Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

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Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Authors Title Published Journal PubMed Link
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Titos E et al. Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis. 2000 Gastroenterology pmid:10982774
Ménard G and Bissonnette EY Priming of alveolar macrophages by leukotriene D(4): potentiation of inflammation. 2000 Am. J. Respir. Cell Mol. Biol. pmid:11017925
Arakida Y et al. In vivo pharmacologic profile of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors. 2000 Jpn. J. Pharmacol. pmid:10887942
McMahon B et al. Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors. 2000 J. Biol. Chem. pmid:10869343
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Kivity S et al. Eosinophil influx into the airways in patients with exercise-induced asthma. 2000 Respir Med pmid:11192956
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Ohd JF et al. Leukotrienes induce cell-survival signaling in intestinal epithelial cells. 2000 Gastroenterology pmid:11040187
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Kodani M et al. Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes. 2000 Immunopharmacology pmid:10996024
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Takasaki J et al. The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor. 2000 Biochem. Biophys. Res. Commun. pmid:10913337