| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia | D007938 | 74 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Ltd4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ltd4?
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ltd4
PubChem Associated disorders and diseases
What pathways are associated with Ltd4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ltd4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ltd4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ltd4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ltd4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ltd4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Ltd4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hirata F et al. | IL-1 beta regulates the expression of the Gi2 alpha gene via lipid mediators in guinea pig tracheal muscle. | 1994 | Biochem. Biophys. Res. Commun. | pmid:7945342 |
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| Undem BJ et al. | Recombinant stem cell factor-induced mast cell activation and smooth muscle contraction in human bronchi. | 1994 | Am. J. Respir. Cell Mol. Biol. | pmid:7524570 |
| Tudhope SR et al. | BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. | 1994 | Eur. J. Pharmacol. | pmid:7698171 |
| Ibe BO et al. | Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. | 1994 | Eur. J. Clin. Invest. | pmid:8187808 |
| Fauler J et al. | Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. | 1994 | Arthritis Rheum. | pmid:8129769 |
| Sjölander A and Grönroos E | Leukotriene D4-induced signal transduction. | 1994 | Ann. N. Y. Acad. Sci. | pmid:7825836 |
| Krell RD et al. | Preclinical exploration of the potential antiinflammatory properties of the peptide leukotriene antagonist ICI 204,219 (Accolate). | 1994 | Ann. N. Y. Acad. Sci. | pmid:7825851 |
| An S et al. | Molecular cloning of sheep lung dipeptidase: a glycosyl phosphatidylinositol-anchored ectoenzyme that converts leukotriene D4 to leukotriene E4. | 1994 | Biochim. Biophys. Acta | pmid:8054366 |
| Tsopanoglou NE et al. | Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction. | 1994 | Eur. J. Pharmacol. | pmid:7523148 |
| Underwood DC et al. | Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8035322 |
| Metters KM et al. | Characterization of specific binding sites for cysteinyl leukotrienes in sheep lung. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8035338 |
| Chan CC et al. | Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8014876 |
| Arakawa H et al. | Effect of maturation on airway plasma exudation induced by eicosanoids in guinea pig. | 1994 | Eur. J. Pharmacol. | pmid:7982451 |
| Kelley M et al. | Induction of peroxisomal enzymes by a tetrazole-substituted 2-quinolinylmethoxy leukotriene D4 antagonist. | 1994 | Fundam Appl Toxicol | pmid:7982537 |
| Ellis JL and Undem BJ | Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8111568 |
| Tudorić N et al. | Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. | 1994 | Int. Arch. Allergy Immunol. | pmid:8111247 |
| Kurosawa M et al. | Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs. | 1994 | Clin. Exp. Allergy | pmid:7842366 |
| Oliva D et al. | Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301553 |
| Kano M | Calcium-induced long-lasting potentiation of GABAergic currents in cerebellar Purkinje cells. | 1994 | Jpn. J. Physiol. | pmid:7752516 |
| Georgitis JW et al. | Chronic sinusitis: characterization of cellular influx and inflammatory mediators in sinus lavage fluid. | 1995 | Int. Arch. Allergy Immunol. | pmid:7719157 |
| Takami M et al. | Possible role of thromboxane A2 in hyperresponsiveness of isolated rat lung tissue in a Sephadex-induced eosinophilia model. | 1995 | Int. Arch. Allergy Immunol. | pmid:7536504 |
| Grönroos E et al. | The regulation of leukotriene D4-induced calcium influx in human epithelial cells involves protein tyrosine phosphorylation. | 1995 | Cell Calcium | pmid:7621531 |
| Meier HL et al. | Simultaneous initiation of degranulation and inhibition of leukotriene release by soman in human basophils. | 1995 | Int. J. Immunopharmacol. | pmid:7545649 |
