Ltd4

Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Asthma and Virus Diseases. The involved functions are known as uptake, Phosphorylation, Signal Transduction, symporter activity and Regulation. Ltd4 often locates in Protoplasm, Mucous Membrane, Membrane, Extracellular and Epithelium. The associated genes with Ltd4 are TYRO3 gene, RAF1 gene, serine-borate complex, ITGAM gene and ITGB2 gene. The related lipids are Lipopolysaccharides.

Cross Reference

Introduction

To understand associated biological information of Ltd4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ltd4?

Ltd4 is suspected in Asthma, Inflammatory Bowel Diseases, Inflammatory disorder, Pneumonia, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ltd4

MeSH term MeSH ID Detail
Airway Obstruction D000402 13 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Leukemia D007938 74 associated lipids
Glomerulonephritis D005921 35 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Carotid Stenosis D016893 15 associated lipids
Asthma, Exercise-Induced D001250 10 associated lipids
Endotoxemia D019446 27 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Ltd4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ltd4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ltd4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ltd4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ltd4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ltd4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Ltd4

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Per page 10 20 50 100 | Total 562
Authors Title Published Journal PubMed Link
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Manning PJ et al. Exercise-induced refractoriness in asthmatic subjects involves leukotriene and prostaglandin interdependent mechanisms. 1993 Am. Rev. Respir. Dis. pmid:8214949
Arakawa H et al. Leukotriene D4- and prostaglandin F2 alpha-induced airflow obstruction and airway plasma exudation in guinea-pig: role of thromboxane and its receptor. 1993 Br. J. Pharmacol. pmid:8220872
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Nathan RA et al. Inhaled ICI 204,219 blocks antigen-induced bronchoconstriction in subjects with bronchial asthma. 1994 Chest pmid:8306751
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Shikada K and Tanaka S Influence of epithelium on the inhibition of melittin-induced contraction of guinea-pig isolated trachea by the potassium channel opener NIP-121. 1993 Br. J. Pharmacol. pmid:8401920
Diener M and Scharrer E The leukotriene D4 receptor blocker, SK&F 104353, inhibits volume regulation in isolated crypts from the rat distal colon. 1993 Eur. J. Pharmacol. pmid:8405093
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Dudek SM and Friedlander MJ Developmental down-regulation of LTD in cortical layer IV and its independence of modulation by inhibition. 1996 Neuron pmid:8663986
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Konno A et al. Role of substance P in the vascular response of nasal mucosa in nasal allergy. 1996 Ann. Otol. Rhinol. Laryngol. pmid:8712637
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Ganbo T et al. Leukotriene C4 inhibits ciliary activity in the presence of gamma-glutamyl transpeptidase. 1996 Am. J. Physiol. pmid:8770059
Shikada K and Tanaka S Effect of the K+ channel openers NIP-121 and cromakalim on melittin-induced relaxation of guinea-pig isolated trachea. 1996 Prostaglandins pmid:8792445
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Tominaga M et al. ONO-1078 antagonizes diarrhea-causing changes in ion transport and smooth muscle contraction induced by peptidoleukotrienes in rat and human colon in vitro. 1996 J. Pharmacol. Exp. Ther. pmid:8819486
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Diamant Z et al. The effect of inhaled leukotriene D4 and methacholine on sputum cell differentials in asthma. 1997 Am. J. Respir. Crit. Care Med. pmid:9105062
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Maehr H and Yang R Structure optimization of a leukotriene D4 antagonist by combinatorial chemistry in solution. 1997 Bioorg. Med. Chem. pmid:9113326