Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Aspergillosis, Allergic Bronchopulmonary D001229 2 associated lipids
Sneezing D012912 6 associated lipids
Asbestosis D001195 8 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Airway Obstruction D000402 13 associated lipids
Carotid Stenosis D016893 15 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Endotoxemia D019446 27 associated lipids
Glomerulonephritis D005921 35 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Leukemia D007938 74 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Per page 10 20 50 100 | Total 562
Authors Title Published Journal PubMed Link
Takano T et al. Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. 1997 J. Exp. Med. pmid:9151906
Beckh K et al. Effects of nitric oxide on leukotriene D4 decreased bile secretion in the perfused rat liver. 1997 Life Sci. pmid:9364199
Gissurarson SR et al. Effect of lobaric acid on cysteinyl-leukotriene formation and contractile activity of guinea pig taenia coli. 1997 J. Pharmacol. Exp. Ther. pmid:9023290
Wang Y et al. Induction of LTD in the dentate gyrus in vitro is NMDA receptor independent, but dependent on Ca2+ influx via low-voltage-activated Ca2+ channels and release of Ca2+ from intracellular stores. 1997 J. Neurophysiol. pmid:9065852
Kubes P Nitric oxide and microvascular permeability: a continuing dilemma. 1997 Eur. Respir. J. pmid:9032483
Kageyama N et al. Role of endogenous nitric oxide in airway microvascular leakage induced by inflammatory mediators. 1997 Eur. Respir. J. pmid:9032485
Tvaermose-Nielsen O et al. Discovery of OT4003, a novel, potent, and orally active cys-LT1 receptor antagonist. 1997 Bioorg. Med. Chem. pmid:9061206
Honda I et al. Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction. 1997 Fundam Clin Pharmacol pmid:9243258
Yamaya M et al. Dipeptidase inhibitor and epithelial removal potentiate leukotriene D4-induced human tracheal smooth muscle contraction. 1998 Respir Physiol pmid:9496476
Arakida Y et al. In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors. 1998 J. Pharmacol. Exp. Ther. pmid:9808690
Chambers RJ et al. Development of new chromanol antagonists of leukotriene D4. 1998 Bioorg. Med. Chem. Lett. pmid:9873435
Tsang F et al. Effects of mitogen-activated protein kinase kinase inhibitor PD 098059 on antigen challenge of guinea-pig airways in vitro. 1998 Br. J. Pharmacol. pmid:9776345
Lane SJ Leukotriene antagonism in asthma and rhinitis. 1998 Respir Med pmid:9850362
Liu YC et al. Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin-sensitized guinea-pigs in vitro. 1998 Br. J. Pharmacol. pmid:9647482
Ohbayashi H et al. Neutral endopeptidase 3.4.24.11 inhibition potentiates the inhibitory effects of type-C natriuretic peptide on leukotriene D4-induced airway changes. 1998 Clin. Exp. Pharmacol. Physiol. pmid:9887994
Underwood DC et al. Antiasthmatic activity of the second-generation phosphodiesterase 4 (PDE4) inhibitor SB 207499 (Ariflo) in the guinea pig. 1998 J. Pharmacol. Exp. Ther. pmid:9864284
Fujimura M et al. A partial involvement of histamine in ultrasonically nebulized distilled water-induced bronchoconstriction in guinea-pigs. 1998 Br. J. Pharmacol. pmid:9831931
Allen S et al. Differential leukotriene constrictor responses in human atherosclerotic coronary arteries. 1998 Circulation pmid:9641692
Sato E et al. Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. 1998 Am. J. Physiol. pmid:9609736
Daugschies A and Ruttkowski B Modulation of migration of Oesophagostomum dentatum larvae by inhibitors and products of eicosanoid metabolism. 1998 Int. J. Parasitol. pmid:9513001