MeSH term | MeSH ID | Detail |
---|---|---|
Asbestosis | D001195 | 8 associated lipids |
Sneezing | D012912 | 6 associated lipids |
Aspergillosis, Allergic Bronchopulmonary | D001229 | 2 associated lipids |
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Ltd4
MeSH term | MeSH ID | Detail |
---|---|---|
Asbestosis | D001195 | 8 associated lipids |
Sneezing | D012912 | 6 associated lipids |
Aspergillosis, Allergic Bronchopulmonary | D001229 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cohen P et al. | Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis. | 1995 | Am. J. Physiol. | pmid:7544535 |
Goldhill J et al. | Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle. | 1997 | Am. J. Physiol. | pmid:9176223 |
Rajah R et al. | Leukotriene D4 induces MMP-1, which functions as an IGFBP protease in human airway smooth muscle cells. | 1996 | Am. J. Physiol. | pmid:8997273 |
Olszewski MA et al. | Mediators of anaphylaxis but not activated neutrophils augment cholinergic responses of equine small airways. | 1999 | Am. J. Physiol. | pmid:10070118 |
Hyun CS and Binder HJ | Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. | 1993 | Am. J. Physiol. | pmid:8214069 |
Pawloski JR and Chapnick BM | Antagonism of LTD4-evoked relaxation in canine renal artery and vein. | 1993 | Am. J. Physiol. | pmid:8214135 |
Fiorucci S et al. | Effect of NSAIDs on pepsinogen secretion and calcium mobilization in isolated chief cells. | 1995 | Am. J. Physiol. | pmid:7611418 |
Sato E et al. | Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. | 1998 | Am. J. Physiol. | pmid:9609736 |
Han H et al. | Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. | 1994 | Am. J. Physiol. | pmid:8203604 |
Ganbo T et al. | Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. | 1996 | Am. J. Physiol. | pmid:8770059 |