Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Endotoxemia D019446 27 associated lipids
Carotid Stenosis D016893 15 associated lipids
Sneezing D012912 6 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Leukemia D007938 74 associated lipids
Glomerulonephritis D005921 35 associated lipids
Edema D004487 152 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

Download all related citations
Per page 10 20 50 100 | Total 562
Authors Title Published Journal PubMed Link
Yoshikawa S et al. Modulation of acetylcholine release from the myenteric plexus of guinea-pig ileum by 5-lipoxygenase metabolites of arachidonic acid. 1993 Eur. J. Pharmacol. pmid:8223906
Krauss AH and Woodward DF Polymorphonuclear leukocyte infiltration into the subretinal choroid and optic nerve in response to leukotrienes. 1993 Invest. Ophthalmol. Vis. Sci. pmid:8258528
Weide I et al. Intravascular cysteinyl-leukotriene formation by clotting whole human blood. Evidence from clamped umbilical vein segments and thrombus specimens. 1993 Thromb. Res. pmid:8122190
Hyun CS and Binder HJ Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. 1993 Am. J. Physiol. pmid:8214069
Pawloski JR and Chapnick BM Antagonism of LTD4-evoked relaxation in canine renal artery and vein. 1993 Am. J. Physiol. pmid:8214135
Manning PJ et al. Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms. 1993 Am. Rev. Respir. Dis. pmid:8214949
Smith LJ et al. Inhibition of leukotriene D4-induced bronchoconstriction in subjects with asthma: a concentration-effect study of ICI 204,219. 1993 Clin. Pharmacol. Ther. pmid:8222486
Metters KM and Zamboni RJ Photoaffinity labeling of the leukotriene D4 receptor in guinea pig lung. 1993 J. Biol. Chem. pmid:8384212
Diener M and Scharrer E The leukotriene D4 receptor blocker, SK&F 104353, inhibits volume regulation in isolated crypts from the rat distal colon. 1993 Eur. J. Pharmacol. pmid:8405093
Ramis I et al. Application of totally automated on-line sample clean up system for extraction and high-performance liquid chromatography separation of peptide leukotrienes. 1993 Nov-Dec J Pharm Biomed Anal pmid:8123725
Hoheisel U and Mense S Leukotriene D4 depresses the mechanosensitivity of group III and IV muscle receptors in the rat. 1994 Neuroreport pmid:8025261
Undem BJ et al. Recombinant stem cell factor-induced mast cell activation and smooth muscle contraction in human bronchi. 1994 Am. J. Respir. Cell Mol. Biol. pmid:7524570
Ibe BO et al. Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. 1994 Eur. J. Clin. Invest. pmid:8187808
Fauler J et al. Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. 1994 Arthritis Rheum. pmid:8129769
Krell RD et al. Preclinical exploration of the potential antiinflammatory properties of the peptide leukotriene antagonist ICI 204,219 (Accolate). 1994 Ann. N. Y. Acad. Sci. pmid:7825851
Ellis JL and Undem BJ Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. 1994 Am. J. Respir. Crit. Care Med. pmid:8111568
Tudorić N et al. Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. 1994 Int. Arch. Allergy Immunol. pmid:8111247
Oliva D et al. Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. 1994 J. Pharmacol. Exp. Ther. pmid:8301553
Howell RE et al. Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs. 1994 J. Pharmacol. Exp. Ther. pmid:8301576
Kano M Calcium-induced long-lasting potentiation of GABAergic currents in cerebellar Purkinje cells. 1994 Jpn. J. Physiol. pmid:7752516