Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Airway Obstruction D000402 13 associated lipids
Asbestosis D001195 8 associated lipids
Aspergillosis, Allergic Bronchopulmonary D001229 2 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Edema D004487 152 associated lipids
Glomerulonephritis D005921 35 associated lipids
Leukemia D007938 74 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Per page 10 20 50 100 | Total 562
Authors Title Published Journal PubMed Link
Patel JP et al. Beneficial effects of combined thromboxane and leukotriene receptor antagonism in hemorrhagic shock. 1995 Crit. Care Med. pmid:7867347
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Tanaka T et al. Protective effect of peptide leukotriene antagonist on renal failure induced by a tourniquet in rabbits. 1995 Forensic Sci. Int. pmid:7875619
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Hoheisel U and Mense S Leukotriene D4 depresses the mechanosensitivity of group III and IV muscle receptors in the rat. 1994 Neuroreport pmid:8025261
Herd CM et al. Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits. 1994 Br. J. Pharmacol. pmid:8032653
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Han H et al. Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. 1994 Am. J. Physiol. pmid:8203604
Hyun CS and Binder HJ Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. 1993 Am. J. Physiol. pmid:8214069
Pawloski JR and Chapnick BM Antagonism of LTD4-evoked relaxation in canine renal artery and vein. 1993 Am. J. Physiol. pmid:8214135
Manning PJ et al. Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms. 1993 Am. Rev. Respir. Dis. pmid:8214949
Arakawa H et al. Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor. 1993 Br. J. Pharmacol. pmid:8220872
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Yoshikawa S et al. Modulation of acetylcholine release from the myenteric plexus of guinea-pig ileum by 5-lipoxygenase metabolites of arachidonic acid. 1993 Eur. J. Pharmacol. pmid:8223906
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Krauss AH et al. Determination of leukotriene effects on human neutrophil chemotaxis in vitro by differential assessment of cell motility and polarity. 1994 J. Leukoc. Biol. pmid:8301217
Oliva D et al. Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. 1994 J. Pharmacol. Exp. Ther. pmid:8301553
Howell RE et al. Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs. 1994 J. Pharmacol. Exp. Ther. pmid:8301576
Lee TH and Christie PE Leukotrienes and aspirin induced asthma. 1993 Thorax pmid:8303620
Nathan RA et al. Inhaled ICI 204,219 blocks antigen-induced bronchoconstriction in subjects with bronchial asthma. 1994 Chest pmid:8306751
Metters KM and Zamboni RJ Photoaffinity labeling of the leukotriene D4 receptor in guinea pig lung. 1993 J. Biol. Chem. pmid:8384212
Shikada K and Tanaka S Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121. 1993 Br. J. Pharmacol. pmid:8401920
Diener M and Scharrer E The leukotriene D4 receptor blocker, SK&F 104353, inhibits volume regulation in isolated crypts from the rat distal colon. 1993 Eur. J. Pharmacol. pmid:8405093
Chen C et al. Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. 1995 Cell pmid:8548809
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Bonnefoi MS et al. Subchronic toxicity studies with the leukotriene D4 antagonist RG 12525. 1995 Fundam Appl Toxicol pmid:8566477