Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Asbestosis D001195 8 associated lipids
Sneezing D012912 6 associated lipids
Aspergillosis, Allergic Bronchopulmonary D001229 2 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Authors Title Published Journal PubMed Link
Meliton AY et al. Leukotriene D4 activates {beta}2-integrin adhesion in human polymorphonuclear leukocytes. 2010 Eur. Respir. J. pmid:19679609
Julius P et al. sCD14 in bronchoalveolar lavage 18, 42 and 162 hours after segmental allergen provocation. 2010 Scand. J. Immunol. pmid:20384875
Lieber G et al. Concomitant activity of histamine and cysteinyl leukotrienes on porcine nasal mucosal vessels and nasal inflammation in the rat. 2010 Pharmacology pmid:20453555
Zhou G et al. Atorvastatin reduces plaque vulnerability in an atherosclerotic rabbit model by altering the 5-lipoxygenase pathway. 2010 Cardiology pmid:20234134
Kim MH et al. Effect of leukotriene D4 on mouse embryonic stem cell migration and proliferation: involvement of PI3K/Akt as well as GSK-3β/β-catenin signaling pathways. 2010 J. Cell. Biochem. pmid:20589831
Sakai H et al. Augmented venous responsiveness to leukotriene D(4) in nasal septal mucosae of repeatedly antigen-challenged rats. 2010 Eur. J. Pharmacol. pmid:20638382
Finkensieper A et al. The 5-lipoxygenase pathway regulates vasculogenesis in differentiating mouse embryonic stem cells. 2010 Cardiovasc. Res. pmid:19965960
Mizutani N et al. Effect of TA-270, a novel quinolinone derivative, on antigen-induced nasal blockage in a guinea pig model of allergic rhinitis. 2009 Eur. J. Pharmacol. pmid:19022242
Fang SH et al. Pranlukast attenuates ischemia-like injury in endothelial cells via inhibiting reactive oxygen species production and nuclear factor-kappaB activation. 2009 J. Cardiovasc. Pharmacol. pmid:19129732
Selg E et al. Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites. 2009 Prostaglandins Other Lipid Mediat. pmid:19103301