| MeSH term | MeSH ID | Detail |
|---|---|---|
| Airway Obstruction | D000402 | 13 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Glomerulonephritis | D005921 | 35 associated lipids |
| Respiratory Hypersensitivity | D012130 | 18 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Carotid Stenosis | D016893 | 15 associated lipids |
| Asthma, Exercise-Induced | D001250 | 10 associated lipids |
| Endotoxemia | D019446 | 27 associated lipids |
Ltd4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.
Cross Reference
Introduction
To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ltd4?
Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ltd4
PubChem Associated disorders and diseases
What pathways are associated with Ltd4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ltd4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ltd4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ltd4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Ltd4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ltd4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Ltd4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ménard G and Bissonnette EY | Priming of alveolar macrophages by leukotriene D(4): potentiation of inflammation. | 2000 | Am. J. Respir. Cell Mol. Biol. | pmid:11017925 |
| Ohd JF et al. | Leukotrienes induce cell-survival signaling in intestinal epithelial cells. | 2000 | Gastroenterology | pmid:11040187 |
| Thivierge M et al. | IL-5 up-regulates cysteinyl leukotriene 1 receptor expression in HL-60 cells differentiated into eosinophils. | 2000 | J. Immunol. | pmid:11046055 |
| Babu KS and Salvi SS | Aspirin and asthma. | 2000 | Chest | pmid:11083703 |
| Kalf GF | Utility of a mouse model for studying the effects of benzene on the myeloid lineage: effects of hydroquinone on a model myeloid system. | 2000 | J. Toxicol. Environ. Health Part A | pmid:11086946 |
| Nothacker HP et al. | Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. | 2000 | Mol. Pharmacol. | pmid:11093801 |
| Hisamatsu K and Nakajima M | Pranlukast protects leukotriene C4- and D4-induced epithelial cell impairment of the nasal mucosa in vitro. | 2000 | Life Sci. | pmid:11105993 |
| Robbiani DF et al. | The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes. | 2000 | Cell | pmid:11114332 |
| Campos MG et al. | Galphimia glauca organic fraction antagonizes LTD(4)-induced contraction in guinea pig airways. | 2001 | J Ethnopharmacol | pmid:11137344 |
| Thodeti CK et al. | The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells. | 2001 | Exp. Cell Res. | pmid:11139333 |
| Gronert K et al. | Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses. | 2001 | Am. J. Pathol. | pmid:11141472 |
| Hele DJ et al. | Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. | 2001 | Br. J. Pharmacol. | pmid:11159698 |
| Mehta KA et al. | Release performance of a poorly soluble drug from a novel, Eudragit-based multi-unit erosion matrix. | 2001 | Int J Pharm | pmid:11165089 |
| Kivity S et al. | Eosinophil influx into the airways in patients with exercise-induced asthma. | 2000 | Respir Med | pmid:11192956 |
| Simons FE et al. | Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast. | 2001 | Ann. Allergy Asthma Immunol. | pmid:11206237 |
| Accomazzo MR et al. | Leukotriene D4-induced activation of smooth-muscle cells from human bronchi is partly Ca2+-independent. | 2001 | Am. J. Respir. Crit. Care Med. | pmid:11208655 |
| Tohda Y et al. | Role of chemical mediators in airway hyperresponsiveness in an asthmatic model. | 2001 | Respiration | pmid:11223734 |
| Maekawa A et al. | Identification in mice of two isoforms of the cysteinyl leukotriene 1 receptor that result from alternative splicing. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11226226 |
| Saegusa S et al. | Leukotriene D(4)-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells. | 2001 | Eur. J. Pharmacol. | pmid:11226389 |
| Aoki M et al. | Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs. | 2001 | J. Pharmacol. Exp. Ther. | pmid:11259541 |