Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Sneezing D012912 6 associated lipids
Asbestosis D001195 8 associated lipids
Aspergillosis, Allergic Bronchopulmonary D001229 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Authors Title Published Journal PubMed Link
Salim T et al. The inflammatory mediator leukotriene D₄ induces subcellular β-catenin translocation and migration of colon cancer cells. 2014 Exp. Cell Res. pmid:24211746
Kawakami Y et al. Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies. 2014 Biochim. Biophys. Acta pmid:24361619
Bäck M et al. Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. 2014 Br. J. Pharmacol. pmid:24588652
Syslová K et al. Immunomagnetic molecular probe with UHPLC-MS/MS: a promising way for reliable bronchial asthma diagnostics based on quantification of cysteinyl leukotrienes. 2013 Jul-Aug J Pharm Biomed Anal pmid:23644905
Jørgensen ST et al. Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization. 2013 Cell. Physiol. Biochem. pmid:23485744
Matsuse H et al. Differential airway inflammatory responses in asthma exacerbations induced by respiratory syncytial virus and influenza virus a. 2013 Int. Arch. Allergy Immunol. pmid:23689185
Rodríguez-Lagunas MJ et al. 5-Hydroxyeicosatetraenoic acid and leukotriene D4 increase intestinal epithelial paracellular permeability. 2013 Int. J. Biochem. Cell Biol. pmid:23583294
Kouyama S et al. A contraction assay system using primary cultured mouse bronchial smooth muscle cells. 2013 Int. Arch. Allergy Immunol. pmid:23711859
Kanaoka Y et al. Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand. 2013 J. Biol. Chem. pmid:23504326
Kang KH et al. Protection of dopaminergic neurons by 5-lipoxygenase inhibitor. 2013 Neuropharmacology pmid:23800665