MeSH term | MeSH ID | Detail |
---|---|---|
Leukemia | D007938 | 74 associated lipids |
Edema | D004487 | 152 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Ltd4
MeSH term | MeSH ID | Detail |
---|---|---|
Leukemia | D007938 | 74 associated lipids |
Edema | D004487 | 152 associated lipids |
Colonic Neoplasms | D003110 | 161 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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O'Brien E et al. | Bisphenol A at concentrations relevant to human exposure enhances histamine and cysteinyl leukotriene release from bone marrow-derived mast cells. | 2014 Jan-Mar | J Immunotoxicol | pmid:23782309 |
Bellamkonda K et al. | The impact of inflammatory lipid mediators on colon cancer-initiating cells. | 2015 | Mol. Carcinog. | pmid:25154976 |
Al-Husseini A et al. | Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. | 2015 | PLoS ONE | pmid:25785937 |
Sekioka T et al. | Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction. | 2015 | Allergol Int | pmid:26433531 |
Noguchi T et al. | Effect of beta2-adrenergic agonists on eosinophil adhesion, superoxide anion generation, and degranulation. | 2015 | Allergol Int | pmid:26344080 |
Al-Azzam N et al. | Modulation of mast cell proliferative and inflammatory responses by leukotriene d4 and stem cell factor signaling interactions. | 2015 | J. Cell. Physiol. | pmid:25161061 |
Kondeti V et al. | Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3. | 2016 | J. Allergy Clin. Immunol. | pmid:26255103 |
Rael E | Unraveling the complexity of leukotriene and prostaglandin inflammatory signaling. | 2016 | J. Allergy Clin. Immunol. | pmid:26518091 |
Lukic A et al. | Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4. | 2016 | J. Lipid Res. | pmid:27436590 |
Khaddaj-Mallat R et al. | Pro-Resolving Effects of Resolvin D2 in LTD4 and TNF-α Pre-Treated Human Bronchi. | 2016 | PLoS ONE | pmid:27935998 |
Bellamkonda K et al. | The eicosanoids leukotriene D4 and prostaglandin E2 promote the tumorigenicity of colon cancer-initiating cells in a xenograft mouse model. | 2016 | BMC Cancer | pmid:27388564 |
Park SY et al. | Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer. | 2016 | Oncotarget | pmid:26824987 |