy Immunol. |
pmid:15947477
|
Kato Y et al. |
Leukotriene D4 induces production of transforming growth factor-beta1 by eosinophils. |
2005 |
Int. Arch. Allergy Immunol. |
pmid:15947480
|
Muraki M et al. |
Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication. |
2009 |
Int. Immunopharmacol. |
pmid:19706339
|
RodrÃguez-Lagunas MJ et al. |
5-Hydroxyeicosatetraenoic acid and leukotriene D4 increase intestinal epithelial paracellular permeability. |
2013 |
Int. J. Biochem. Cell Biol. |
pmid:23583294
|
Schain F et al. |
Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma. |
2008 |
Int. J. Cancer |
pmid:18704935
|
Meier HL et al. |
Simultaneous initiation of degranulation and inhibition of leukotriene release by soman in human basophils. |
1995 |
Int. J. Immunopharmacol. |
pmid:7545649
|
Daugschies A and Ruttkowski B |
Modulation of migration of Oesophagostomum dentatum larvae by inhibitors and products of eicosanoid metabolism. |
1998 |
Int. J. Parasitol. |
pmid:9513001
|
Krauss AH and Woodward DF |
Polymorphonuclear leukocyte infiltration into the subretinal choroid and optic nerve in response to leukotrienes. |
1993 |
Invest. Ophthalmol. Vis. Sci. |
pmid:8258528
|
Sciuto AM et al. |
Post-exposure treatment with isoproterenol attenuates pulmonary edema in phosgene-exposed rabbits. |
1998 Sep-Oct |
J Appl Toxicol |
pmid:9804432
|
Kjellström S et al. |
On-line coupling of microdialysis sampling with liquid chromatography for the determination of peptide and non-peptide leukotrienes. |
1998 |
J Chromatogr A |
pmid:9818423
|
Mehta KA et al. |
Effect of formulation and process variables on porosity parameters and release rates from a multi unit erosion matrix of a poorly soluble drug. |
2000 |
J Control Release |
pmid:10640593
|
Campos MG et al. |
Galphimia glauca organic fraction antagonizes LTD(4)-induced contraction in guinea pig airways. |
2001 |
J Ethnopharmacol |
pmid:11137344
|