| MeSH term | MeSH ID | Detail |
|---|---|---|
| Endotoxemia | D019446 | 27 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| Sneezing | D012912 | 6 associated lipids |
| Respiratory Hypersensitivity | D012130 | 18 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Aspergillosis, Allergic Bronchopulmonary | D001229 | 2 associated lipids |
| Asbestosis | D001195 | 8 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
Ltd4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ltd4?
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ltd4
PubChem Associated disorders and diseases
What pathways are associated with Ltd4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ltd4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Ltd4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ltd4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Ltd4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ltd4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Ltd4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bouchelouche K et al. | The action of cysteinyl-leukotrienes on intracellular calcium mobilization in human detrusor myocytes. | 2001 | BJU Int. | pmid:11350414 |
| Massoumi R and Sjölander A | Leukotriene D(4) affects localisation of vinculin in intestinal epithelial cells via distinct tyrosine kinase and protein kinase C controlled events. | 2001 | J. Cell. Sci. | pmid:11329379 |
| Aoki M et al. | Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11259541 |
| Saegusa S et al. | Leukotriene D(4)-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells. | 2001 | Eur. J. Pharmacol. | pmid:11226389 |
| Maekawa A et al. | Identification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicing. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11226226 |
| Tohda Y et al. | Role of chemical mediators in airway hyperresponsiveness in an asthmatic model. | 2001 | Respiration | pmid:11223734 |
| Accomazzo MR et al. | Leukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent. | 2001 | Am. J. Respir. Crit. Care Med. | pmid:11208655 |
| Simons FE et al. | Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11206237 |
| Kivity S et al. | Eosinophil influx into the airways in patients with exercise-induced asthma. | 2000 | Respir Med | pmid:11192956 |
| Mehta KA et al. | Release performance of a poorly soluble drug from a novel, Eudragit-based multi-unit erosion matrix. | 2001 | Int J Pharm | pmid:11165089 |
| Hele DJ et al. | Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. | 2001 | Br. J. Pharmacol. | pmid:11159698 |
| Gronert K et al. | Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. | 2001 | Am. J. Pathol. | pmid:11141472 |
| Thodeti CK et al. | The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells. | 2001 | Exp. Cell Res. | pmid:11139333 |
| Campos MG et al. | Galphimia glauca organic fraction antagonizes LTD(4)-induced contraction in guinea pig airways. | 2001 | J Ethnopharmacol | pmid:11137344 |
| Robbiani DF et al. | The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. | 2000 | Cell | pmid:11114332 |
| Hisamatsu K and Nakajima M | Pranlukast protects leukotriene C4- and D4-induced epithelial cell impairment of the nasal mucosa in vitro. | 2000 | Life Sci. | pmid:11105993 |
| Nothacker HP et al. | Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. | 2000 | Mol. Pharmacol. | pmid:11093801 |
| Kalf GF | Utility of a mouse model for studying the effects of benzene on the myeloid lineage: effects of hydroquinone on a model myeloid system. | 2000 | J. Toxicol. Environ. Health Part A | pmid:11086946 |
| Babu KS and Salvi SS | Aspirin and asthma. | 2000 | Chest | pmid:11083703 |
| Thivierge M et al. | IL-5 up-regulates cysteinyl leukotriene 1 receptor expression in HL-60 cells differentiated into eosinophils. | 2000 | J. Immunol. | pmid:11046055 |
| Ohd JF et al. | Leukotrienes induce cell-survival signaling in intestinal epithelial cells. | 2000 | Gastroenterology | pmid:11040187 |
| Ménard G and Bissonnette EY | Priming of alveolar macrophages by leukotriene D(4): potentiation of inflammation. | 2000 | Am. J. Respir. Cell Mol. Biol. | pmid:11017925 |
| Kodani M et al. | Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes. | 2000 | Immunopharmacology | pmid:10996024 |
