|
|
|
|
pmid:
|
Olszewski MA et al. |
Mediators of anaphylaxis but not activated neutrophils augment cholinergic responses of equine small airways. |
1999 |
Am. J. Physiol. |
pmid:10070118
|
White IJ et al. |
A continuous fluorometric assay for leukotriene D4 hydrolase. |
1999 |
Anal. Biochem. |
pmid:10075814
|
Takami M and Tsukada W |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents. |
1999 |
Eur. J. Pharmacol. |
pmid:10082207
|
Pitt CM and Nally JE |
Angiotensin II-mediated potentiation of endothelin-1-evoked bronchial contractions: a role for leukotrienes? |
1999 |
Pulm Pharmacol Ther |
pmid:10208831
|
Mulder A et al. |
Effect of inhaled leukotriene D4 on airway eosinophilia and airway hyperresponsiveness in asthmatic subjects. |
1999 |
Am. J. Respir. Crit. Care Med. |
pmid:10228127
|
Lynch KR et al. |
Characterization of the human cysteinyl leukotriene CysLT1 receptor. |
1999 |
Nature |
pmid:10391245
|
Clish CB et al. |
Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. |
1999 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:10393980
|
Han HJ et al. |
Leukotriene D4 inhibits Na+ uptake through cAMP and PLC pathways in primary cultured renal proximal tubular cells. |
1999 |
Kidney Blood Press. Res. |
pmid:10394108
|
Busse WW et al. |
Leukotriene pathway inhibitors in asthma and chronic obstructive pulmonary disease. |
1999 |
Clin. Exp. Allergy |
pmid:10421833
|
Olszewski MA et al. |
Pre- and postjunctional effects of inflammatory mediators in horse airways. |
1999 |
Am. J. Physiol. |
pmid:10444527
|
Takizawa T et al. |
Effects of a new antiallergic agent, VUF-K-8788, on experimental asthmatic reactions in guinea pigs. |
1999 |
Pharmacology |
pmid:10450067
|
Sarau HM et al. |
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor. |
1999 |
Mol. Pharmacol. |
pmid:10462554
|
Lankisch TO et al. |
High-affinity cholecystokinin type A receptor/cytosolic phospholipase A2 pathways mediate Ca2+ oscillations via a positive feedback regulation by calmodulin kinase in pancreatic acini. |
1999 |
Eur. J. Cell Biol. |
pmid:10535305
|
Yang XX et al. |
The beta(2)-agonist salbutamol inhibits bronchoconstriction and leukotriene D(4) synthesis after dry gas hyperpnea in the guinea-pig. |
1999 |
Pulm Pharmacol Ther |
pmid:10545287
|
Yamashita T and Kokubun S |
Nonselective cationic currents activated by acetylcholine in swine tracheal smooth muscle cells. |
1999 |
Can. J. Physiol. Pharmacol. |
pmid:10588484
|
Mehta KA et al. |
Effect of formulation and process variables on porosity parameters and release rates from a multi unit erosion matrix of a poorly soluble drug. |
2000 |
J Control Release |
pmid:10640593
|
Mayatepek E et al. |
Analysis of leukotrienes in cerebrospinal fluid of a reference population and patients with inborn errors of metabolism: further evidence for a pathognomonic profile in LTC(4)-synthesis deficiency. |
2000 |
Clin. Chim. Acta |
pmid:10686285
|
Laberge S et al. |
Antigen-induced airway inflammation and hyper-responsiveness does not enhance airway responses to a subsequent antigen challenge in rats. |
2000 |
Respir Med |
pmid:10714478
|
Thodeti CK et al. |
Leukotriene D(4) triggers an association between gbetagamma subunits and phospholipase C-gamma1 in intestinal epithelial cells. |
2000 |
J. Biol. Chem. |
pmid:10734140
|
Underwood DC et al. |
SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. |
2000 |
J. Pharmacol. Exp. Ther. |
pmid:10734180
|
Ahmed T et al. |
Inhibition of allergic late airway responses by inhaled heparin-derived oligosaccharides. |
2000 |
J. Appl. Physiol. |
pmid:10797135
|
Macfarlane AJ et al. |
Sputum cysteinyl leukotrienes increase 24 hours after allergen inhalation in atopic asthmatics. |
2000 |
Am. J. Respir. Crit. Care Med. |
pmid:10806153
|
Ravasi S et al. |
A kinetic binding study to evaluate the pharmacological profile of a specific leukotriene C(4) binding site not coupled to contraction in human lung parenchyma. |
