Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Asbestosis D001195 8 associated lipids
Sneezing D012912 6 associated lipids
Aspergillosis, Allergic Bronchopulmonary D001229 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Authors Title Published Journal PubMed Link
Campos MR et al. Differential kinase requirement for enhancement of Fc gammaR-mediated phagocytosis in alveolar macrophages by leukotriene B4 vs. D4. 2009 Mol. Immunol. pmid:19223078
Lee TH et al. Leukotriene E4: perspective on the forgotten mediator. 2009 J. Allergy Clin. Immunol. pmid:19482346
Austen KF et al. The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications. 2009 J. Allergy Clin. Immunol. pmid:19647860
Muraki M et al. Inhaled montelukast inhibits cysteinyl-leukotriene-induced bronchoconstriction in ovalbumin-sensitized guinea-pigs: the potential as a new asthma medication. 2009 Int. Immunopharmacol. pmid:19706339
Baker N et al. Lipoxin A4: anti-inflammatory and anti-angiogenic impact on endothelial cells. 2009 J. Immunol. pmid:19265161
Boehmler AM et al. The CysLT1 ligand leukotriene D4 supports alpha4beta1- and alpha5beta1-mediated adhesion and proliferation of CD34+ hematopoietic progenitor cells. 2009 J. Immunol. pmid:19454674
Mori M et al. Eosinophil superoxide anion generation induced by adhesion molecules and leukotriene D4. 2009 Int. Arch. Allergy Immunol. pmid:19494502
Yang HS et al. [Effects of leukotriene receptor antagonists on vascular endothelial growth factor and its receptors in a sensitized rat model]. 2009 Zhonghua Jie He He Hu Xi Za Zhi pmid:19575935
Pugliese AM et al. Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells. 2009 Am. J. Physiol., Cell Physiol. pmid:19625605
Hori M et al. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. 2009 Eur. J. Pharmacol. pmid:19616537