Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Airway Obstruction D000402 13 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Leukemia D007938 74 associated lipids
Glomerulonephritis D005921 35 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Carotid Stenosis D016893 15 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Endotoxemia D019446 27 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

Download all related citations
Per page 10 20 50 100 | Total 562
Authors Title Published Journal PubMed Link
Cohen P et al. Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis. 1995 Am. J. Physiol. pmid:7544535
Goldhill J et al. Interleukin-4 modulates cholinergic neural control of mouse small intestinal longitudinal muscle. 1997 Am. J. Physiol. pmid:9176223
Rajah R et al. Leukotriene D4 induces MMP-1, which functions as an IGFBP protease in human airway smooth muscle cells. 1996 Am. J. Physiol. pmid:8997273
Olszewski MA et al. Mediators of anaphylaxis but not activated neutrophils augment cholinergic responses of equine small airways. 1999 Am. J. Physiol. pmid:10070118
Olszewski MA et al. Pre- and postjunctional effects of inflammatory mediators in horse airways. 1999 Am. J. Physiol. pmid:10444527
Hyun CS and Binder HJ Mechanism of leukotriene D4 stimulation of Cl- secretion in rat distal colon in vitro. 1993 Am. J. Physiol. pmid:8214069
Pawloski JR and Chapnick BM Antagonism of LTD4-evoked relaxation in canine renal artery and vein. 1993 Am. J. Physiol. pmid:8214135
Sato E et al. Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. 1998 Am. J. Physiol. pmid:9609736
Han H et al. Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction. 1994 Am. J. Physiol. pmid:8203604
Ganbo T et al. Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. 1996 Am. J. Physiol. pmid:8770059