| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia | D007938 | 74 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Ltd4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ltd4?
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ltd4
PubChem Associated disorders and diseases
What pathways are associated with Ltd4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ltd4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ltd4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ltd4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ltd4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ltd4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Ltd4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ganbo T et al. | Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. | 1996 | Am. J. Physiol. | pmid:8770059 |
| Carlton RA et al. | Preparation and characterization of polymorphs for an LTD4 antagonist, RG 12525. | 1996 | J Pharm Sci | pmid:8742935 |
| Ishikawa J et al. | Involvement of endogenous tachykinins in LTD4-induced airway responses. | 1996 | Eur. Respir. J. | pmid:8730008 |
| Konno A et al. | Role of substance P in the vascular response of nasal mucosa in nasal allergy. | 1996 | Ann. Otol. Rhinol. Laryngol. | pmid:8712637 |
| Datta HK et al. | Parathyroid hormone induces superoxide anion burst in the osteoclast: evidence for the direct instantaneous activation of the osteoclast by the hormone. | 1996 | J. Endocrinol. | pmid:8708538 |
| Funayama T et al. | Role of Leukotriene-degrading enzymes in pulmonary response to antigen infusion in sensitized guinea pigs in vivo. | 1996 | Am. J. Respir. Cell Mol. Biol. | pmid:8703483 |
| Papayianni A et al. | Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. | 1996 | J. Immunol. | pmid:8690917 |
| Dudek SM and Friedlander MJ | Developmental down-regulation of LTD in cortical layer IV and its independence of modulation by inhibition. | 1996 | Neuron | pmid:8663986 |
| Grönroos E et al. | Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. | 1996 | Biochem. J. | pmid:8645211 |
| Heimbürger M and Palmblad JE | Effects of leukotriene C4 and D4, histamine and bradykinin on cytosolic calcium concentrations and adhesiveness of endothelial cells and neutrophils. | 1996 | Clin. Exp. Immunol. | pmid:8608646 |
| Tudoric N et al. | Effects of halothane and isoflurane on antigen- and leukotriene-D4-induced constriction of guinea pig trachea. | 1995 | Acta Anaesthesiol Scand | pmid:8607320 |
| Weiss SR et al. | Quenching: inhibition of development and expression of amygdala kindled seizures with low frequency stimulation. | 1995 | Neuroreport | pmid:8595196 |
| Bonnefoi MS et al. | Subchronic toxicity studies with the leukotriene D4 antagonist RG 12525. | 1995 | Fundam Appl Toxicol | pmid:8566477 |
| Ortiz JL et al. | Leukotriene receptors on human pulmonary vascular endothelium. | 1995 | Br. J. Pharmacol. | pmid:8564195 |
| Chen C et al. | Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. | 1995 | Cell | pmid:8548809 |
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| Shikada K and Tanaka S | Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121. | 1993 | Br. J. Pharmacol. | pmid:8401920 |
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| Nathan RA et al. | Inhaled ICI 204,219 blocks antigen-induced bronchoconstriction in subjects with bronchial asthma. | 1994 | Chest | pmid:8306751 |
| Lee TH and Christie PE | Leukotrienes and aspirin induced asthma. | 1993 | Thorax | pmid:8303620 |
| Howell RE et al. | Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301576 |
| Oliva D et al. | Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8301553 |
| Krauss AH et al. | Determination of leukotriene effects on human neutrophil chemotaxis in vitro by differential assessment of cell motility and polarity. | 1994 | J. Leukoc. Biol. | pmid:8301217 |
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| Krauss AH and Woodward DF | Polymorphonuclear leukocyte infiltration into the subretinal choroid and optic nerve in response to leukotrienes. | 1993 | Invest. Ophthalmol. Vis. Sci. | pmid:8258528 |
| Yoshikawa S et al. | Modulation of acetylcholine release from the myenteric plexus of guinea-pig ileum by 5-lipoxygenase metabolites of arachidonic acid. | 1993 | Eur. J. Pharmacol. | pmid:8223906 |
| Smith LJ et al. | Inhibition of leukotriene D4-induced bronchoconstriction in subjects with asthma: a concentration-effect study of ICI 204,219. | 1993 | Clin. Pharmacol. Ther. | pmid:8222486 |
| Arakawa H et al. | Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor. | 1993 | Br. J. Pharmacol. | pmid:8220872 |
| Manning PJ et al. | Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms. | 1993 | Am. Rev. Respir. Dis. | pmid:8214949 |
| Pawloski JR and Chapnick BM | Antagonism of LTD4-evoked relaxation in canine renal artery and vein. | 1993 | Am. J. Physiol. | pmid:8214135 |
| Hyun CS and Binder HJ | Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. | 1993 | Am. J. Physiol. | pmid:8214069 |
| Han H et al. | Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. | 1994 | Am. J. Physiol. | pmid:8203604 |
| Kargman S et al. | Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells. | 1994 | Mol. Pharmacol. | pmid:8190095 |
| Ibe BO et al. | Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. | 1994 | Eur. J. Clin. Invest. | pmid:8187808 |
| Salari H et al. | Involvement of immunologic mechanisms in a guinea pig model of western red cedar asthma. | 1994 | J. Allergy Clin. Immunol. | pmid:8182231 |
| Abela A and Daniel EE | Neural and myogenic effects of leukotrienes C4, D4, and E4 on canine bronchial smooth muscle. | 1994 | Am. J. Physiol. | pmid:8179018 |
| Mion F et al. | Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor. | 1994 | Gut | pmid:8174986 |
| Dahlén B et al. | The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. | 1994 | Eur. Respir. J. | pmid:8162986 |
| Fauler J et al. | Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. | 1994 | Arthritis Rheum. | pmid:8129769 |
| Ramis I et al. | Application of totally automated on-line sample clean up system for extraction and high-performance liquid chromatography separation of peptide leukotrienes. | 1993 Nov-Dec | J Pharm Biomed Anal | pmid:8123725 |
| Weide I et al. | Intravascular cysteinyl-leukotriene formation by clotting whole human blood. Evidence from clamped umbilical vein segments and thrombus specimens. | 1993 | Thromb. Res. | pmid:8122190 |
| Ellis JL and Undem BJ | Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. | 1994 | Am. J. Respir. Crit. Care Med. | pmid:8111568 |
| Tudorić N et al. | Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. | 1994 | Int. Arch. Allergy Immunol. | pmid:8111247 |
| Nakazawa T et al. | Leukotriene D4-induced mucosal damage during long observation periods in vitro. | 1994 | Prostaglandins | pmid:8066186 |
| An S et al. | Molecular cloning of sheep lung dipeptidase: a glycosyl phosphatidylinositol-anchored ectoenzyme that converts leukotriene D4 to leukotriene E4. | 1994 | Biochim. Biophys. Acta | pmid:8054366 |
| Metters KM et al. | Characterization of specific binding sites for cysteinyl leukotrienes in sheep lung. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8035338 |
| Underwood DC et al. | Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8035322 |
| Herd CM et al. | Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits. | 1994 | Br. J. Pharmacol. | pmid:8032653 |
| Hoheisel U and Mense S | Leukotriene D4 depresses the mechanosensitivity of group III and IV muscle receptors in the rat. | 1994 | Neuroreport | pmid:8025261 |
| Chan CC et al. | Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists. | 1994 | J. Pharmacol. Exp. Ther. | pmid:8014876 |