| Titos E et al. | Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis. | 2000 | Gastroenterology | pmid:10982774 |
| Bäck M et al. | Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes. | 2000 | Eur. J. Pharmacol. | pmid:10936498 |
| Bäck M et al. | Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes. | 2000 | Eur. J. Pharmacol. | pmid:10936497 |
| Turner DJ et al. | Bradykinin-induced airway constriction in guinea-pigs: role of leukotriene D(4). | 2000 | Pulm Pharmacol Ther | pmid:10930357 |
| Takasaki J et al. | The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10913337 |
| Blain JF and Sirois P | Involvement of LTD(4)in allergic pulmonary inflammation in mice: modulation by cysLT(1)antagonist MK-571. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10913229 |
| Mayatepek E et al. | Defects in the synthesis of cysteinyl leukotrienes: a new group of inborn errors of metabolism. | 2000 | J. Inherit. Metab. Dis. | pmid:10896305 |
| Lopes LR et al. | Reduced inflammatory response in rats fed fat-rich diets: role of leukotrienes. | 2000 | Life Sci. | pmid:10896024 |
| Arakida Y et al. | In vivo pharmacologic profile of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors. | 2000 | Jpn. J. Pharmacol. | pmid:10887942 |
| McMahon B et al. | Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors. | 2000 | J. Biol. Chem. | pmid:10869343 |
| Ballart B et al. | Synthesis and pharmacological evaluation of new 4-2-(7-heterocyclemethoxynaftalen-2-ylmethoxy)ethylbenzoic acids as LTD(4)-antagonists. | 2000 | Eur J Med Chem | pmid:10858604 |
| Davis HM et al. | Human granulocyte CD11b expression as a pharmacodynamic biomarker of inflammation. | 2000 | J. Immunol. Methods | pmid:10854607 |
| Fukuyama S et al. | Effect of eotaxin and platelet-activating factor on airway inflammation and hyperresponsiveness in guinea pigs in vivo. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:10852755 |
| Heise CE et al. | Characterization of the human cysteinyl leukotriene 2 receptor. | 2000 | J. Biol. Chem. | pmid:10851239 |
| Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |
| Ravasi S et al. | A kinetic binding study to evaluate the pharmacological profile of a specific leukotriene C(4) binding site not coupled to contraction in human lung parenchyma. | 2000 | Mol. Pharmacol. | pmid:10825389 |
| Macfarlane AJ et al. | Sputum cysteinyl leukotrienes increase 24 hours after allergen inhalation in atopic asthmatics. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:10806153 |
| Ahmed T et al. | Inhibition of allergic late airway responses by inhaled heparin-derived oligosaccharides. | 2000 | J. Appl. Physiol. | pmid:10797135 |
| Underwood DC et al. | SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734180 |
| Thodeti CK et al. | Leukotriene D(4) triggers an association between gbetagamma subunits and phospholipase C-gamma1 in intestinal epithelial cells. | 2000 | J. Biol. Chem. | pmid:10734140 |
| Laberge S et al. | Antigen-induced airway inflammation and hyper-responsiveness does not enhance airway responses to a subsequent antigen challenge in rats. | 2000 | Respir Med | pmid:10714478 |
| Mayatepek E et al. | Analysis of leukotrienes in cerebrospinal fluid of a reference population and patients with inborn errors of metabolism: further evidence for a pathognomonic profile in LTC(4)-synthesis deficiency. | 2000 | Clin. Chim. Acta | pmid:10686285 |
| Mehta KA et al. | Effect of formulation and process variables on porosity parameters and release rates from a multi unit erosion matrix of a poorly soluble drug. | 2000 | J Control Release | pmid:10640593 |
| Yamashita T and Kokubun S | Nonselective cationic currents activated by acetylcholine in swine tracheal smooth muscle cells. | 1999 | Can. J. Physiol. Pharmacol. | pmid:10588484 |
| Yang XX et al. | The beta(2)-agonist salbutamol inhibits bronchoconstriction and leukotriene D(4) synthesis after dry gas hyperpnea in the guinea-pig. | 1999 | Pulm Pharmacol Ther | pmid:10545287 |
| Lankisch TO et al. | High-affinity cholecystokinin type A receptor/cytosolic phospholipase A2 pathways mediate Ca2+ oscillations via a positive feedback regulation by calmodulin kinase in pancreatic acini. | 1999 | Eur. J. Cell Biol. | pmid:10535305 |
| Sarau HM et al. | Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor. | 1999 | Mol. Pharmacol. | pmid:10462554 |