2000 |
Mol. Pharmacol. |
pmid:10825389
|
Tran HS et al. |
The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. |
2000 |
Shock |
pmid:10847636
|
Heise CE et al. |
Characterization of the human cysteinyl leukotriene 2 receptor. |
2000 |
J. Biol. Chem. |
pmid:10851239
|
Fukuyama S et al. |
Effect of eotaxin and platelet-activating factor on airway inflammation and hyperresponsiveness in guinea pigs in vivo. |
2000 |
Am. J. Respir. Crit. Care Med. |
pmid:10852755
|
Davis HM et al. |
Human granulocyte CD11b expression as a pharmacodynamic biomarker of inflammation. |
2000 |
J. Immunol. Methods |
pmid:10854607
|
Ballart B et al. |
Synthesis and pharmacological evaluation of new 4-2-(7-heterocyclemethoxynaftalen-2-ylmethoxy)ethylbenzoic acids as LTD(4)-antagonists. |
2000 |
Eur J Med Chem |
pmid:10858604
|
McMahon B et al. |
Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors. |
2000 |
J. Biol. Chem. |
pmid:10869343
|
Arakida Y et al. |
In vivo pharmacologic profile of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors. |
2000 |
Jpn. J. Pharmacol. |
pmid:10887942
|
Lopes LR et al. |
Reduced inflammatory response in rats fed fat-rich diets: role of leukotrienes. |
2000 |
Life Sci. |
pmid:10896024
|
Mayatepek E et al. |
Defects in the synthesis of cysteinyl leukotrienes: a new group of inborn errors of metabolism. |
2000 |
J. Inherit. Metab. Dis. |
pmid:10896305
|
Blain JF and Sirois P |
Involvement of LTD(4)in allergic pulmonary inflammation in mice: modulation by cysLT(1)antagonist MK-571. |
2000 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:10913229
|
Takasaki J et al. |
The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT(2) receptor. |
2000 |
Biochem. Biophys. Res. Commun. |
pmid:10913337
|
Turner DJ et al. |
Bradykinin-induced airway constriction in guinea-pigs: role of leukotriene D(4). |
2000 |
Pulm Pharmacol Ther |
pmid:10930357
|
Bäck M et al. |
Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes. |
2000 |
Eur. J. Pharmacol. |
pmid:10936497
|
Bäck M et al. |
Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes. |
2000 |
Eur. J. Pharmacol. |
pmid:10936498
|
Titos E et al. |
Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis. |
2000 |
Gastroenterology |
pmid:10982774
|
Kodani M et al. |
Intratracheal administration of anaphylatoxin C5a potentiates antigen-induced pulmonary reactions through the prolonged production of cysteinyl-leukotrienes. |
2000 |
Immunopharmacology |
pmid:10996024
|
Ménard G and Bissonnette EY |
Priming of alveolar macrophages by leukotriene D(4): potentiation of inflammation. |
2000 |
Am. J. Respir. Cell Mol. Biol. |
pmid:11017925
|
Ohd JF et al. |
Leukotrienes induce cell-survival signaling in intestinal epithelial cells. |
2000 |
Gastroenterology |
pmid:11040187
|
Thivierge M et al. |
IL-5 up-regulates cysteinyl leukotriene 1 receptor expression in HL-60 cells differentiated into eosinophils. |
2000 |
J. Immunol. |
pmid:11046055
|
Babu KS and Salvi SS |
Aspirin and asthma. |
2000 |
Chest |
pmid:11083703
|
Kalf GF |
Utility of a mouse model for studying the effects of benzene on the myeloid lineage: effects of hydroquinone on a model myeloid system. |
2000 |
J. Toxicol. Environ. Health Part A |
pmid:11086946
|
Nothacker HP et al. |
Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. |
2000 |
Mol. Pharmacol. |
pmid:11093801
|
Hisamatsu K and Nakajima M |
Pranlukast protects leukotriene C4- and D4-induced epithelial cell impairment of the nasal mucosa in vitro. |
2000 |
Life Sci. |
pmid:11105993
|
Robbiani DF et al. |
The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. |
2000 |
Cell |
pmid:11114332
|
Campos MG et al. |
Galphimia glauca organic fraction antagonizes LTD(4)-induced contraction in guinea pig airways. |
2001 |
J Ethnopharmacol |
pmid:11137344
|
Thodeti CK et al. |
The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells. |
