Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Airway Obstruction D000402 13 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Leukemia D007938 74 associated lipids
Glomerulonephritis D005921 35 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Carotid Stenosis D016893 15 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Endotoxemia D019446 27 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

Download all related citations
Per page 10 20 50 100 | Total 562
Authors Title Published Journal PubMed Link
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Callaghan DH et al. Respiratory tract eicosanoid measurement using microdialysis sampling and GC/MS detection. 1994 Pulm Pharmacol pmid:8003850
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Chan CC et al. Leukotriene D4-induced increases in cytosolic calcium in THP-1 cells: dependence on extracellular calcium and inhibition with selective leukotriene D4 receptor antagonists. 1994 J. Pharmacol. Exp. Ther. pmid:8014876
Arakawa H et al. Effect of maturation on airway plasma exudation induced by eicosanoids in guinea pig. 1994 Eur. J. Pharmacol. pmid:7982451
Kelley M et al. Induction of peroxisomal enzymes by a tetrazole-substituted 2-quinolinylmethoxy leukotriene D4 antagonist. 1994 Fundam Appl Toxicol pmid:7982537
Ellis JL and Undem BJ Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. 1994 Am. J. Respir. Crit. Care Med. pmid:8111568
Dahlén B et al. The leukotriene-antagonist ICI-204,219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. 1994 Eur. Respir. J. pmid:8162986
Fiore S et al. Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor. 1994 J. Exp. Med. pmid:8006586
Han H et al. Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. 1994 Am. J. Physiol. pmid:8203604
Tudorić N et al. Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. 1994 Int. Arch. Allergy Immunol. pmid:8111247
Abela A and Daniel EE Neural and myogenic effects of leukotrienes C4, D4, and E4 on canine bronchial smooth muscle. 1994 Am. J. Physiol. pmid:8179018
Kurosawa M et al. Inhibition by a novel peptide leukotriene receptor antagonist ONO-1078 of airway wall thickening and airway hyperresponsiveness to histamine induced by leukotriene C4 or leukotriene D4 in guinea-pigs. 1994 Clin. Exp. Allergy pmid:7842366
Oliva D et al. Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle. 1994 J. Pharmacol. Exp. Ther. pmid:8301553
Howell RE et al. Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs. 1994 J. Pharmacol. Exp. Ther. pmid:8301576
Herd CM et al. Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on antigen-induced airway responses in neonatally immunized rabbits. 1994 Br. J. Pharmacol. pmid:8032653
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Thioudellet C et al. Molecular and functional characterization of recombinant human gamma-glutamyltransferase. Coupling of its activity to glutathione levels in V79 cells. 1994 Eur. J. Biochem. pmid:7913033
Mion F et al. Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor. 1994 Gut pmid:8174986
Salari H et al. Involvement of immunologic mechanisms in a guinea pig model of western red cedar asthma. 1994 J. Allergy Clin. Immunol. pmid:8182231
Kano M Calcium-induced long-lasting potentiation of GABAergic currents in cerebellar Purkinje cells. 1994 Jpn. J. Physiol. pmid:7752516
Szarek JL and Valentovic MA Release of prostaglandin E2 and leukotriene C4/D4 from airway segments isolated from rats after exposure to ozone for 20 months. 1995 Toxicology pmid:7624868
Chen C et al. Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. 1995 Cell pmid:8548809
Goldhill JM et al. Neural control of mouse small intestinal longitudinal muscle: interactions with inflammatory mediators. 1995 J. Pharmacol. Exp. Ther. pmid:7616450
Grönroos E et al. The regulation of leukotriene D4-induced calcium influx in human epithelial cells involves protein tyrosine phosphorylation. 1995 Cell Calcium pmid:7621531
Wettstein M et al. Metabolism of cysteinyl leukotrienes in the perfused rat liver: the influence of endotoxin pretreatment and the cellular hydration state. 1995 Hepatology pmid:7601416
Nagase T et al. In vitro airway and tissue response to antigen in sensitized rats. Role of serotonin and leukotriene D4. 1995 Am. J. Respir. Crit. Care Med. pmid:7599867
Porreca E et al. Modulation of rat vascular smooth muscle cell (VSMC) proliferation by cysteinyl leukotriene D4: a role for mediation of interleukin 1. 1995 Atherosclerosis pmid:7755646
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Cohen P et al. Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis. 1995 Am. J. Physiol. pmid:7544535
Iwamoto I et al. Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs. 1995 Int. Arch. Allergy Immunol. pmid:7647588
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Kelefiotis D et al. Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. 1995 Prostaglandins pmid:7659782
Donnelly AL et al. The leukotriene D4-receptor antagonist, ICI 204,219, relieves symptoms of acute seasonal allergic rhinitis. 1995 Am. J. Respir. Crit. Care Med. pmid:7767514
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Tanaka T et al. Protective effect of peptide leukotriene antagonist on renal failure induced by a tourniquet in rabbits. 1995 Forensic Sci. Int. pmid:7875619
Kanwar S et al. Leukotriene C4/D4 induces P-selectin and sialyl Lewis(x)-dependent alterations in leukocyte kinetics in vivo. 1995 Circ. Res. pmid:7554141
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Datta YH et al. Peptido-leukotrienes are potent agonists of von Willebrand factor secretion and P-selectin surface expression in human umbilical vein endothelial cells. 1995 Circulation pmid:7586318
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Herron DK et al. Visualization and comparison of molecular dynamics simulations of leukotriene C4, leukotriene D4, and leukotriene E4. 1995 J Mol Graph pmid:8820302
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Porreca E et al. Cysteinyl-leukotriene D4 induced IL-1 beta expression and release in rat vascular smooth muscle cells. 1995 Atherosclerosis pmid:7661877
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Ganbo T et al. The effects of leukotrienes C4 and D4 on ciliary activity of human paranasal sinus mucosa in vitro. 1995 Rhinology pmid:8919211
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