| Porreca E et al. | Modulation of rat vascular smooth muscle cell (VSMC) proliferation by cysteinyl leukotriene D4: a role for mediation of interleukin 1. | 1995 | Atherosclerosis | pmid:7755646 |
| Hazel BA et al. | Benzene and its metabolite, hydroquinone, induce granulocytic differentiation in myeloblasts by interacting with cellular signaling pathways activated by granulocyte colony-stimulating factor. | 1995 | Stem Cells | pmid:7542115 |
| Cohen P et al. | Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis. | 1995 | Am. J. Physiol. | pmid:7544535 |
| Iwamoto I et al. | Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs. | 1995 | Int. Arch. Allergy Immunol. | pmid:7647588 |
| Patel JP et al. | Beneficial effects of combined thromboxane and leukotriene receptor antagonism in hemorrhagic shock. | 1995 | Crit. Care Med. | pmid:7867347 |
| Kelefiotis D et al. | Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. | 1995 | Prostaglandins | pmid:7659782 |
| Donnelly AL et al. | The leukotriene D4-receptor antagonist, ICI 204,219, relieves symptoms of acute seasonal allergic rhinitis. | 1995 | Am. J. Respir. Crit. Care Med. | pmid:7767514 |
| Smit NP et al. | Stimulation of cultured melanocytes in medium containing a serum substitute: Ultroser-G. | 1995 | Pigment Cell Res. | pmid:7540755 |
| Tanaka T et al. | Protective effect of peptide leukotriene antagonist on renal failure induced by a tourniquet in rabbits. | 1995 | Forensic Sci. Int. | pmid:7875619 |
| Ganbo T et al. | Inhibition of mucociliary clearance of the eustachian tube by leukotrienes C4 and D4. | 1995 | Ann. Otol. Rhinol. Laryngol. | pmid:7872607 |
| Kanwar S et al. | Leukotriene C4/D4 induces P-selectin and sialyl Lewis(x)-dependent alterations in leukocyte kinetics in vivo. | 1995 | Circ. Res. | pmid:7554141 |
| Fiorucci S et al. | Effect of NSAIDs on pepsinogen secretion and calcium mobilization in isolated chief cells. | 1995 | Am. J. Physiol. | pmid:7611418 |
| Ramondt J et al. | Sensitivity of ovine myometrial tissue to various eicosanoids in vitro. | 1995 | Prostaglandins | pmid:7792392 |
| Herron DK et al. | Visualization and comparison of molecular dynamics simulations of leukotriene C4, leukotriene D4, and leukotriene E4. | 1995 | J Mol Graph | pmid:8820302 |
| Gorenne I et al. | Antagonism of leukotriene responses in human airways by BAY x7195. | 1995 | Eur. J. Pharmacol. | pmid:7796856 |
| Powell WS et al. | Effects of dexamethasone on leukotriene synthesis and airway responses to antigen and leukotriene D4 in rats. | 1995 | Am. J. Respir. Crit. Care Med. | pmid:7697244 |
| Gronert K et al. | Endogenous sulfidopeptide leukotriene synthesis and 12-lipoxygenase activity in bullfrog (Rana catesbeiana) erythrocytes. | 1995 | Biochim. Biophys. Acta | pmid:7734448 |
| Porreca E et al. | Cysteinyl-leukotriene D4 induced IL-1 beta expression and release in rat vascular smooth muscle cells. | 1995 | Atherosclerosis | pmid:7661877 |
| Langer JC et al. | Mast cell mediators and peritoneal adhesion formation in the rat. | 1995 | J. Surg. Res. | pmid:7643592 |
| Weiss SR et al. | Quenching: inhibition of development and expression of amygdala kindled seizures with low frequency stimulation. | 1995 | Neuroreport | pmid:8595196 |
| Ganbo T et al. | The effects of leukotrienes C4 and D4 on ciliary activity of human paranasal sinus mucosa in vitro. | 1995 | Rhinology | pmid:8919211 |
| Tudoric N et al. | Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea. | 1995 | Acta Anaesthesiol Scand | pmid:8607320 |
| Ortiz JL et al. | Leukotriene receptors on human pulmonary vascular endothelium. | 1995 | Br. J. Pharmacol. | pmid:8564195 |
| Bonnefoi MS et al. | Subchronic toxicity studies with the leukotriene D4 antagonist RG 12525. | 1995 | Fundam Appl Toxicol | pmid:8566477 |
| Wood-Baker R et al. | The reproducibility and effect on non-specific airway responsiveness of inhaled prostaglandin D2 and leukotriene D4 in asthmatic subjects. | 1995 | Br J Clin Pharmacol | pmid:7742148 |
| Madsen F et al. | Challenge interval determines tachyphylaxis to aerosolized LTD4. | 1995 | Pulm Pharmacol | pmid:8819178 |