MeSH term | MeSH ID | Detail |
---|---|---|
Asbestosis | D001195 | 8 associated lipids |
Sneezing | D012912 | 6 associated lipids |
Aspergillosis, Allergic Bronchopulmonary | D001229 | 2 associated lipids |
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Ltd4
MeSH term | MeSH ID | Detail |
---|---|---|
Asbestosis | D001195 | 8 associated lipids |
Sneezing | D012912 | 6 associated lipids |
Aspergillosis, Allergic Bronchopulmonary | D001229 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Parmentier CN et al. | Human T(H)2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1. | 2012 | J. Allergy Clin. Immunol. | pmid:22391114 |
Rehn M and Diener M | Cysteinyl leukotrienes mediate the response of submucosal ganglia from rat colon to bradykinin. | 2012 | Eur. J. Pharmacol. | pmid:22366210 |
Mizutani N et al. | Effect of Ganoderma lucidum on pollen-induced biphasic nasal blockage in a guinea pig model of allergic rhinitis. | 2012 | Phytother Res | pmid:21698671 |
Matsumoto H et al. | Interleukin-13 enhanced Ca2+ oscillations in airway smooth muscle cells. | 2012 | Cytokine | pmid:22078634 |
Drost AC et al. | The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia. | 2012 | Leuk. Lymphoma | pmid:21936770 |
Yan D et al. | Differential signaling of cysteinyl leukotrienes and a novel cysteinyl leukotriene receptor 2 (CysLT₂) agonist, N-methyl-leukotriene C₄, in calcium reporter and β arrestin assays. | 2011 | Mol. Pharmacol. | pmid:21078884 |
Daniele S et al. | Agonist-induced desensitization/resensitization of human G protein-coupled receptor 17: a functional cross-talk between purinergic and cysteinyl-leukotriene ligands. | 2011 | J. Pharmacol. Exp. Ther. | pmid:21531793 |
Carnini C et al. | Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor. | 2011 | FASEB J. | pmid:21753081 |
Ni NC et al. | A selective cysteinyl leukotriene receptor 2 antagonist blocks myocardial ischemia/reperfusion injury and vascular permeability in mice. | 2011 | J. Pharmacol. Exp. Ther. | pmid:21903747 |
Chen LY et al. | Cooperative and redundant signaling of leukotriene B4 and leukotriene D4 in human monocytes. | 2011 | Allergy | pmid:21605126 |