2001 |
Exp. Cell Res. |
pmid:11139333
|
Gronert K et al. |
Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. |
2001 |
Am. J. Pathol. |
pmid:11141472
|
Hele DJ et al. |
Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. |
2001 |
Br. J. Pharmacol. |
pmid:11159698
|
Mehta KA et al. |
Release performance of a poorly soluble drug from a novel, Eudragit-based multi-unit erosion matrix. |
2001 |
Int J Pharm |
pmid:11165089
|
Kivity S et al. |
Eosinophil influx into the airways in patients with exercise-induced asthma. |
2000 |
Respir Med |
pmid:11192956
|
Simons FE et al. |
Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast. |
2001 |
Ann. Allergy Asthma Immunol. |
pmid:11206237
|
Accomazzo MR et al. |
Leukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11208655
|
Tohda Y et al. |
Role of chemical mediators in airway hyperresponsiveness in an asthmatic model. |
2001 |
Respiration |
pmid:11223734
|
Maekawa A et al. |
Identification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicing. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11226226
|
Saegusa S et al. |
Leukotriene D(4)-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells. |
2001 |
Eur. J. Pharmacol. |
pmid:11226389
|
Aoki M et al. |
Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs. |
2001 |
J. Pharmacol. Exp. Ther. |
pmid:11259541
|
Massoumi R and Sjölander A |
Leukotriene D(4) affects localisation of vinculin in intestinal epithelial cells via distinct tyrosine kinase and protein kinase C controlled events. |
2001 |
J. Cell. Sci. |
pmid:11329379
|
Bouchelouche K et al. |
The action of cysteinyl-leukotrienes on intracellular calcium mobilization in human detrusor myocytes. |
2001 |
BJU Int. |
pmid:11350414
|
Oliveira SH et al. |
SCF-induced airway hyperreactivity is dependent on leukotriene production. |
2001 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:11350804
|
Snetkov VA et al. |
Mechanisms of leukotriene D4-induced constriction in human small bronchioles. |
2001 |
Br. J. Pharmacol. |
pmid:11350860
|
Bautz F et al. |
Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1. |
2001 |
Blood |
pmid:11369634
|
Bouchelouche K et al. |
Calcium signaling in cultured human detrusor smooth muscle cells from patients with interstitial cystitis. |
2001 |
Urology |
pmid:11378073
|
Bouchelouche K et al. |
Cysteinyl-leukotriene D(4) receptors in smooth muscle cells. |
2001 |
Urology |
pmid:11378074
|
Nabe T et al. |
Comparison of cedar pollen-induced allergic rhinitis in passively and actively sensitized guinea pigs. |
2001 |
Jpn. J. Pharmacol. |
pmid:11388645
|
Karaman O et al. |
The comparison of the efficacy of fluticasone propionate with cetirizine in perennial allergic rhinitis. |
2001 Mar-Apr |
Allergol Immunopathol (Madr) |
pmid:11420028
|
Ruck LM et al. |
Synergistic antiallergic activity of combined histamine H1- and cysteinyl leukotriene1-receptor blockade in human bronchus. |
2001 |
Life Sci. |
pmid:11432448
|
Möhle R et al. |
Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. |
2001 |
Ann. N. Y. Acad. Sci. |
pmid:11458515
|
Mizutani N et al. |
Markedly increased nasal blockage by intranasal leukotriene D4 in an experimental allergic rhinitis model: contribution of dilated mucosal blood vessels. |
2001 |
Jpn. J. Pharmacol. |
pmid:11459119
|
Echazarreta AL et al. |
Pulmonary gas exchange and sputum cellular responses to inhaled leukotriene D(4) in asthma. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11463588
|
Shi ZZ et al. |
Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response. |
2001 |
Mol. Cell. Biol. |
pmid:11463821
|
Bäck M et al. |
An alternative pathway for metabolism of leukotriene D(4): effects on contractions to cysteinyl-leukotrienes in the guinea-pig trachea. |
2001 |
Br. J. Pharmacol. |
pmid:11487525
|
Aoki M et al. |
Studies on mechanisms of low emetogenicity of YM976, a novel phosphodiesterase type 4 inhibitor. |
2001 |
J. Pharmacol. Exp. Ther. |
pmid:11504812
|
Thivierge M et al. |
IL-13 and IL-4 up-regulate cysteinyl leukotriene 1 receptor expression in human monocytes and macrophages. |
2001 |
J. Immunol. |
pmid:11509632
|
Nishimura H et al. |
Acute effects of prostaglandin D2 to induce airflow obstruction and airway microvascular leakage in guinea pigs: role of thromboxane A2 receptors. |
2001 |
Prostaglandins Other Lipid Mediat. |
pmid:11519790
|
Hui Y et al. |
The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization. |
2001 |
J. Biol. Chem. |
pmid:11591709
|
Ro JY et al. |
The inhibitory mechanism of rebamipide on the mediator release in the guinea pig lung mast cells activated with specific antigen-antibody reactions. |
2001 |
Pharmacology |
pmid:11598424
|
Gauvreau GM et al. |
Inhaled leukotriene E(4), but not leukotriene D(4), increased airway inflammatory cells in subjects with atopic asthma. |
2001 |
Am. J. Respir. Crit. Care Med. |
pmid:11704602
|
Young RN |
Discovery of montelukast: a once-a-day oral antagonist of leukotriene D4 for the treatment of chronic asthma. |
2001 |
Prog Med Chem |
pmid:11774796
|
Suzuki R and Freed AN |
Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11779726
|
Obase Y et al. |
Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. |
2002 |
Chest |
pmid:11796443
|
Kawada N et al. |
The effect of leukotriene D(4) inhalation on the antigen-induced airway hyperresponsiveness and inflammation in 5-lipoxygenase gene-deficient mice. |
2001 |
Int. Arch. Allergy Immunol. |
pmid:11815738
|
Fukuishi N et al. |
Antiallergic effect of ardisiaquinone A, a potent 5-lipoxygenase inhibitor. |
2001 |
Phytomedicine |
pmid:11824521
|
Sakata K and Bäck M |
Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma. |
2002 |
Eur. J. Pharmacol. |
pmid:11834255
|
Tada N et al. |
Experimental otitis media with effusion induced by leukotriene D4. |
2002 |
Auris Nasus Larynx |
pmid:11893446
|
Tokuyama K et al. |
Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo. |
2002 |
Pharmacology |
pmid:11893899
|
Neu IS et al. |
Leukotrienes in patients with clinically active multiple sclerosis. |
2002 |
Acta Neurol. Scand. |
pmid:11903112
|
Lee KH et al. |
Increased expression of endothelial cell adhesion molecules due to mediator release from human foreskin mast cells stimulated by autoantibodies in chronic urticaria sera. |
2002 |
J. Invest. Dermatol. |
pmid:11918713
|
Allakhverdi Z et al. |
Inhibition of antigen-induced eosinophilia and airway hyperresponsiveness by antisense oligonucleotides directed against the common beta chain of IL-3, IL-5, GM-CSF receptors in a rat model of allergic asthma. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11934731
|
Nagata M et al. |
Leukotriene D4 upregulates eosinophil adhesion via the cysteinyl leukotriene 1 receptor. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11941318
|
Paruchuri S et al. |
Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells. |
2002 |
J. Cell. Sci. |
pmid:11956320
|
Ravasi S et al. |
Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. |
2002 |
Biochem. Pharmacol. |
pmid:11996896
|
Nag S et al. |
Interleukin-2-induced increased airway responsiveness and lung Th2 cytokine expression occur after antigen challenge through the leukotriene pathway. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:12045130
|
Bandeira-Melo C et al. |
Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils. |
2002 |
J. Allergy Clin. Immunol. |
pmid:12063527
|
Thodeti CK et al. |
Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells. |
2002 |
Biochem. J. |
pmid:12071848
|
Bäck M |
Functional characteristics of cysteinyl-leukotriene receptor subtypes. |
2002 |
Life Sci. |
pmid:12072150
|
Li X and Weinman SA |
Mrp2 modulates the activity of chloride channels in isolated hepatocytes. |
2002 |
Hepatology |
pmid:12085350
|